Circulation On The Run

This week please join guest author Adam Griesemer and Associate Editor and Digital Strategies Editor Maryjane Farr as they discuss the Review Article "Cardiac Xenotransplantation: Current State and Future Directions." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250707.102697

This week please join guest host Susmita Sahoo and author Huize Pan as they discuss the article "Atherosclerosis Is a Smooth Muscle Cell–Driven Tumor-Like Disease." Dr Pan and his coauthors are the recipients of the 2025 Joseph Loscalzo Award. This award recognizes the best basic/translational article published in Circulation in the preceding 12 months. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250629.645452

This week please join author Yuxiang Dai and Associate Editor Esther Lutgens as they discuss the article "Modified mRNA Treatment Restores Cardiac Function in Desmocollin-2–Deficient Mouse Models of Arrhythmogenic Right Ventricular Cardiomyopathy." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250623.661904

This week please join author Robert Clarke and Associate Editor Wendy Post as they discuss the article "Causal Relevance of Lp(a) for Coronary Heart Disease and Stroke Types in East Asian and European Ancestry Populations: A Mendelian Randomization Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250617.454324

This week please join author Nikolaus Marx as he discusses the article "Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250609.351110

This week please join author Brian Lindman and Executive Editor and Editorialist James de Lemos as they discuss the article "Cardiac Biomarkers in Patients With Asymptomatic Severe Aortic Stenosis: Analysis From the EARLY TAVR Trial" and the accompanying editorial "Biomarkers to Guide the Timing of Aortic Valve Replacement in Asymptomatic Aortic Stenosis: Where Do We Stand After Early TAVR?" For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250529.497472

This week please join author Varsha Tanguturi and Associate Editor Dharam Kumbhani as they discuss the article "Electronic Provider Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: A Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250528.505920

This week please join author André Zimerman and Associate Editor Amit Khera as they discuss the article "Intensive Lowering of LDL Cholesterol Levels With Evolocumab in Autoimmune or Inflammatory Diseases: An Analysis of the FOURIER Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250519.268826

This week please join author Milind Desai and Associate Editor Mark Link as they discuss the article "Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results From VALOR-HCM."  For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250512.476310

This week please join author Jarett Berry as well as Guest Editor and Editorialist Paul Thompson as they discuss the article "High-Volume Physical Activity and Clinical Coronary Artery Disease Outcomes: Findings From the Cooper Center Longitudinal Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250505.656863

This week please join author Bin Zhou and Associate Editor Zhao Wang as they discuss the article "Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250428.805646

This week please join author Signe Glargaard and Associate Editor Justin Ezekowitz as they discuss the article "A Randomized Controlled Trial of Thoracentesis in Acute Heart Failure." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250421.239148

This week please join author Emmanuel Stamatakis and Associate Editor Jarett Berry as they discuss the article "Dose Response of Incidental Physical Activity Against Cardiovascular Events and Mortality." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250414.213483

This week please join author Barry Borlaug and Associate Editor Torbjørn Omland as they discuss the article "Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250407.806254

This week please join author Josef Stehlik as he discusses the article "Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250331.87307

This week please join author Josefine Windfeld-Mathiasen and Associate Editor Ntobeko Ntusi as they discuss the article "Cardiovascular Disease in Anabolic Androgenic Steroid Users." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250324.957173

This week please join author Eric Rosenthal and Associate Editor Gerald Greil as they discuss the article "Covered Stent Correction for Sinus Venosus Atrial Septal Defects, an Emerging Alternative to Surgical Repair: Results of an International Registry." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20250317.309077

This week please join author Michael Zile and Associate Editor Justin Ezekowitz as they discuss the article "Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250307.892170

This week please join author Yugo Yamashita and Associate Editor Joshua Beckman as they discuss the article "Rivaroxaban for 18 Months Versus 6 Months in Patients With Cancer and Acute Low-Risk Pulmonary Embolism: An Open-Label, Multicenter, Randomized Clinical Trial (ONCO PE Trial)." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250303.648421

This week please join author Carl Johann Hansen and Associate Editor Mark Link as they discuss the article "Declining Trend of Sudden Cardiac Death in Younger Individuals: A 20-Year Nationwide Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250224.873552