People Behind The Science Podcast - Stories From Scientists About Science, Life, Research, And Science Careers

  • Author: Vários
  • Narrator: Vários
  • Publisher: Podcast
  • Duration: 586:08:25
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Synopsis

Are you searching for stories to ignite your curiosity, teach you to perform better in life and career, inspire your mind, and make you laugh along the way? In this science podcast, Dr. Marie McNeely introduces you to the brilliant researchers behind the latest discoveries in science. Join us as they share their greatest failures, most staggering successes, candid career advice, and what drives them forward in life and science.

Episodes

  • 750: Studying How Cells Control Energy Use and Storage in Response to Hormones and Nutrients - Dr. Alan Saltiel

    04/03/2024 Duration: 40min

    Dr. Alan R. Saltiel is Distinguished Professor of Medicine and Pharmacology, Maryam Ahmadian Endowed Chair in Metabolic Health, Director of the Institute for Diabetes and Metabolic Health at UC, San Diego, and Director of the UCSD/UCLA Diabetes Research Center. Alan studies how cells that are involved in metabolism decide to take up and store energy, burn energy, or release energy for other cells to use in response to hormones, nutritional cues, and metabolic stress. He is particularly interested in studying cells in liver and fat tissues and better understanding the pathways involved in controlling the metabolic activities of these cells. When he’s not working, Alan enjoys exercise and physical activity, including tennis and occasionally basketball. He also likes to read fiction and non-fiction, spend time with friends and family, and experiment with cooking Mediterranean cuisine. He received his bachelor’s degree in zoology from Duke University, and his Ph.D. in biochemistry from the University of North Car

  • 749: Progressing Towards an Understanding of the Genes Contributing to Cancer Malignancy - Dr. Erica Golemis

    26/02/2024 Duration: 56min

    Dr. Erica Golemis is a Professor, Deputy Chief Science Officer, Co-Leader of the Molecular Therapeutics Program, and Director of the High Throughput Facility at the Fox Chase Cancer Center in Philadelphia. In addition, Erica is an adjunct faculty member at the University of Pennsylvania, Drexel University School of Medicine, and the Temple University Lewis Katz School of Medicine. For most of her scientific career, Erica has been conducting cancer research. Her recent work investigates why some cancers are particularly malignant. Erica’s research examines what genes cause cancer to change and progress, whether there are genes that can be targeted directly with different treatments to reverse this process, and if there is a therapeutic time window in which they could potentially reverse this process. When Erica finds free time, one thing she loves to do is read. She reads broadly and has been an avid reader since her early childhood. Erica also has fun attending theatre performances. There are multiple excelle

  • 748: Figuring Out the Functional Organization and Development of Cortical Circuits in the Brain - Dr. David Fitzpatrick

    19/02/2024 Duration: 39min

    Dr. David Fitzpatrick is Chief Executive Officer, Scientific Director, and Research Group Leader at the Max Planck Florida Institute for Neuroscience. The brain is important for so many aspects of our daily experiences, including what we perceive, what we think about, how we move, the decisions we make, and more. However, we still know relatively little about how the brain works and how it develops. David’s goal is to dive deep into these basic science questions of how the brain works and how it develops. When David isn’t hard at work at Max Planck, he spends his time hiking, biking, kayaking, and immersing himself in nature. He has also become a keen photographer, capturing captivating photos of the natural world and memorable moments in his life. David received his B.S. degree in Biology from Pennsylvania State University and his PhD in Psychology and Neuroscience from Duke University. He conducted postdoctoral research at the Medical University of South Carolina and then returned to Duke University as a me

  • 747: Conducting Research to Conserve Colorado's Rare Plants - Dr. Jennifer Ramp Neale

    12/02/2024 Duration: 39min

    Dr. Jennifer Ramp Neale is Director of Research and Conservation at the Denver Botanic Gardens. She is also an Adjunct Professor of Biology at the University of Northern Colorado and the University of Colorado Denver. The Denver Botanic Gardens is an accredited museum, a public nonprofit organization, and a research institution, so Jenny has a variety of different roles. She oversees the research conducted there, communicates their findings and the importance of science to different audiences, and works closely with land managers/owners to provide information on the local plants to help guide land management decisions. Jenny’s research focuses on applied conservation of plants, particularly rare and endangered species in Colorado. Outside of work, Jenny is a wife, mother, and outdoors enthusiast. She enjoys being active outdoors with her family playing soccer, skiing, camping, hiking, and generally having fun outside. Jenny’s passion for identifying plants and mushrooms is contagious, and as a result, her fam

