Synopsis
man·i·fold /manfld/ many and various.
Episodes
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Rebecca Campbell on Identifying Serial Perpetrators, Rape Investigations and Untested Rape Kits – #18
05/09/2019 Duration: 01h37minDr. Rebecca Campbell is a Professor of Psychology at Michigan State University, whose research focuses on violence against women and children with an emphasis on sexual assault. Steve and Corey discuss her recent National Institute of Justice-funded project to study Detroit’s untested rape kits. Dr. Campbell describes the problem of untested kits and her work with police departments around the country to reduce the backlog. She explains how the use of the national CODIS database has led to sharply higher estimates of the proportion of rapes committed by serial perpetrators and how many rapists appear to be criminal “generalists”, committing a wide range of offenses. She describes the dynamics of sexual assault investigations, the factors that lead police to put more effort into investigating certain cases over others, and how common ways of questioning women can lead them to disengage from the process. Other topics include the incentives at work in law enforcement, the slow pace at which new research in DNA t
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Mark Moffett on the Life and Death of Human Societies – #17
22/08/2019 Duration: 57minSteve and Corey talk with Mark Moffett, Photographer and Research Fellow at the Smithsonian Institute, about his new book The Human Swarm: How our Societies Arise, Thrive and Fall. They discuss Mark’s view that being able walk into a cafe filled with others and not be attacked illustrates what makes human societies distinct and so successful. Mark explains why he is far more interested in questions about when war and other events occur than with traditional issues such as the genetic origins of human behavior. The three discuss Dehumanization and its Chimp equivalent, Dechimpanizeeization, and how they lead to the division of societies, friend turning against friend, and genocide. They discuss the conditions under which foreigners are embraced and whether the US might ever enter into a post-racial society where group differences don’t matter and immigrants are more easily accepted.ResourcesMark Moffett’s BioMark Moffett’s PhotographyThe Human Swarm: How Our Societies Arise, Thrive, and FallTranscript
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John Schulman: OpenAI and recent advances in Artificial Intelligence – #16
08/08/2019 Duration: 01h07minJohn Schulman is a research scientist at OpenAI. He co-leads the Reinforcement Learning group and works on agent learning in virtual game worlds (e.g., Dota) as well as in robotics. John, Corey, and Steve talk about AI, AGI (Artifical General Intelligence), the Singularity (self-reinforcing advances in AI which lead to runaway behavior that is incomprehensible to humans), and the creation and goals of OpenAI. They discuss recent advances in language models (GPT-2) and whether these results raise doubts about the usefulness of linguistic research over the past 60 years. Does GPT-2 imply that neural networks trained using large amounts of human-generated text can encode “common sense” knowledge about the world? They also discuss what humans are better at than current AI systems, and near term examples of what is already feasible: for example, using AI drones to kill people.ResourcesJohn SchulmanOpenAIBetter Language Models and Their Implications (GPT-2)Transcript
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Daniel Max on Writing a Literary non-Fiction Classic and Prion Diseases Then and Now – #15
25/07/2019 Duration: 01h16minDaniel Max, staff writer at The New Yorker and author of Every Love Story is A Ghost Story, a biography of David Foster Wallace, speaks with Corey and Steve about his first book, The Family that Couldn’t Sleep. The discussion covers the emerging genre of literary non-fiction, Daniel’s process of writing The Family that Couldn’t Sleep, and how he approached and gained the trust of the family at the heart of the story. Corey probes Daniel about how he handled the complex scientific characters, Carl Gajdusek and Stanley Prusiner, who led research into prion disease for 40 years. Daniel recounts how Shirley Glasse (now Lindenbaum) discovered how prions were transmitted through ritual cannibalism in Papua New, a critical step in solving the mystery of what causes of the disease, but how credit was given to Gajdusek. The three discuss the painfully slow pace of research and the inspiring story of a young couple, Eric Minikel and Sonia Vallabh, who have changed careers to dedicate their lives to finding a cure.Resou
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Stuart Firestein on Why Ignorance and Failure Lead to Scientific Progress – Episode #14
11/07/2019 Duration: 01h34sSteve and Corey speak with Stuart Firestein (Professor of Neuroscience at Columbia University, specializing in the olfactory system) about his two books Ignorance: How It Drives Science and Failure: Why Science Is So Successful. Stuart explains why he thinks that it is a mistake to believe that scientists make discoveries by following the “scientific method” and what he sees as the real relationship between science and art. We discuss Stuart’s recent research showing that current models of olfactory processing are wrong, while Steve delves into the puzzling infinities in calculations that led to the development of quantum electrodynamics. Stuart also makes the case that the theory of intelligent design is more intelligent than most scientists give it credit for and that it would be wise to teach it in science classes.ResourcesStuart FiresteinFailure: Why Science Is so SuccessfulIgnorance: How it drives scienceTranscript
