Sci Guys

For the first time ever we’ve used CRISPR  to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Follow the SCI GUYS @notcorry / @jampkin / @lukecutforth References & Further Reading https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/ https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis https://luxturna.com Gene Therapy https://www.nature.com/articles/d41586-018-06195-6 https://www.nature.com/articles/s41587-020-0493-4 https://www.nature.com/articles/s41573-019-0012-9 The EDIT-101 Trial ht

In this spooky episode of Sci Guys we explore the life of Johann Konrad Dippel - a mad scientist that some credit as the inspiration for Mary Shelley’s Dr Frankenstein… Despite the pack of any evidence. You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Follow the SCI GUYS @notcorry / @jampkin / @lukecutforth References & Further Reading Johann Konrad Dippel https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1034731/?page=5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1034731/?page=5 https://publishing.rcseng.ac.uk/doi/pdf/10.1308/147363513X13500508916973 Alchemy & Frankenstein https://www.britannica.com/topic/alchemy/Modern-alchemy https://www.britannica.com/topic/Frankenstein

You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Follow the SCI GUYS @notcorry / @jampkin / @lukecutforth References & Further Reading Scientific Studies & Papers https://www.science.org/lookup/doi/10.1126/science.1250830 https://www.sciencedirect.com/science/article/abs/pii/S0165178116301524?via%3Dihub https://journals.sagepub.com/doi/10.1177/0963721419884309 News & Magazine Articles https://www.bbc.com/news/science-environment-28130690.amp https://www.scientificamerican.com/article/why-boredom-is-anything-but-boring/ https://www.newyorker.com/culture/annals-of-inquiry/what-does-boredom-do-to-us-and-for-us

Can trees talk to each other? It turns out they might be able to, using fungi… This week, we discuss the Wood Wide Web that most of the world’s plants use to help them survive! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Follow the SCI GUYS @notcorry / @jampkin / @lukecutforth References & Further Reading Fungi https://www.livescience.com/amp/53618-fungus.html https://www.britannica.com/science/fungus/Mycorrhiza Plants https://www.britannica.com/plant/tree https://www.britannica.com/science/forest Mycorrhizal Networks https://www.sciencedirect.com/science/article/pii/B9780123739445003278 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802747/ https://www.bbc.com/news/science-environment-48257315.amp

Uterus transplants are on the verge of becoming a common surgery for cis women, but one of the first women to ever receive this kind of surgery wasn’t cis… The life of Lilli Elbe, one of the first women to receive gender affirming surgery, has been romanticised and repackaged as a tender tragedy - but her real story is far more interesting & upliftng. You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod Follow the SCI GUYS @notcorry / @jampkin / @lukecutforth References & Further Reading Transplants https://www.britannica.com/science/transplant-surgery/Organ-transplants https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778785/ https://www.nhsbt.nhs.uk/who-we-are/a-history-of-donation-transfusion-and-transplanta

What would you do if you found an animal that, with a little help, could potentially live forever? Worship it as a God? What could go wrong? That’s exactly what we’re digging into this week! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Lobsters https://www.britannica.com/animal/lobster https://www.smithsonianmag.com/science-nature/dont-listen-to-the-buzz-lobsters-arent-actually-immortal-88450872/ Immortality & Aging https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370421/ https://www.science.org.au/curious/earth-environment/animals-can-live-forever Lobster Cult https://www.urbo.com/content/your-new-god-worshiping-a-facebook-group-lobster/ https://www.ncbi.nlm.nih.gov/pmc/ar

Buckminster Fuller was a futurist and inventor with a silly name and a penchant for creating incredible inventions - from cars, to homes, to geodesic domes! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading References & Further Reading https://youtu.be/N1yxFDvqALI https://www.britannica.com/biography/R-Buckminster-Fuller https://www.bfi.org/about-fuller/big-ideas/dymaxion-world/dymaxion-map https://www.britannica.com/technology/geodesic-dome https://www.wired.com/2016/03/buckminster-fuller-brilliant-crank-lot-teach-silicon-valley/amp https://amp.theguardian.com/theguardian/2013/jul/04/buckminster-fuller-architecture-design https://library.stanford.edu/spc/manuscripts-divisi

Do you ever have a thought come to mind that doesn’t feel like something you’d think, a thought that can make you feel disgusted or uneasy? Those are intrusive thoughts, and while they’re strongly associated with mental illness, they might be a bit more common than you might think… You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading https://www.nhs.uk/mental-health/conditions/obsessive-compulsive-disorder-ocd/symptoms/ https://www.cam.ac.uk/research/news/scientists-identify-mechanism-that-helps-us-inhibit-unwanted-thoughts https://www.sciencedirect.com/science/article/abs/pii/S2211364913000675 https://www.livescience.com/amp/44687-most-people-have-unwanted-thoughts.html https://www.

