BEaTS Research Radio's Podcast

Omar Moghrabi from the University of Ottawa interviews Dr. Marceline Côté about using Sphingosine Kinase (SK) Inhibitors to treat enveloped viruses like Ebola. Dr. Côté is an associate professor at the University of Ottawa and the director of the Centre for Infection, Immunity, & Inflammation, where her research and practice involve antiviral treatments. In this episode, Dr. Côté weighs in on the emerging research that suggests that the use of SK inhibitors may be the future of broad-spectrum antiviral treatments. Omar and Dr. Côté discuss the mechanism, breadth, and safety of SK inhibitors in detail and the future of this post-entry approach to viral combat. Learn more: https://www.uottawa.ca/faculty-medicine/dr-marceline-cote0:03 | Introduction to the speaker1:04 | Lay Summary/intro to the topic1:54 | How do viruses like Ebola enter cells in the first place?4:50 | What are sphingosine kinases, and why are they such a good target for blocking viruses?6:00 | How effective is this approach across these vir