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Joe Cesario on Political Bias and Problematic Research Methods in Social Psychology – #13
27/06/2019 Duration: 58minCorey and Steve continue their discussion with Joe Cesario and examine methodological biases in the design and conduct of experiments in social psychology and ideological bias in the interpretation of the findings. Joe argues that experiments in his field are designed to be simple but that in making experimental set ups simple researchers remove critical factors that actually matter for a police officer to make a decision in the real world. In consequence, he argues that the results cannot be taken to show anything about actual police behavior. Joe maintains that social psychology as a whole is biased toward the left politically and that this affects how courses are taught and research conducted. Steve points out the university faculty on the whole tend to be shifted left relative to the general population. Joe, Corey, and Steve discuss the current ideological situation on campus and how it can be alienating for students from conservative backgrounds.ResourcesJoseph Cesario’s LabA new look at racial dispariti
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James Cham on Venture Capital, Risk Taking, and the Future Impacts of AI – Episode #12
13/06/2019 Duration: 01h16minJames Cham is a partner at Bloomberg Beta, a venture capital firm focused on the future of work. James invests in companies applying machine intelligence to businesses and society. Prior to Bloomberg Beta, James was a Principal at Trinity Ventures and a VP at Bessemer Venture Partners. He was educated in computer science at Harvard and at the MIT Sloan School of Business.ResourcesJames ChamBloomberg BetaTranscript
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Joe Cesario on Police Decision Making and Racial Bias in Deadly Force Decisions – Episode #11
30/05/2019 Duration: 01h18minCorey and Steve talk with Joe Cesario about his recent work showing that, contrary to many activist claims and media reports, there is no widespread racial bias in police shootings. Joe discusses his analysis of national criminal justice data and his experimental studies with police officers in a specially designed realistic simulator. He maintains that evidence suggests that racial bias does exist in other uses force of force such as tasering but that the decision to shoot is fundamentally different and driven by facts about criminal context in which officers find themselves rather than race.ResourcesExample of officer completing shooting simulatorA new look at racial disparities in police use of deadly forceIs There Evidence of Racial Disparity in Police Use of Deadly Force? Analyses of Officer-Involved Fatal Shootings in 2015–2016Overview of Current Research on Officer-Involved ShootingsJoseph Cesario’s LabTranscript
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Ron Unz on the Subprime Mortgage Crisis, The Unz Review, and the Harvard Admissions Scandal – Episode #10
16/05/2019 Duration: 01h05minRon Unz is the publisher of the Unz Review, a controversial, but widely read, alternative media site hosting opinion outside of the mainstream, including from both the far right and the far left. Unz studied theoretical physics at Harvard, Cambridge and Stanford. He founded the software company Wall Street Analytics, acquired by Moody’s in 2006, and was behind the 1998 ballot initiative that ended bilingual education in California.ResourcesThe Unz ReviewThe Myth of American Meritocracy – How corrupt are Ivy League admissions?The Myth of American Meritocracy and Other EssaysTranscript
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Philosopher Sam Kerstein on the Morality of Genome Engineering, Inequality, and Star Trek – Episode #9
02/05/2019 Duration: 01h10minCorey and Steve speak with Samuel Kerstein, Professor of Philosophy and expert in Medical Ethics at the University of Maryland. They discuss the ethics of genome engineering and preimplantation embryo selection, and the inequality and narrowing of human diversity that might result from widespread adoption of these technologies. Among the topics covered: Why genome engineering at this time is immoral. Should we always pick the healthiest embryo? In the future will parents have a moral obligation to engineer their children? Will there be an arms race between countries to engineer their populations? Is Star Trek’s Khan a more advanced person (Steve) or just another smart psychopath (Sam) or both?ResourcesSamuel J. KersteinHow to Treat Persons by Samuel J. KersteinCRISPR Babies – Episode #1Transcript
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Sabine Hossenfelder on the Crisis in Particle Physics and Against the Next Big Collider – #8
