The Science Hour

Messenger RNA-based vaccines have been used successfully to kick start the antibody production needed to fight Covid-19. Now the technology has been successfully used to encourage the growth of new bones to heal severe fractures. The technique seems to work far better than the current alternatives says Maastricht University’s Elizabeth Rosado Balmayor.Ivory smuggling continues to be a lucrative business for international criminal gangs, however, DNA techniques to trace where ivory seized by law enforcement authorities originates are now so accurate that individual animals can be pinpointed to within a few hundred miles. This says Samuel Wasser at the University of Washington, can be used as evidence against those ivory trafficking gangs.And we look at development in attempts to detect and weigh neutrinos, elusive subatomic particles essential to our understanding of the makeup of the universe. Physicist Diana Parno from Carnegie Mellon University takes us through the latest findings.Philologists have borrowed

The Wuhan Institute of Virology has been at the centre of a controversy surrounding the origins of the virus which caused the Covid-19 pandemic. The work of the lab's previously obscure division looking at bat coronaviruses has been the subject of massive speculation and misinformation campaigns. Journalist and former biomedical scientist Jane Qui has gained unique access to the lab. She has interviewed the staff there extensively and tells us what she found on her visits.And Tyler Starr from the Fred Hutchinson Institute in Seattle, has looked at a range of bat coronaviruses from around the world, looking to see whether they might have the capability to jump to humans in the future. He found many more than previously thought that either have or are potentially just a few mutations away from developing this ability.Nuclear fusion researchers at the 40-year-old Joint European Torus facility near Oxford in the Uk for just the 3rd time in its long history, put fully-fledged nuclear fuel, a mixture of hydrogen is

We’re 40 years into the AIDS pandemic, and even with massive public health campaigns, still, 1 ½ million become infected with HIV each year; about half that number die of its ravages. And a study just out shows that this well-understood virus can still take on more worrying forms as a new variant has been uncovered. Although the total number of cases involved is small, and the new variant is as treatable as earlier strains, the finding underlines that viruses can become more infectious and more virulent. Back in October 2020, before we had effective vaccines, 36 plucky volunteers agreed to be deliberately infected with SARS-CoV-2 in order to better understand the infection process and outcomes in what’s known as a human “challenge” trial. Dr. Chris Chiu from Imperial College reveals what they’ve learned now the results of the study are in. We’ll hear about a new plastic that’s stronger than steel and as many gardeners have long suspected, – spring-flowering has over many years been occurring earlier and ear

There are now a number of biological indicators for the potential development of long covid. Immunologist Onur Boyman of Zurich University Hospital and Claire Steves, Clinical Senior Lecturer at King’s College London strives to tell us how pinpointing these factors is now helping in the development of strategies to predict the syndrome and prepare treatment.The James Webb telescope has reached its final orbit. The years of planning, preparation and rehearsal seem to have paid off. The telescope is now ready to begin its mission of looking back into the early universe. BBC Science correspondent Jonathan Amos has followed the mission.The widely held view that human development was propelled by our ancestors developing a taste for meat is being questioned by a new analysis of the fossil record. Paleoanthropologist Andrew Barr of George Washington University suggests part of the reason for this assumption is the sampling method, actively looking for evidence to support the hypothesis.And Michael Boudoin of Lille

The effects of the Tonga eruption could be felt around the world, many heard the boom of a sonic shock, and tsunami waves travelled far and wide. Volcanologist Shane Cronin from the University of Auckland in New Zealand is one of only a handful of people to have landed on the tiny islands above the volcano where the eruption took place. Those islands have now sunk beneath the waves but Shane tells us what he found when he went there and how his findings could inform what happens next.Stephan Grilli from the School of Ocean Engineering at the University of Rhode Island joins us from Toulon in France where he felt the effects of the shockwave and Tsunami. He says the force of the shockwave drove those waves worldwide.The oceans have continued to warm, producing continuous record temperature rises for several years now. That’s the finding of Michael Mann of the University of Pennsylvania and author of The New Climate Wars. He says warming occurred last year despite the presence of global weather patterns which w

