Hey Oa

Dr. Jackie Whittaker, an assistant professor of physical therapy at the University of Alberta, compares primary, secondary, and tertiary OA prevention, discusses the challenges and opportunities for research with youth populations, and chats about using Twitter for research. You can find her at https://www.ualberta.ca/rehabilitation/about-us/contact-us/faculty-directory/jackie-whittaker or on twitter @jwhittak_physio

Dr. Jamie MacKay, a musculoskeletal radiologist and clinical research fellow (and 3rd year PhD student!) in the Department of Radiology at the University of Cambridge, discusses career decisions, musculoskeletal imaging, and preparing for his upcoming OARSI collaborative scholarship at Stanford University. You can find out more about Dr. MacKay and his research on twitter (@dr_jamie_mackay) or at http://radiology.medschl.cam.ac.uk/about-us/departmental-staff/phd-students/jamie-mackay. The systematic review and meta-analysis paper that was mentioned can be found at: https://www.oarsijournal.com/article/S1063-4584(18)31069-0/abstract

Dr. Timothy Griffin, an associate member of the Oklahoma Medical Research Foundation and Adjunct Associate Professor at the University of Oklahoma, discusses metabolism and inflammation in osteoarthritis, animal models of obesity, and what it’s like to work at a private, non-profit research foundation. More information about Dr. Griffin's research can be found at: https://griffint.omrf.org/

Dr. Gillian Hawker, a clinician scientist, professor, and chair of medicine at the University of Toronto, discusses why we need to classify OA as a serious disease, the need for consistent definitions of OA, and remaining sources of bias in the treatment of women with OA. Find more about the OARSI white paper at: https://www.oarsi.org/research/oa-serious-disease This podcast is made possible with funding from Flexion. 

Dr. Tuhina Neogi, professor of medicine at Boston University’s School of Medicine and professor of epidemiology at Boston University’s School of Public Health, shares her knowledge about imaging, pain, and mentoring. Find out more at: https://profiles.bu.edu/Tuhina.Neogi http://blog.arthritis.org/news/arthritis-research-tuhina-neogi/

Dr. Carla Scanzello, Section Chief of Rheumatology at the Corporal Michael J. Cresenz (Philadelphia) VA Medical Center, assistant professor at the University of Pennsylvania Perelman School of Medicine, and current program chair for the 2018 OARSI World Congress on Osteoarthritis discusses what’s in store at the upcoming conference and what not to miss! The congress runs from April 26th to Sunday April 29th, 2018 in Liverpool, UK. More information can be found at: https://2018.oarsi.org/

Professor Peter Choong, MD, lead chief investigator for OPUS, the Centre of Research Excellence in Total Joint Replacement, discusses how research can help optimize outcomes, equity, cost-effectiveness, and patient selection for joint replacement. More information about Professor Choong’s research and OPUS can be found at medicine.unimelb.edu.au/surgery/opus or on twitter @OPUSunimelb

Three young investigators (early career researchers) share their experiences of working with the Osteoarthritis Initiative Data. (00:17) Michelle Yau, PhD, is a post-doctoral research fellow in the Musculoskeletal Research Group at Hebrew Senior Life, an affiliate hospital of Harvard Medical School in Boston, MA, USA and is a member of the OARSI Young Investigator Committee. Her research focuses on identifying genetic contributions to OA and the role of bone metabolism in OA pathogenesis. (18:42) Jeffrey Driban, PhD, ATC, CSCS, is an Assistant Professor in the Division of Rheumatology at Tufts University School of Medicine and a member of the Special and Scientific Staff at Tufts Medical Center in Boston, MA, USA. The goal of his research is to explore novel biochemical and imaging markers to gain a better understanding of osteoarthritis and potential disease subsets. Find out more on twitter at @jbdriban or at sportsmedres.org where you can find a link to his sports medicine podcast! (35:43) Chuck Ratzlaff,

Dr. Gayle Lester of the National Institutes for Health/National Institute of Arthritis and Musculoskeletal and Skin Disease and Dr. Michael Nevitt of the University of California, San Francisco, discuss the Osteoarthritis Initiative (OAI), a large, publicly available dataset of OA risk factors and outcomes. My-Linh Luong of the University of Melbourne joins Kerry Costello to host this special episode. More information on the recent NIH funding opportunity announcement for research utilizing the OAI dataset can be found at https://grants.nih.gov/grants/guide/pa-files/PA-18-409.html (R01) and https://grants.nih.gov/grants/guide/pa-files/PA-18-408.html (R21). Join the conversation about the OAI on twitter using the hashtag #OAInitiative.