  • 746: Investigating the Intersection of Nutrition and Bacterial Infection and Pathogenesis - Dr. Eric Skaar

    05/02/2024 Duration: 49min

    Dr. Eric Skaar is Director of the Institute for Infection, Immunology and Inflammation, Director of the Division of Molecular Pathogenesis, the Ernest W. Goodpasture Chair in Pathology, and Vice Chair for Research and a University Distinguished Professor in the Department of Pathology, Microbiology, and Immunology at Vanderbilt University. Eric is a bacteriologist who studies the impact of nutrition on infectious disease. His research examines how the food we eat affects our susceptibility to bacterial infection and how the bacteria that infect us get food once they are inside our bodies. He earned his B.S. in Bacteriology from the University of Wisconsin-Madison, his Ph.D. in Immunology and Microbial Pathogenesis from Northwestern University, and his M.P.H. in Epidemiology and Biostatistics from Northwestern University. Afterwards, he completed a postdoctoral fellowship in microbiology at the University of Chicago before joining the faculty at Vanderbilt in 2005. Eric has received numerous awards and honors

  • 745: Astrophysicist Radiating Enthusiasm for Research on Plasma Physics and Cosmic Rays - Dr. Ellen Zweibel

    29/01/2024 Duration: 38min

    Dr. Ellen Zweibel is the W. L. Kraushaar Professor of Astronomy and Physics, and the Vilas Distinguished Achievement Professor at the University of Wisconsin, Madison. Ellen is a theoretical astrophysicist who specializes in plasma astrophysics. Her studies examine electricity and magnetism in the cosmos, including phenomena like sun spots, the solar cycle, and high energy electromagnetic emissions (e.g. x-rays, gamma rays, and radio waves) from stars and galaxies. Ellen’s interests outside of science include creative writing, art, and exercise. She has recorded her thoughts and sketches in a journal since 1977, and drawing is a wonderful way for Ellen to see details in her surroundings that she might otherwise miss. In addition, Ellen has explored her artistic side through sculpting clay and painting. As far as exercise, Ellen runs at least 45 minutes every day. She received her bachelor’s degree in Mathematics from the University of Chicago and her PhD in Astrophysical Sciences from Princeton University. El

  • 744: Innovating Drug Discovery with Novel Approaches to Target Disease-Causing Proteins - Dr. Ryan Potts

    22/01/2024 Duration: 42min

    Dr. Ryan Potts is VP of Research and Head of the Induced Proximity Platform at Amgen that works on ways to bring two or more molecules in close proximity to each other to tackle drug targets that are currently considered “undruggable.” Ryan conducts early-stage research to discover new high-impact medicines for serious diseases that have a high unmet medical need. Their work examines biological pathways, drug targets, disease drivers, and new ways to create drugs that have the desired effects. He also leads Amgen’s Research & Development Postdoctoral Fellows Program. Outside of science, Ryan enjoys spending quality time with his family and his kids. They enjoy exploring the natural world, hiking, and exploring the nearby Santa Monica Mountains and local beaches. Ryan is also an avid traveler and sports fan. Ryan received his BS in biology from the University of North Carolina at Chapel Hill, and he was awarded his PhD in cellular and molecular biology from UT Southwestern Medical Center. After completing

  • 743: Advancing Tissue Engineering, Drug Discovery, and Drug Delivery - Dr. Pankaj Karande