Studies using swabs from coronavirus patients seem to contradict earlier findings from cell cultures which showed Omicon replicated faster than earlier variants. As Benjamin Meyer from the centre for Vaccinology at the University of Geneva, explains there may be other reasons why omicron is spreading faster not just how quickly it reproduces.Predicting how the pandemic will develop is not possible, however predicting what individual mutations in the virus may develop and the impact they might have individually and collectively is getting closer, Cyrus Maher and Amalio Telenti of the biotech company Vir, have developed a way to model potential future viral mutations which they hope will now be used by many scientists worldwide looking to understand the virus.There are concerns that other viruses may be on the rise, bird flu in particular, which as Nicola Lewis of the Royal Veterinary College explains is now spreading to part of the world where it is not usually seen, and infecting other animals as well as bird

Now being produced in India CORBEVAX is grown in yeast in a similar way to several other widely available vaccines. The technology used to make it is far simpler and much more readily available than that used to produce mRNA vaccines. In theory, CORBEVAX could be produced cheaply in large quantities and go a long way to addressing the problems of Covid19 vaccine availability globally. It was developed by a team from Baylor College of Medicine in Texas including Maria Elena Bottazzi.Antibiotic-resistant superbugs are thought to have emerged in repose to the use of antibiotics, however, the discovery of a superbug living on the skin of hedgehogs has challenged this view. The superbug is thought to have been living with hedgehogs long before antibiotics were discovered. Jesper and Anders Larsen at the Danish State Serum Institute in Copenhagen explain.Modifying viruses, using them to infect or kill pest organisms is an attractive proposition. However, there are concerns over what might happen when they are relea

Studies from South Africa and the UK suggest Omicron may be a mild infection for the majority of people. Hospital admissions are down when compared with other variants. However, the virus is replicating at a much faster rate than earlier variants and is able to overcome vaccines to some extent. Cases studies so far have mainly been in young people. There is concern over what will now happen as Omicron spreads across Europe and the US where there are older unvaccinated populations. Anne von Gottberg from South Africa’s National Institute for Communicable Diseases tells us what early results from studies there show and discusses the implications. Typhoon Rai in the Philippines led to the loss of many lives and even destroyed buildings designed to resist such extreme weather events. Could more have been done either to predict the ferocity of the typhoon or to prepare for its impact? Liz Stephens, Associate Professor in Climate Risks and Resilience from the University of Reading discusses these issues.Beavers a

A study from Hong Kong university shows Omicron replicates 70 times faster than two earlier variants of the SARS-Cov-2 virus. Virologist Malik Peiris, explains how tests using cells from the wind pipe showed the dramatic difference, which supports observations of increased transmission. In contrast Omicron replicated less well than other variants on cells from dep in thre lung – offering some possibility that it may produce mild infections.Tornados in the US do not normally occur in December. The one which swept across Kentucky and 3 other states was fuelled by weather patterns likely to have been influenced by long term climate change says Geographer James Elsner of Florida State University.The Parker Solar probe continues its mission of flying closer and closer to the sun. Results just published show what the data the probe picked up when it dipped into the surrounding plasma. NASA’s Nicky Fox is our guide.And how many legs does a millipede have? Until now not as many as you might think. Entomologist Paul M

Which came first the volcano or the rain? Volcanic eruptions are known to influence global climate systems, even leading to the cooling of the planet. However local weather conditions can also influence the timing and ferocity of volcanic eruptions. As volcanologist Jenni Barclay explains rainwater can contribute to volcanic instability and even increase the explosiveness of eruptions.Syria has been experiencing civil war for more than 10 years. Many people have left including many of the country's scientists. We speak with 3 exiled Syrian scientists Shaher Abdullateef, Abdulkader Rashwani, and Abdul Hafez about their current work, which involves working with other academics and students in Syria sometimes remotely and sometimes directly.New findings from Chile reveal an unknown Tsunami emanating from an earthquake there in the 1700s. Historical records mention other ones, but not this one. Geoscientist Emma Hocking found the evidence in layers of sand.And we discuss the development of tiny robot-like structu

