Rnz: Our Changing World

New insights from an old vaccine

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Synopsis

Since the 1800s, tuberculosis (TB) has been responsible for an estimated 1 billion deaths. In New Zealand today, we don’t get many cases of TB, but worldwide it is the leading infectious disease killer. In the early 1900s a TB vaccine was developed. Called the BCG vaccine, it’s still used today. While it is the best TB vaccine we have, it’s not actually great at preventing TB infection, only providing some protection for the youngest of patients. However, scientists have discovered that the BCG vaccine can boost people’s immune systems in other ways. Now researchers at the Malaghan Institute in Wellington are investigating these findings further. Sign up to the Our Changing World monthly newsletter for episode backstories, science analysis and more.Guests:Dr Kerry Hilligan, Malaghan InstituteRebecca Palmer, Malaghan InstituteLearn more:In 2017, Alison Ballance reported on the looming antimicrobial resistance crisis, with drug-resistant TB part of the problem.Other Our Changing World episodes about research a