Synopsis
Are you searching for stories to ignite your curiosity, teach you to perform better in life and career, inspire your mind, and make you laugh along the way? In this science podcast, Dr. Marie McNeely introduces you to the brilliant researchers behind the latest discoveries in science. Join us as they share their greatest failures, most staggering successes, candid career advice, and what drives them forward in life and science.
Episodes
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719: Studying the Sea through Shells, Skeletons, and Sediments - Dr. Abby Smith
31/07/2023 Duration: 39minDr. Abby Smith is an Associate Professor and Head of the Department of Marine Science at the University of Otago. In the lab, Abby is dedicated to studying shells and the animals that make shells. She is interested in how shells are made, what they are made out of, and how fast they grow. Abby also examines how shells break down over time and uses old shells to understand what the water was like in the past. Outside of science, Abby is a mother of two, and she keeps busy with family life and taking care of her kids. In her free time, she likes to watch cricket, knit, and cook. In particular, Abby has been experimenting lately with making different fruit jams and preserves. She Received her B.A. Degree in Geology and Biology from Colby College, her M.S. Degree in Earth, Atmospheric, and Planetary Sciences from the Massachusetts Institute of Technology, and her PhD in Earth Science from the University of Waikato. Abby joined us in this interview to share stories from her life and science.
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718: Making Molecular Movies of Complex Chemical Reactions in Live Cells - Dr. Antoine van Oijen
24/07/2023 Duration: 42minDr. Antoine van Oijen is a Distinguished Professor and Australian Research Council Laureate Fellow in the School of Chemistry at the University of Wollongong in Australia. The work Antoine does combines physics, chemistry, and biology. He develops new types of microscopes to visualize complex biochemical reactions at the level of individual molecules. In particular, his group is interested in how DNA is copied before a cell divides. Antoine is also doing research examining how bacteria acquire antibiotic resistance. Antoine and his family enjoy spending much of their free time exploring the beautiful beach and hiking in the wonderful parks nearby. Antoine received his MSc and PhD in Physics from Leiden University in the Netherlands, where his graduate work was recognized with the C.J. Kok prize for best doctoral thesis. Afterwards, he conducted postdoctoral research in Chemistry and Chemical Biology at Harvard University. Antoine served on the faculty at Harvard Medical School and Groningen University in the
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717: Developing Tools and Resources to Accelerate Neuroscience Discovery - Dr. Hongkui Zeng
17/07/2023 Duration: 42minDr. Hongkui Zeng is Executive Vice President and Director of the Allen Institute for Brain Science. She is dedicated to understanding how the brain is organized and how the different components of the brain work together to generate behaviors and functions. Hongkui and her colleagues examine the cellular basis of brain circuit formation and how those circuits produce function. They generate foundational tools and resources for the neuroscience community to help scientists around the world advance their research on neurological disease, potential treatments, and more. Living in the beautiful city of Seattle, Hongkui enjoys getting outside and exploring nature. This includes kayaking and hiking in the nearby mountains. When she’s at home, Hongkui likes to relax with a good book, listen to music, and indulge in watching shows and movies. She received her B.S. degree in biochemistry from Wuhan University and her PhD in molecular and cell biology from Brandeis University. Next, she conducted postdoctoral research
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716: Metabolic-Based Therapies As a Key Component in Treating Cancer and Other Diseases - Dr. Dominic D'Agostino
10/07/2023 Duration: 55minDr. Dominic D’Agostino is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida. He is also a Research Scientist Institute for Human and Machine Cognition. Dom’s lab develops technology that allows them to investigate the molecular, cellular, and physiological changes we experience in extreme environments, including those that would occur undersea, at high altitude, or in space. They are also designing and evaluating metabolic-based therapies as treatments for cancer and other diseases. Dom and his wife enjoy outdoor activities like going to the beach, hiking, kayaking, mountain biking, and horseback riding. They also do quite a bit of scuba diving together for his wife’s marine biology research on manta rays. Data collection has taken them to Indonesia, Fiji, Palau, Hawaii, and many other phenomenal dive sites. Dom received his B.S. in Nutritional Sciences and Biological Sciences as well as his Ph.D. in Neuroscience and Physiology at Rutgers Univ