South Africa announced their discovery of the Omicron variant to the world as quickly as they could. The response from many nations was panic and the closure of transport links with southern Africa. Tulio de Oliveira who made the initial announcement and leads South Africa’s Centre for Epidemic Response and Innovation tells us this is now having a negative effect on the country, with cases rising but vital supplies needed to tackle the virus not arriving thanks to the blockade.Omicron contains many more mutations than previous variants. However scientists have produced models in the past which can help us understand what these mutations do. Rockefeller University virologist Theodora Hatziioannou produced one very similar to Omicron and she tells us why the similarities are cause for concern.Science sleuth Elisabeth Bik and Mohammad Razai, professor of Primary Care in St George’s University in London have just been awarded the John Maddox Prize for their campaigning investigations in science. Elisabeth is part

d dart Science in ActionDART is a space mission designed to hit a distant asteroid and knock it slightly out of orbit. It’s a test mission, a pilot project for a way of potentially protecting the earth from a stray asteroid. We hear from mission coordinators Nancy Chabot and Andy Rivkin, both from the Applied Physics Labs, APL, of Johns Hopkins University.A new kind of Covid-19 vaccine has successfully undergone preliminary tests. Tuebingen University’s Juliane Walz tells us about how it hopes to stimulate a longer lasting protective effect against the virus than current vaccines.And Haley Randolph of Chicago University sheds light on how our ancient ancestors’ exposure to viruses influences our susceptibility today.Historian Robert Schulmann gives us an insight into the significance of research notes by Albert Einstein and Michele Besso. Sold at auction in France the notes give an insight into the collaboration between the two scientists which led to much of what we now understand about the fundamentals of p

The political message from the COP meeting was a fudge over coal, but what does the science say? Surprisingly India seems to be on track to switch away from coal to renewables. We explore the apparent contradiction with Lauri Myllyvirta of the thinktank Centre for Research on Energy and Clean Air. Also a synchrotron for Africa, how such a project would give a boost to scientific development across the continent, with Marielle Agbahoungbata from the X-tech Lab in Seme City in Benin. Moriba Jah, who leads the Computational Astronautical Sciences and Technologies Group, at the University of Texas, in Austin, tells us what he saw when an exploding Russian satellite sent a shower of debris into the path of the International Space Station. And the animals that carry SARS-Cov-2, an analysis from Barbara Han of the Cary Institute of Ecosystem Studies in New York shows there are many more than previously thought.Image: A coal-fired power station in Nanjing in east China Credit: Feature China/Barcroft Media via Gett

Up to 8 percent of deer sampled in studies in the US were found to be infected with the SARS-Cov-2 Virus. Suresh Kuchipudi from the Department of Veterinary and Biomedical Sciences at Penn State University in the US says what they are seeing is a mixture of human to deer and deer to deer transmission of the virus. There is concern that its presence in animal reservoirs could lead to a new form of the virus emerging. Tropical forests and spread of zoonotic diseases And as the Cop26 meeting in Glasgow draws to a close we ask how global policy on climate will impact the spread of zoonotic disease. Spill over of possible pandemic pathogens from animals to humans occurs with the destruction of tropical forests in particular and can expose people to previously unknown zoonotic diseases such as Covid 19.Aaron Bernstein from the Coalition to Prevent Pandemics at the Source says healthcare initiatives designed to reduce the potential spread of such diseases need to be designed to work in tandem with conservation and c

Scientists in Switzerland have developed a system which uses solar energy to extract gases such as hydrogen and carbon dioxide from the air and turns them into fuels for transport. So far they have only made small quantities in experimental reactors, however they say with the right investment their alternatives to fossil fuels could be scaled up to provide a climate friendly way to power transport, particularly aviation and shipping. We speak to Aldo Steinfeld and Tony Patt from ETH Zurich and Johan Lilliestam from the University of Potsdam.And what will rises in global temperature mean where you live? An interactive model developed by Bristol University’s Seb Steinig shows how an average global rise of say 1.5C affects different regions, with some potentially seeing much higher temperatures than others. Dan Lunt – one of the contributing authors to this year’s IPCC report discusses the implications.We also look at racism in science, with problems caused by decisions on the naming of ancient bones more than 2