    15/01/2024 Duration: 40min

    Dr. Pankaj Karande is an Associate Professor in Chemical and Biological Engineering at Rensselaer Polytechnic Institute. Pankaj was trained as a chemical engineer, and his research aims to apply engineering approaches and technology to solve problems in biology and healthcare to improve the quality and quantity of human life. Projects in his lab span areas such as drug discovery, drug delivery, biomaterials, diagnostics, and more. When he’s not working, Pankaj loves to cook, and experimenting with different recipes has been a great way to relieve stress. He was awarded his B.S. in Chemical Engineering from Mumbai University Institute of Chemical Technology and his Ph.D. in Chemical Engineering from the University of California, Santa Barbara. Pankaj was awarded an Anna Fuller Postdoctoral Fellowship in Molecular Oncology, and he conducted postdoctoral research in the Center for Cancer Research at Massachusetts Institute of Technology before joining the faculty at Rensselaer. Pankaj has received a variety of a

  • 742: Studying Hair Follicles and Skin to Better Understand Tissue Development and Regeneration - Dr. Claire Higgins

    08/01/2024 Duration: 41min

    Dr. Claire Higgins is a Reader (faculty) in Tissue Engineering and Regenerative Medicine in the Department of Bioengineering at Imperial College London. She is also President of the European Hair Research Society and Vice President of the Institute of Trichologists, a professional association for researchers who study the hair and scalp. Claire teaches and conducts research in the areas of tissue engineering and regenerative medicine. She uses skin and hair follicles as models to better understand how tissues respond to injury, heal wounds, and repair after disease. Outside of science, making pottery has been one of Claire’s favorite pastimes since she took her first classes as a postdoc. She enjoys making items like bowls, vases, and lamp bases on her pottery wheel in her studio during her free time. Claire received her B.Sc. in natural sciences and her PhD in skin developmental biology from Durham University in England. Afterwards, she conducted postdoctoral research at Columbia University. She worked as an

  • 741: Dr. Ariel Furst: Engineering Microbes to Improve Equity in Human and Environmental Health

    01/01/2024 Duration: 42min

    Dr. Ariel Furst is the Paul M. Cook Career Development Professor in the Department of Chemical Engineering at Massachusetts Institute of Technology (MIT). In her research, Ariel has been using microbes to address problems surrounding human health, environmental remediation, and sustainability. Her lab focuses on energy equity by developing  new technologies that are accessible to people who haven’t had access to technology but are negatively impacted by it. She is also working towards energy justice by developing technology and approaches to remediate prior harms to marginalized communities. In her free time, Ariel and her husband enjoy experimenting with new recipes in the kitchen. She also likes to spend time outdoors hiking, jogging, and doing fun activities like apple picking with her lab members. She received her B.S. degree in chemistry from the University of Chicago and her PhD in chemistry from the California Institute of Technology. Afterwards, she was awarded a Beckman Foundation Postdoctoral Fellow

  • 740: Targeting Complex Sugars on Cell Surfaces to Treat Multiple Sclerosis and Cancer - Dr. Michael Demetriou

    25/12/2023 Duration: 41min

    Dr. Michael Demetriou is Director of the National Multiple Sclerosis Society Designated Comprehensive Care Clinic, Professor of Neurology, and Chief of the Division of Multiple Sclerosis and Neuroimmunology at the University of California, Irvine (UCI) School of Medicine. In his research, Mike studies the biological roles of complex sugars called glycans. Glycans are mostly found outside of cells and on cell surfaces. They form a dense forest around the surface of cells and can interact with other proteins to regulate cellular function through interactions with other cell surface proteins. Mike’s lab is interested in how these cell surface glycans influence biology and disease, particularly in autoimmune diseases like multiple sclerosis (MS) and in diseases like cancer where there are commonly abnormalities in these glycans. Mike is also a big fan of the Toronto Maple Leafs hockey team. While he doesn’t play hockey himself anymore, he loves watching professional hockey games and seeing the Maple Leafs play wh

  • 739: Studying Cell Division to Better Understand and Improve Cancer Therapies - Dr. Beth Weaver

    18/12/2023 Duration: 38min

    Dr. Beth Weaver is a Professor in the Department of Cell and Regenerative Biology and the Department of Oncology/McArdle Laboratory for Cancer Research at the University of Wisconsin-Madison School of Medicine and Public Health. She is co-Leader of the Developmental Therapeutics Program at the University of Wisconsin Carbone Cancer Center. Beth studies a group of commonly used chemotherapy agents to better understand how they work, who will respond to these treatments, and how to make resistant tumors more sensitive to these drugs. Outside of work, Beth enjoys spending time with her family. She, her husband, and their two children enjoy making fun group Halloween costumes, and she also brings this creativity into entertaining and hosting themed parties. Beth received her B.S. in biochemistry from Brown University and her Ph.D. in biomedical sciences from the University of California, San Diego. Afterwards, Beth conducted postdoctoral research at the Ludwig Institute for Cancer Research before joining the facu