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715: An Astrophysicist Studying the Elements of Galaxy Evolution - Dr. Molly Peeples
03/07/2023 Duration: 45minDr. Molly Peeples is an Aura Assistant Astronomer at the Space Telescope Science Institute in Baltimore, Maryland. Molly’s research is improving our understanding of galaxies and helping to reveal why galaxies are different from each other and how galaxies have changed over time. To do this, she traces the origins and fates of heavy elements that were all originally produced within stars. Examining where the elements end up gives us information on how gas flows into and out of galaxies. Molly also does modeling and runs simulations to better understand what is going on in the universe. There are a lot of great parks around Baltimore, so Molly likes getting outside to go hiking in her free time. She also enjoys cooking, reading, trying new cocktails, exploring new bars in town, and playing board games with friends. She received her B.S. in Physics from MIT and went on to complete her MS and PhD in Astronomy at Ohio State University. Molly was then awarded a Southern California Center for Galaxy Evolution Fello
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714: Tiny Technology with Big Impacts: Nanoparticles for Medicine, Energy, and the Environment - Dr. Christy Haynes
26/06/2023 Duration: 47minDr. Christy Haynes is the Elmore H. Northey Professor of Chemistry at the University of Minnesota. In Christy’s research group, they are working to develop new methods to monitor small quantities of important chemicals in complex environments. Their research also aims to develop new, safe nanomaterials for applications in human health and sustainable energy. When she’s not at work, Christy loves to go for a run around the lakes of Minneapolis and spend time with her spouse and two kids. Her son has an analytic mind and is interested in competitive sports, while her daughter enjoys art and music. She completed her undergraduate studies in Chemistry at Macalester College and received her MS and PhD in Chemistry from Northwestern University. Next, Christy was awarded a National Institutes of Health National Research Service Award Post-Doctoral Fellowship to conduct research at the University of North Carolina, Chapel Hill. She joined the faculty at the University of Minnesota in 2005. Christy has received many a
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713: Combining Chemistry and Biology to Develop New Research Tools and Therapeutics - Dr. David Liu
19/06/2023 Duration: 45minDr. David R. Liu is the Richard Merkin Professor and Director of the Merkin Institute of Transformative Technologies in Healthcare, vice-chair of the faculty at the Broad Institute of MIT and Harvard, the Thomas Dudley Cabot Professor of the Natural Sciences at Harvard University, and a Howard Hughes Medical Institute (HHMI) investigator. In addition, he is the founder or co-founder of several biotechnology and therapeutics companies, including Beam Therapeutics, Prime Medicine, Editas Medicine, Pairwise Plants, Exo Therapeutics, Chroma Medicine, Resonance Medicine, and Nvelop Therapeutics. David’s research integrates components of biological evolution with chemistry to enable the development of new types of therapeutics and to better study biology. Through chemistry, they can change the structure of a molecule in order to change its function in anticipated ways. They also harness the power of cycles of natural selection to evolve molecules with desired tailor-made properties. Outside of science, David’s hobb
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712: Dr. Lynne Maquat: Understanding Cellular and Molecular Pathways that Contribute to Human Disease
12/06/2023 Duration: 42minDr. Lynne Maquat is the J. Lowell Orbison Endowed Chair and Professor of Biochemistry and Biophysics in the School of Medicine and Dentistry, Director of the Center for RNA Biology, and Chair of Graduate Women in Science at the University of Rochester. Research in Lynne’s lab focuses on human diseases and what causes diseases in our cells. She is working to understand how cells function normally, determine what causes diseases, and develop treatments for diseases. In particular, she has been studying a process in cells that causes about one third of all inherited diseases, like cystic fibrosis and Duchenne muscular dystrophy, as well as one third of all acquired diseases, including cancer. Lynne has a Labrador retriever whom she loves taking on walks through the lovely parks and woods in Rochester, New York. She also enjoys exercising through yoga, lifting weights, and doing cardio. She received her BA in Biology from the University of Connecticut and her PhD in Biochemistry from the University of Wisconsin-M