This episode highlights the recent GaitNET OA meeting. Researchers, clinicians, industry members, patient representatives, and advocacy groups from across Canada met to discuss how they could work together to make a greater impact on osteoarthritis-related healthcare.

Jim Schrijvers, a Ph.D. student at the VU University Medical Center in Amsterdam, the Netherlands, and OARSI collaborative scholarship holder at Dalhousie University in Halifax, Nova Scotia, Canada, discusses international research collaboration with his two supervisors: Jaap Harlaar (VUmc) and Derek Rutherford (Dalhousie). More information on the OARSI collaborative scholarship can be found at https://www.oarsi.org/young-investigators/scholarship-awards. You can find contact information for Jim Schrijvers, Jaap Harlaar, and Derek Rutherford through the OARSI member directory and can find more information about their research by looking up Amsterdam Movement Sciences and following the Joint Action Research laboratory on twitter (@daljarlab).

Dr. Krysia Dziedzic, a qualified physiotherapist and professor at Keele University in Staffordshire, UK talks about patient engagement in research and facilitating knowledge mobilization to share research knowledge with a wide range of stakeholders. More information about Dr. Dziedzic’s research can be found at: https://www.keele.ac.uk/pchs/ Dr. Dziedzic mentioned the following resources: Lau et al. Achieving change in primary care--causes of the evidence to practice gap: systematic reviews of reviews. Implement Sci. 2016 Mar 22;11:40. doi: 10.1186/s13012-016-0396-4. Lau et al. Achieving change in primary care--effectiveness of strategies for improving implementation of complex interventions: systematic review of reviews. BMJ Open. 2015 Dec 23;5(12):e009993. doi: 10.1136/bmjopen-2015-009993. Nilsen P. Making sense of implementation theories, models and frameworks. Implement Sci. 2015;10:53.

Dr. Amanda Nelson, an assistant professor of medicine at the University of North Carolina at Chapel Hill in the United States, discusses imaging, the Walk with a Doc program, developing OARSI guidelines, and barriers preventing clinician scientists from staying in research. More information can be found at: Faculty website: https://www.med.unc.edu/tarc/people/amanda-e-nelson-md-mscr Walk With a Doc: http://walkwithadoc.org/ OA Action Alliance: http://oaaction.unc.edu/

Dr. Tom Appleton, a clinician-scientist and assistant professor of rheumatology and medicine at Western University in London, Ontario, Canada talks about having both a clinical career and a research career, OA phenotypes and the potential for patient-specific treatments, and his experience being part of the OARSI year in review for 2017. More information about Dr. Appleton’s research can be found at his website (coming soon): www.appletonlab.com or on twitter: @ctgappleton. The paper mentioned by Dr. Appleton on cell senescence and post-traumatic OA can be found at https://www.nature.com/nm/journal/v23/n6/full/nm.4324.html Remember to check out the new OARSI video at the bottom of the OARSI.org home page! You can also find OARSI on Facebook and Twitter: @OARSInews @OARSI_YI

Dr. Astephen Wilson, a professor of biomedical engineering at Dalhousie University in Halifax, Nova Scotia, Canada and co-director of the Dynamics of Human Motion Laboratory tells us about how she got started in her career in osteoarthritis research, gives some tips on productive collaboration and developing meaningful mentor-mentee relationships, and explains how principal component analysis can be used to interrogate both magnitude and temporal characteristics of gait waveform data.  More information about Dr. Astephen Wilson’s research can be found at: http://www.dal.ca/dohmlab @DOHMlab https://csb2018.ca/ @CSB2018    

Dr. Katz tells us about OARSI’s roles in promoting and facilitating OA research, his vision for the future of OARSI, and how his own research on treatment of meniscal tears fits into the broader goals of the organization. This episode was recorded at the 2017 OARSI World Congress on Osteoarthritis in Las Vegas! The OARSI guidelines mentioned by Dr. Katz can be found here https://www.oarsi.org/education/oarsi-guidelines The patient section of the OARSI website mentioned by Kerry can be found here https://www.oarsi.org/patients You can find out more about Dr. Katz’s research at http://www.oracore.org Lastly, the Osteoarthritis and Cartilage journal, which publishes abstracts from the annual OARSI conference, can be found at http://www.oarsijournal.com/

In this very first episode of Hey OA, host Kerry Costello gives an introduction to the podcast and a preview of what's to come. We have some great guests lined up for the next few episodes so get excited! For more OA research news, check out OARSI.org and follow us on social media @OARSInews, @OARSI_YI, and @heyoapodcast. If you have any questions or comments, tag us and use the hashtag #heyoapodcast. Thanks for listening!