  • 738: Combining Geology and Microbiology to Investigate Modern and Ancient Microbes - Dr. Magdalena Osburn

    11/12/2023 Duration: 49min

    Dr. Magdalena Osburn is an Associate Professor in the Department of Earth and Planetary Sciences at Northwestern University. Maggie's research brings together microbiology and geology to understand biological activity in different environments in the past and present. She studies unique microbes that live in extreme environments like deep mines, hot springs, and caves. When she’s not working, Maggie likes to go hiking, backpacking, and generally be outside exploring nature. When she’s able to get away, she loves going on road trips to enjoy the splendor of the mountains in Montana. At home, Maggie also spends her time doing yoga, running, and knitting. She received her bachelor’s degree in Earth & Planetary Sciences and Environmental Studies from Washington University in St. Louis. Afterwards, she enrolled in graduate school at the California Institute of Technology where she earned her M.S. and Ph.D. degrees in geobiology from the Division of Geological and Planetary Sciences. Next, Maggie conducted post

  • 737: Investigating the Mechanics of How Cells Move in Cancer and the Immune System - Dr. Erdem Tabdanov

    04/12/2023 Duration: 54min

    Dr. Erdem Tabdanov is Assistant Professor in the Department of Pharmacology at Penn State College of Medicine and also a Member of the Penn State Cancer Institute. He studies the mechanical and structural aspects of cells to better understand how cells physically move, sense their environments, and accomplish their various functions. This is very relevant to cancer biology and understanding the immune system. Some of Erdem’s hobbies outside of science include working out at the gym, calligraphy, sketching, digital art, and other visual arts. He is also considering adopting a cat. His interest in digital art emerged from his desire to put the story of his research together in compelling figures and schematics for journal articles. He received his bachelor’s degree in biotechnology and his MSc in chemistry and molecular and cellular biotechnology from Lomonosov Moscow State Academy of Fine Chemical Technology (MITHT). He was awarded his PhD in cancer research from L'Institut Curie in Paris. Afterwards, Erdem co

  • 736: Studying How Food Influences Our Health and Behavior - Dr. Alexis Wood

    27/11/2023 Duration: 45min

    Dr. Alexis “Lekki” Wood is Associate Professor at USDA/ARS Children's Nutrition Research Center in the Division of Pediatrics-Nutrition at Baylor College of Medicine. Research in Lekki’s lab aims to better understand how food influences our health. She examines the full chain of changes that occur from the moment food is put into our mouths, trough digestion and absorption of particular molecules, to where those molecules go and how they affect our organs. Outside of work, you can find Lekki working out at the gym and spending quality time with her two children and their German shepherd. She is also a Lego builder and a competitive Pokemon card player along with her son. She received her BSc with honors in Psychology and from the University of Warwick. Afterwards, she completed her Postgraduate Certificate in Education at the University of Cambridge. Lekki enrolled in graduate school at King’s College London where she earned her MSc in social, genetic, and developmental psychiatry and her PhD in statistical g

  • 735: Growing Our Understanding of the Development, Regeneration, and Evolution of Teeth - Dr. Gareth Fraser

    20/11/2023 Duration: 01h11min

    Dr. Gareth Fraser is an Associate Professor in the Department of Biology at the University of Florida. Gareth is a developmental biologist interested in how things form during development, how they are recreated during regeneration, and how features develop and persist on evolutionary timescales. His lab typically examines these questions looking at oral teeth and dermal denticles (tooth-like structures) in unusual fish like pufferfish, hammerhead sharks, and ghost sharks (chimaera). When he’s not working, Gareth enjoys being outside in nature, playing soccer, scuba diving, and hunting for fossils in the creek near their home. He and his two young daughters have also been having fun exploring the mysterious realm of cryptozoology and reading books about monsters. Gareth received his bachelor’s degree in palaeobiology and evolution from the University of Portsmouth, his master’s degree in evolutionary biology and systematics from the University of Glasgow, and his PhD in evolutionary developmental biology from

