The Life Scientific

AP De Silva on building molecular fluorescence sensors for healthcare

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Synopsis

From humble beginnings in his native Sri Lanka, to a more than 40 year academic career at Queen’s University Belfast, Prof. AP (Amilra Prasanna) De Silva’s research into molecular photosensors has led to a pioneering career in that’s evolved from chemistry to medical diagnostics on one hand, to information processing on the other.Prof. De Silva challenged cultural expectations and overcame the lack of opportunities in chemistry that were available in Sri Lanka in the early 1970s. He first moved to Belfast to pursue research in photochemistry at Queen’s University. Inspired by his grandmother’s struggle with high blood pressure he engineered a unique sodium photosensor by marrying fluorescent molecules with chemical receptors. As a result of his international collaborations, a commercial, portable sensor was developed to detect salts and minerals in the blood. Its speed of analysis has since saved countless lives and improved healthcare around the world. AP talks to Jim Al-Khalili about his passion for enginee