Just a few days before COP26 opens in Glasgow, the World Meteorological Organisation reported record greenhouse gas levels, despite a fall in CO2 due to pandemic restrictions. The UN Environment Programme’s Emissions Gap Report also revealed that current country pledges will only take 7.5% off predicted greenhouse gas emissions by 2030, well below the 55% needed to limit global warming to 1.5C. Worse still, many large emission producers are not on track to meet their countries’ pledges. Rachel Warren, Tyndall Centre for Climate Change Research, tells us the 1.5C limit is still achievable if we work in tandem with nature. Research by Sara Mikaloff-Fletcher, National Institute of Water and Atmospheric Research (NIWA), illustrates this. Her contribution to the WMO Greenhouse Bulletin revealed that New Zealand’s indigenous forests play a bigger role in absorbing carbon from the atmosphere than previously thought. Also on the programme, Abinash Mohanty, Council on Energy, Environment and Water, has been mapping cl

We’ve talked a huge amount the past 18 months, for obvious reasons, about the way that white blood cells protect us from infection. But red blood cells – it’s probably among the earliest things I learned in human biology that they’re simple bags for carrying oxygen around the body. But over recent years, immunologist Nilam Mangalmurti, University of Pennsylvania, has been finding several clues to challenge that dogma – including molecules on the surface of red blood cells known from other parts of the immune system. The Last Ice Area, home to the oldest and thickest ice in the Arctic, is expected to act as the last refuge for ice-dependent wildlife as the rest of the Arctic melts. Kent Moore, University of Toronto-Mississauga, tells us that the formation of a 3,000 square kilometre rift in the area means the ice is not as resilient as we once thought.Also on the programme, an obituary for the renowned Dutch climate scientist and physicist Geert Jan van Oldenborgh (October 22, 1961 – October 12, 2021), and, D

Since its introduction four decades ago, Spartina alterniflora, a salt-water cordgrass from the USA, has been spreading along China’s coasts. Today, it covers nearly half of the country’s salt marshes. As the UN Biodiversity Conference COP 15 kicks off in China, we look at how this invasive plant species threatens native species in protected coastal wetlands. Featuring Yuan Lin, East China Normal University, and Qiang He, Fudan University. In January 2020, Barney Graham and Jason McLellan teamed up to engineer a coronavirus spike protein that now powers the COVID-19 vaccines for Moderna, Pfizer, Johnson & Johnson and Novavax. They discuss their work, a next-generation vaccine using chicken eggs, and the future of pandemic preparedness. Also, a recent Nature survey reveals the extent of abuse against scientists who speak about COVID-19 publicly. Deepti Gurdasani, Queen Mary University of London, shares her experiences of trolling and online abuse and discusses the implications for academia and scientific d

n December 2020, China's Chang'e-5 mission returned to earth carrying rock samples collected from the moon – the first lunar samples to be collected since the American Apollo and Luna missions to the moon in the 1970s. Laboratory analysis has revealed that these are the youngest samples of rocks to be collected from the moon. Lunar geologist Katherine Joy explains what this tells us about the moon’s volcanic past. Also on the programme, a recent study reveals that the hepatitis B virus has been infecting humans for at least 10,000 years. Denise Kühnert from the Max Planck Institute for the Science of Human History shares what the evolution of the virus tells us about human evolution, as well as the rise and fall of civilisations. In the wake of Cyclone Shaheen, we also speak to Princeton University’s Ning Lin about how climate modelling can help us predict tropical storms in the Arabian Sea, and Fredi Otto joins us to discuss the 2021 Nobel Prizes for Science. Snails are a major enemy of gardeners around the

Since their discovery in the 1970s, artemisinin-based drugs have become the mainstay of treatment for malaria caused by the Plasmodium falciparum parasite. Researchers have identified artemisinin-resistant malaria parasites in Southeast Asia since the early 2000s, but now, there is evidence of resistance in Rwanda and Uganda. Dr Betty Balikagala of Juntendo University tells us how this resistance developed and what it means for managing malaria in Africa, which carries the greatest burden of malaria cases and deaths worldwide.We hear from some of the scientists from COVID Moonshot, a non-profit, open-science consortium which has just received key funding to develop affordable antivirals to stop SARS-CoV-2 in its tracks.Also on the programme, Dr Rakesh Ghosh from the University of California, San Francisco tells us how air pollution is contributing to 6 million preterm births globally each year, and Dr Catherine Nakalembe of the University of Maryland and Africa Lead for NASA Harvest returns to the programme a