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711: Researching RNA Regulation of Reproduction in Plants - Dr. Blake Meyers
05/06/2023 Duration: 42minDr. Blake Meyers is a Member Principal Investigator at the Donald Danforth Plant Science Center and a Professor in the Division of Plant Sciences at the University of Missouri. The focus of Blake’s research is on small RNAs in plants. His lab studies how RNAs are used to regulate the complex machinery of cells, particularly in the context of plant reproductive biology. When he’s not conducting research in the lab, Blake loves to travel both for work and for fun. Blake strives to balance his family life with his science, and he also enjoys reading cookbooks and experimenting in the kitchen at home. He received a B.A. in Biology from the University of Chicago, and went on to receive his MS and PhD in Genetics from the University of California, Davis. Afterwards, Blake completed postdoctoral fellowships at Dupont Genomics and at the University of California, Davis. Before accepting his current positions, Blake was the Edward F. and Elizabeth Goodman Rosenberg Professor and Chair of the Department Plant and Soil
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710: Investigating Carbon Capture Solutions from Cars to Coal-Fired Power Plants - Dr. Jennifer Wilcox
29/05/2023 Duration: 53minDr. Jennifer Wilcox is an Associate Professor in Chemical and Biological Engineering at the Colorado School of Mines and an Investigator within the Clean Energy Conversions Laboratory there. The research in Jen’s group focuses on carbon capture and trace metal pollution. On the carbon capture side, she tries to better understand and reduce CO2 emissions from coal and gas-fired power plants. In terms of trace metals, the most common source of trace metals like mercury in the fish we eat is burning coal in coal-fired power plants. Jen’s research examines how to capture trace metals and reduce their emission into the environment. Outside of science, Jen keeps busy spending time with her family including her husband and daughter. She also loves being active outdoors through hiking, running, and bicycling. She received her bachelor’s degree in mathematics from Wellesley College and her PhD in chemical engineering from the University of Arizona. She served on the faculty at the Worcester Polytechnic Institute and a
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709: Examining How the Brain Controls Our Thoughts and Actions to Reach Our Goals - Dr. Tim Buschman
22/05/2023 Duration: 43minDr. Tim Buschman is Associate Professor of Psychology and Neuroscience at Princeton University. He studies a process called cognitive control, a process in the brain that allows you to control your own thoughts and actions toward achieving your goals. There are a lot of factors that can influence cognitive control that must be integrated to direct your behavior. He uses animal models to better understand aspects of cognitive control, and his work has relevant applications for improving machine learning and artificial intelligence as well as developing new treatments for neurological diseases that impact cognitive control. When he’s not in the lab, Tim enjoys spending time outdoors with his family. In particular, they have been doing a lot of hiking, and Tim finds it a great activity for stimulating thoughts and drawing out his creativity. He received his B.S. in Biology from the California Institute of Technology, and Tim was then awarded a Postbaccalaureate Intramural Research Training Award (IRTA) to conduc
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708: Tales of Ion Detection: The Making of a Mass Spectrometry Mastermind - Dr. Charles Hohenberg
15/05/2023 Duration: 44minDr. Charles Hohenberg is a Professor of Physics at Washington University in St. Louis. In the lab, Charles does mass spectrometry of noble gases like Krypton and Xenon. He designed and built his own mass spectrometer which is one of the best in the world. With this instrument, Charles measures noble gas isotope ratios in various sources. A major focus is studying meteorite samples to understand early solar system processes. Charles has always been a tinkerer, and he often spends his free time working on various projects around the house. For example, one of Charles’ hobbies is woodworking. He built his own kitchen table and several other pieces of furniture. He received his PhD in Physics from the University of California, Berkeley and has been on the faculty at Washington University since 1970. Charles has received many awards and honors during his career, including election as Fellow of the Meteoritical Society and a Fellow of the St. Louis Academy of Science. He has been awarded the NASA Principal Investig