  • 734: Examining the Role of Metabolism in Cancer and Response to Cancer Treatment - Dr. Rachel Perry

    13/11/2023 Duration: 45min

    Dr. Rachel Perry is Assistant Professor of Medicine (Endocrinology) and of Cellular and Molecular Physiology at the Yale University School of Medicine. Rachel’s scientific training focused on how our bodies use nutrients to stay healthy and what goes wrong in diseases like obesity and diabetes. In her current lab, she applies this background to better understand how changes in metabolism (nutrient supply) may affect cancer and how our bodies respond to cancer treatments. In her free time, Rachel enjoys spending time with her family, playing with their Labradoodle puppy, and going on walks in the fantastic fall weather. She is also an avid home chef, and she applies her scientific precision to prepare delicious meals for friends and family. She was awarded her B.S. in Biomedical Engineering and her Ph.D. (with Distinction) in Cellular & Molecular Physiology from Yale University. Afterwards, she remained at Yale for postdoctoral training in internal medicine and endocrinology, and she joined the Yale facult

  • 733: Using Microbes to Sustainably Produce Valuable Chemicals and Degrade Toxic Compounds - Dr. Susie Dai

    06/11/2023 Duration: 39min

    Dr. Susie Dai is an Associate Professor in the Department of Plant Pathology and Microbiology at Texas A&M University. She is also Director of the Biomonitoring Program in the Iowa State Hygienic Laboratory, leading the Iowa Statewide Biomonitoring public health surveillance. Susie works at the interface of chemistry and biology, and her research leverages microorganisms like bacteria and fungus to synthesize chemicals of value or degrade poisonous chemicals. This work has important applications for developing sustainable methods to produce chemicals and breaking down dangerous chemicals that are very stable. In addition, Susie’s work also includes biomonitoring where they examine exposure to toxic chemicals from private wells and other environmental sources. When she’s not at work Susie enjoys reading and hanging out with her family, including her two wonderful daughters. Susie received her BS degree in Chemistry from Fudan University, and her PhD in Chemistry from Duke University. Afterwards, she conduc

  • 732: Applying Molecular Biology Tools to Characterize Genes and Enhance Crop Species - Dr. Ralph Dewey

    30/10/2023 Duration: 46min

    Dr. Ralph Dewey is the Philip Morris Professor of Crop and Soil Sciences and Adjunct Professor of Plant and Microbial Biology at North Carolina State University (NCSU). Ralph uses the tools of molecular biology to identify and characterize genes of agronomic importance in crop species. When possible, he and his team alter those genes in ways that add value to the crop above and beyond what can be attained with traditional breeding approaches. Ralph and his team have done important work on the genetics of tobacco plants to decrease the hazards of smoking for people who still smoke. When Ralph has free time, he enjoys hanging out with his wife at their nearby beach condo and also watching college sports (particularly football and basketball). In addition, Ralph is working on writing his first novel. He was awarded his B.S. degree in biology from Utah State University, followed by his M.S. and Ph.D. in Crop Science from North Carolina State University. Afterwards, Ralph received an NSF Postdoctoral Research Fell

  • 731: Investigating the Mechanisms of Signaling and Regulation in Protein Complexes - Dr. Denise Okafor

    23/10/2023 Duration: 36min

    Dr. C. Denise Okafor is an Assistant Professor of Biochemistry and Molecular Biology, and of Chemistry at Pennsylvania State University. Many of the medications we take work by binding to a particular target and either turning off whatever is causing a problem or turning something on that is not working correctly. Denise’s research examines how small molecules like drugs find and interact with the targets they are supposed to interact with. She is particularly interested in proteins that can be turned on or off by the small molecules/drugs that they bind with. While science is a large part of Denise’s life, she also enjoys reading and writing fiction. Lately, she has been spending much of her free time with her kids, learning dances from Youtube videos and hanging out together. She received her B.S. in biomedical chemistry from Oral Roberts University and was awarded her M.S. in chemistry and a Ph.D. in biochemistry from Georgia Institute of Technology. Afterwards, Denise was selected to complete an Instituti

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