18/04/2019 Duration: 01h04minHossenfelder is a Research Associate at the Frankfurt Institute of Advanced Studies. Her research areas include particle physics and quantum gravity. She discusses the current state of theoretical physics, and her recent book Lost in Math: How Beauty Leads Physics Astray.ResourcesThe Uncertain Future of Particle Physics (New York Times Article)Lost in Math: How Beauty Leads Physics Astray (Book)Transcript
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David Skrbina on Ted Kaczynski, Technological Slavery, and the Future of Our Species – Episode #7
04/04/2019 Duration: 01h14minDavid Skrbina is a philosopher at the University of Michigan. He and Ted Kaczynski published the book Technological Slavery, which elaborates on the Unabomber manifesto and contains about 100 pages of correspondence between the two which took place over almost a decade. Skrbina discusses his and Kaczynski’s views on deep problems of technological society, and whether violent opposition to it is justified.ResourcesDavid Skrbina’s Featured PublicationsPhotos of Ted KacynskiDavid Skrbina, Pen Pal of the Unabomber, on Ted Kaczynski’s PhilosophyTribe by Sebastian JungerJoe Rogan Experience #975 – Sebastian JungerTranscript
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John Hawks on Human Evolution, Ancient DNA, and Big Labs Devouring Fossils – Episode #6
21/03/2019 Duration: 54minHawks is the Vilas-Borghesi Distinguished Achievement Professor of Anthropology at the University of Wisconsin – Madison. He is an anthropologist and studies the bones and genes of ancient humans. He’s worked on almost every part of our evolutionary story, from the very origin of our lineage among the apes, to the last 10,000 years of our history.ResourcesJohn Hawks WeblogGhosts and Hybrids: How ancient DNA and new fossils are changing human origins (Research Presentation)Transcript
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Kaiser Kuo of Sinica on Modern China and US-China relations – Episode #5
07/03/2019 Duration: 01h17minKaiser Kuo is a host and co-founder of Sinica, a current affairs podcast originally based in Beijing. Sinica guests include prominent journalists, academics, and policy makers who participate in uncensored discussions about Chinese political, economic, and cultural affairs.ResourcesSinica PodcastPersonal Ties, Meritocracy, and China’s Anti-Corruption Campaign“MMG | Kaiser Kuo” by Meet the media Guru is licensed under CC BY-SA 2.0Transcript
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Ted Schultz on Ants, Emergent Behavior, and the Molecular Revolution in Systematics – Episode #4
21/02/2019 Duration: 45minCorey and Steve speak with Ted Shultz, research Entomologist at the Smithsonian National Museum of Natural History. Ted is an expert in Leaf Cutter Ant evolution and systematics. Topics discussed include evolution, systematics, the genetic basis of behavior, E. O. Wilson and small revolutions in science.ResourcesTed SchultzScience Magazine Table of Contents – December 9, 1994As flies to wanton boys are we to the gods (Seymour Benzer)The City Under the Back StepsTranscript
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Noor Siddiqui, Thiel Fellow, on Stanford and Silicon Valley – Episode #3
07/02/2019 Duration: 01h08minCorey and Steve interview Noor Siddiqui, a student at Stanford studying AI, Machine Learning, and Genomics. She was previously a Thiel Fellow, and founded a medical collaboration technology startup after high school. The conversation covers topics like college admissions, Tiger parenting, Millennials, Stanford, Silicon Valley startup culture, innovation in the US healthcare industry, and Simplicity and Genius.ResourcesNoor SiddiquiThiel FellowsTranscript
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Bobby Kasthuri & Brain Mapping - Episode #2
31/01/2019 Duration: 01h15minCorey and Steve are joined by Bobby Kausthuri, a Neuroscientist at Argonne National Laboratory and the University of Chicago. Bobby specializes in nanoscale mapping of brains using automated fine slicing followed by electron microscopy. Among the topics covered: Brain mapping, the nature of scientific progress (philosophy of science), Biology vs Physics, Is the brain too complex to be understood by our brains? AlphaGo, the Turing Test, and wiring diagrams, Are scientists underpaid? The future of Neuroscience.▶️ WATCH: Bobby Kausthuri & Brain Mapping — Episode #2ResourcesBobby Kasthuri BioThe Physicist and the Neuroscientist: A Tale of Two ConnectomesComputing Machinery and Intelligence by Alan M. TuringTranscript
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CRISPR Babies — Episode #1
24/01/2019 Duration: 22minCorey and Steve discuss news of gene edited babies in China, and the future of human genetic engineering.▶️ Watch: CRISPR Babies — Episode #1ResourcesGeneration CRISPR?He did it: He Jiankui talk at HKU conference on gene editingEconomist Radio podcast interview on Genomic PredictionTranscript
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Introductions — Episode #0
24/01/2019 Duration: 48minCorey and Steve, friends for almost 30 years, introduce each other to the audience.Caltech Traditions and Prankshttp://www.admissions.caltech.edu/exp...Steve’s blog, Information Processing http://infoproc.blogspot.comman·i·fold /ˈmanəˌfōld/ many and various.In mathematics, a manifold is a topological space that locallyresembles Euclidean space near each point.