Labanimal

3 Minute 3Rs February 2019

Informações:

Synopsis

This is the February episode of 3-Minute 3Rs, brought to you by the North American 3Rs Collaborative (www.na3rsc.org, the NC3Rs (www.nc3rs.org.uk), and Lab Animal (www.nature.com/laban) The papers behind the pod: 1. 3D-printed Wash Station with Integrated Anesthesia Delivery Manifold for High-throughput Depilation of Laboratory Mice. https://bit.ly/2IpGrAP 2. DeepSqueak: a deep learning-based system for detection and analysis of ultrasonic vocalizations .https://go.nature.com/2tupSJK 3. Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline. https://go.nature.com/2RgnoYw [NA3RsC] Depilation (hair removal) is needed for many procedures done with laboratory mice, including surgery and imaging. Commercial depilatory creams are a safe, efficacious, and often-used method to achieve this hair removal. However, the use of these creams tends to be messy and time consuming, and wide procedural variation exists between laboratories. Furthermore, mice are generally under anesthesia during dep