Manifold

This is a two-part episode. The first ~30m covers the most important 2025 breakthroughs in polygenic embryo screening, while the second 30m focuses specifically on AI capabilities at the frontier of human knowledge. Both segments make predictions for 2026 and beyond.Links:Chinese billionaires, Philo-semitism, and the Chosen embryos:https://x.com/hsu_steve/status/2000206116823675078My talk from Reproductive Frontiers 2025 in Berkeley:https://www.youtube.com/watch?v=n64rrRPtCa8Previous episodes on frontier AI capabilities in math and theoretical physicshttps://www.manifold1.com/episodes/theoretical-physics-with-generative-ai-101https://www.manifold1.com/episodes/ais-win-math-olympiad-gold-prof-lin-yang-ucla-97Chapter Markers:(00:00) - Introduction (02:22) - Advancements in Polygenic Prediction of Human Traits (03:20) - Polygenic Risk Scores in Healthcare (08:15) - Embryo Selection and IVF (20:37) - Public Perceptions: billionaires and FOMO (31:40) - AI advances in 2025: High end capabilities and use of AI at th