Labanimal

This is the April episode of 3-Minute 3Rs, brought to you by the North American 3Rs Collaborative (www.na3rsc.org), the NC3Rs (www.nc3rs.org.uk), and Lab Animal (www.nature.com/laban) Source papers: 1. Characterizing Sources of Variability in Zebrafish Embryo Screening Protocols. https://bit.ly/2VP8njP 2. Effective chair training methods for neuroscience research involving rhesus macaques. https://bit.ly/2V7NOSv 3. AutonoMouse. https://bit.ly/2VP8tbb. Video: https://www.youtube.com/watch?v=6d7ctvj953M [NA3RsC] The zebrafish embryo, considered to experience little or no pain or distress, has been investigated as a humane replacement to the adult fish and adopted for chemical characterization and hazard assessments. The Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT) initiative was developed by the NTP NICEATM to address inconsistent test guidelines and identify sources of variability for zebrafish embryo-based assays. The goals included gathering input from zebrafish investigato