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707: Applying Analytical Chemistry Approaches to Better Understand Chemicals of Concern - Dr. Diana Aga
08/05/2023 Duration: 53minDr. Diana Aga is the Henry M. Woodburn Chair and a State University of New York (SUNY) Distinguished Professor in the Department of Chemistry at the University at Buffalo. She also serves as the Director of RENEW (Research and Education in eNergy, Environment and Water) Institute at the University at Buffalo. Diana is an environmental chemist. She studies sustainable agriculture and pollutants such as the “forever chemicals” (Per- and Polyfluorinated Substances (PFAS)) that we frequently encounter in our everyday lives. When it’s warm outside, Diana enjoys biking and hiking, and when it’s cold she spends more time indoors watching movies. Cooking is another one of Diana’s hobbies, and she is particularly fond of making Filipino food, creatively reusing leftovers, and recreating restaurant favorites at home. Diana received a B.S. degree in agricultural chemistry from the University of the Philippines, Los Baños and her PhD in analytical chemistry from the University of Kansas. Afterwards, she conducted postdoc
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706: Using Algorithms to Automate Decision-Making in Energy Management, Automobiles, and Manufacturing - Dr. Andrew Alleyne
01/05/2023 Duration: 58minDr. Andrew Alleyne is the Ralph and Catherine Fisher Professor in the Department of Mechanical Science and Engineering at the University of Illinois at Urbana-Champaign, as well as the Director of the National Science Foundation Engineering Research Center on Power Optimization for Electro-Thermal Systems (POETS) headquartered there. He is an engineer who works on control systems, which provide an automated way of making decisions. They take in relevant information and use algorithms to make correct decisions based on the information gathered. Andrew’s group designs algorithms that make the best decisions possible with the information available to keep systems stable and performing well. When not doing science, he spends much of his time with his wife and two sons. This translates to a lot of driving back and forth to soccer games, but also going on road trips and having fun together. Andrew grew up in Jamaica and came to the United States when he was in high school. He received his B.S. in Engineering degree
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705: Engineering New Enzymes and Predicting the Biochemical Activity of Proteins - Dr. Mary Jo Ondrechen
24/04/2023 Duration: 32minDr. Mary Jo Ondrechen is Professor of Chemistry and Chemical Biology at Northeastern University. In the lab, Mary Jo uses theory and computation to better understand how molecules work. In particular she works on enzymes which are proteins that catalyze chemical reactions. Mary Jo and her team also develop methods and theories to interpret genomic data, and they work on the computational side of drug discovery, helping medicinal chemists develop new drugs, treatments, and diagnostics. When she’s not at work, you can often find Mary Jo out running, tending to her vegetable garden, and cooking. She is also interested in herbs, spices, and medicinal plants. She earned her bachelor's degree in Chemistry from Reed College, and she was awarded her PhD in Chemistry and Chemical Physics from Northwestern University. Afterwards, Mary Jo completed a postdoctoral fellowship at the University of Chicago and subsequently a NATO Postdoctoral Fellowship at Tel-Aviv University in Israel. She joined the faculty at Northeaster
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704: Navigating the Seas of Change Studying Ocean Acidification and Marine Ecosystems - Dr. Tessa Hill
17/04/2023 Duration: 47minDr. Tessa Hill is an Associate Professor in the Department of Earth and Planetary Sciences at the University of California, Davis. She is part of the Bodega Ocean Acidification Research group there at the Bodega Marine Laboratory. Research in Tessa’s lab focuses on the ocean and the impacts of climate change on environments in the ocean in the past, present, and future. Outside of work, Tessa, her husband, and their two children spend a lot of time gardening, skiing, hiking, camping, and going on vacations together. Additionally, Tessa is a long-distance runner, so she enjoys running half and full marathons. Tessa received her B.S. in Marine Science from Eckerd College and her Ph.D. in Marine Science from the University of California, Santa Barbara. Next, Tessa was awarded a University of California President’s Postdoctoral Fellowship at UC Davis before joining the faculty there. Tessa has received many awards and honors during her career, including the Presidential Early Career Award for Scientists and Engin
