Sausage Of Science

SoS 250: Jake Aronoff's incredible journey into aging (of immune cells)

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Synopsis

Jake Aronoff is a human biologist studying immune function and aging from an evolutionary and ecological perspective. During his PhD, he studied how stress and social inequality impacts inflammation and immunosenescence in the Philippines and US. He is currently a postdoctoral researcher at ASU studying inflammation and aging with Ben Trumble and the Tsimane Health and Life History Project. These studies focus on the development of chronic inflammation in later life (inflammaging), the links between metabolic and immune function (immunometabolism and meta-inflammation), and the relationship between infections, inflammation, and brain aging. His research also utilizes life history theory and energetic trade-offs to understand complex changes in biological functioning in later life, like the simultaneous occurrence of inflammaging and immunosenescence. ------------------------------ Find the paper discussed in this episode: Aronoff, J. E., Trumble, B. C. (2025). An evolutionary medicine and life history persp