The Knowledge Project: A Farnam Street Podcast

#217 Josh Wolfe: Human Advantage in the World of AI

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Synopsis

While Silicon Valley chases unicorns, Josh Wolfe hunts for something far more elusive: scientific breakthroughs that could change civilization. As co-founder and managing partner of Lux Capital, he's looking for the kind of science that turns impossible into inevitable. Josh doesn’t just invest in the future—he sees it coming before almost anyone else.    In this conversation, we explore:  The rapid evolution of AI and potential bottlenecks slowing its growth  The geopolitical battle for technological dominance and rise of sovereign AI models  How advances in automation, robotics, and defence are shifting global power dynamics  Josh's unfiltered thoughts on Tesla and Elon Musk  AI's revolution of medical research  Parenting in a tech-dominated world  How AI is forcing us to rethink creativity, intellectual property, and human intelligence itself  Why the greatest risk isn't AI itself—but our ability to separate truth from noise    Despite the challenges ahead, Josh remains profoundly optimistic about