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703: Using Chemical Genetics to Understand Cell Signaling Networks to Treat Human Diseases - Dr. Kevan Shokat
10/04/2023 Duration: 37minDr. Kevan M. Shokat is Professor in the Department of Cellular and Molecular Pharmacology at the University of California San Francisco, Professor in the Department of Chemistry at the University of California Berkeley, and an Investigator with the Howard Hughes Medical Institute. Kevan’s lab uses approaches from chemistry to address unsolved challenges and opportunities for discovery in biology and medicine. His goal is to apply chemistry to biology in the most impactful, interesting, and meaningful ways while pursuing his curiosity. The lab has been investigating key signaling proteins in diseases such as cancer to develop new treatments. When he’s not working, Kevan enjoys spending time with family, cycling with his friends, getting exercise, being out in nature, and reading biographies of scientists. Kevan received his B.A in chemistry from Reed College and his Ph.D. in organic chemistry from the University of California, Berkeley. Afterwards, he received a Life Sciences Research Foundation Fellowship to
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702: Dr. Adam Abate: Building High-Throughput Technology to Characterize Biological Systems
03/04/2023 Duration: 47minDr. Adam Abate is an Associate Professor in the Department of Bioengineering and Therapeutic Sciences at the University of California San Francisco. He is also a co-founder of the startup company Mission Bio. The overall goal of Adam’s lab is to make biology a new kind of computer science. It is important to characterize the state of biological systems in detail so you can manipulate the system successfully to get the outcome you want. For example, a disease represents a problem with a biological system, and you have to understand the system and know what to change to successfully cure a disease. Adam builds technologies, focusing on microfluidics technologies, to allow us to comprehensively characterize cells in a system. When he's not doing science, Adam and his wife have been working on various home improvement projects around the house, including painting and installing new lighting. The instant gratification of remodeling is a refreshing contrast to work in the lab. Adam received his B.A. in Physics from
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701: Studying and Preserving the Giant South American River Turtle and Other Species - Dr. Germán Forero-Medina
27/03/2023 Duration: 38minDr. Germán Forero-Medina is the Science and Conservation Director at the Wildlife Conservation Society Colombia. He also coordinates the projects for the conservation of freshwater turtles and tortoises in the Amazon Orinoco region. In his research, German studies the way animals live in nature and the problems that challenge their survival. He works with local communities and people in Columbia and across Latin America to find solutions for the environmental problems that affect the species they work with, as well as the people who co-exist with those species. Outside of his work, German loves spending time with his wife and twin sons. They enjoy traveling and exploring the outdoors together. German also likes playing basketball with friends on the weekends, and supporting his sons at their soccer and water polo matches. Germán completed his undergraduate training in Biology at the Universidad Nacional de Colombia. He received his MSc in Ecology from the Universidade Federal do Rio de Janeiro in Brazil and w
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700: Making Materials and Developing Devices for Extreme Environments - Dr. Debbie Senesky
20/03/2023 Duration: 45minDr. Debbie G. Senesky is an Assistant Professor in the Aeronautics and Astronautics Department at Stanford University. She is dedicated to creating materials that are tiny and tough enough to operate in extreme environments like outer space. They also study the impacts of space-like conditions on these materials. In particular, they leverage the properties of a class of nanomaterials called wide band gap semiconductors. The ceramic properties of these materials make them resistant to extreme temperature, chemical, and radiation environments, and Debbie’s research group fabricates these materials into small sensors and other devices. When Debbie isn’t working in the lab, you can find her hanging out with her husband, her daughter, and the family dog. Debbie also enjoys volunteering for the non-profit organization Scientific Adventures for Girls. This program engages elementary school students in activities to get them excited about STEM fields. She received her B.S. in Mechanical Engineering from the Universit