American History tends to ignore the achievements of black people - which is why you probably haven’t heard of Benjamin Banneker… He was a polymath who went verbally toe to toe with Thomas Jefferson on the topic of slavery, was instrumental in the creation of the capital, and did so much more! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading https://www.whitehousehistory.org/benjamin-banneker https://archive.org/details/bulletinunitedst2311964unit/page/17/mode/1up?view=theater https://www.smithsonianmag.com/smart-news/three-things-know-about-astronomer-benjamin-bannekers-pioneering-career-180967136/ https://friendsofbenjaminbanneker.com/history/benjamin-banneker-2/ https://book

At the end of WWII hundreds of uranium cubes made for the Nazi nuclear program were taken by the USA, but they didn't take them all. Quite a number of these nuclear cubes went missing... A few have popped up here and there, until recently it's always been near impossible to tell if a cube is real, or just a really good replica - but scientists have just found a wild new way to find which ones are fakes... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading https://www.google.co.uk/amp/s/news.sky.com/story/amp/hundreds-of-cubes-of-nazi-uranium-are-missing-now-scientists-have-a-new-way-to-spot-them-12389326 https://www.washingtonpost.com/gdpr-consent/?next_url=https%3a%2f%2fwww.washin

Some men label themselves alphas - citing an old study on wolves, but surprisingly the results might not be as applicable to humans (or even wolves) as you might have thought… You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Wolf Packs https://animals.howstuffworks.com/mammals/wolf-pack-mentality.htm https://www.wolf.org/wp-content/uploads/2013/09/267alphastatus_english.pdf https://pubmed.ncbi.nlm.nih.gov/21963347 https://wolf.org/wolf-info/basic-wolf-info/wolf-faqs/#toggle-id-21 https://www.jstor.org/stable/3881436 Animal Social Behaviour & Hierarchies  https://www.bbc.com/worklife/article/20180925-with-females-in-charge-bonobo-society-is-more-chilled-out http://amydprice.co

Ever seen or heard something as you were half asleep and woken up to realise it wasn’t there? Hypnagogic and hypnopompic hallucinations are actually fairly common! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Hallucinations https://www.britannica.com/science/hallucination/Chemical-factors https://www.nhs.uk/mental-health/feelings-symptoms-behaviours/feelings-and-symptoms/hallucinations-hearing-voices/ Hypnagogic & Hypnopompic Hallucinations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988750/ https://www.researchgate.net/publication/14313158_Hypnagogic_and_Hypnopompic_Hallucinations_Pathological_Phenomena https://www.scielo.br/j/anp/a/C9cqbVby3nqWJrKYLvBngkk/?lang=en

Myers Briggs types are scientific evaluation of your personality… or at least that’s how they’re sold. Turns out that they might be barely more scientific than your horoscope. You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading What is MBTI? https://www.16personalities.com/free-personality-test https://www.mbtionline.com/en-US/Articles/2017/July/What-do-the-letters-in-the-Myers-Briggs-test-stand-for https://www.ncbi.nlm.nih.gov/books/NBK554596/ https://www.16personalities.com/country-profiles/global/world The Origins of MBTI https://www.youtube.com/watch?v=_NQqSnkI32A https://www.myersbriggs.org/my-mbti-personality-type/mbti-basics/isabel-briggs-myers.htm https://www.nature.com

Robots are becoming more and more human-like, but something weird happens when things become too human without quite making it all the way - we start to hate them… This is the uncanny valley, and you’ll find a lot of things in it. You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading https://www.aaai.org/Papers/AAAI/2005/RBC05-007.pdf https://onlinelibrary.wiley.com/doi/10.1111/medu.14184 https://spectrum.ieee.org/the-uncanny-valley https://www.karger.com/Article/Abstract/507812 https://www.jneurosci.org/content/39/33/6555 https://www.scientificamerican.com/article/why-uncanny-valley-human-look-alikes-put-us-on-edge/ https://www.cam.ac.uk/research/news/scientists-identify-possible-

Some children tell stories about lives they used to live… Are they just playing pretend or is this proof of reincarnation? Maybe science has some answers…  You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Past Lives, Jim Tucker & UVA’s Division of Perceptual Studies https://www.sciencedirect.com/science/article/pii/S1550830708000943 https://med.virginia.edu/perceptual-studies/our-research/children-who-report-memories-of-previous-lives/ https://med.virginia.edu/perceptual-studies/resources/advice-to-parents-of-children-who-are-spontaneously-recalling-past-life-memories/ https://www.vice.com/en/article/jgqygg/hard-science-of-reincarnation-past-lives https://www.npr.org/2014/01

Some people report being unable to stop daydreaming, to the point that it takes over their entire lives. Maladaptive Daydreaming isn’t yet a recognised disorder, but it only gets more strange from there... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Maladaptive Daydreaming in the Media https://www.bbc.co.uk/news/resources/idt-sh/the_daydream_that_never_stops https://digest.bps.org.uk/2018/06/25/people-with-maladaptive-daydreaming-spend-an-average-of-four-hours-a-day-lost-in-their-imagination/ https://www.theatlantic.com/health/archive/2015/04/when-daydreaming-replaces-real-life/391319/ https://www.nytimes.com/2021/04/10/at-home/daydreaming.html https://edition.cnn.com/2016/

Scientists went hunting for the Loch Ness Monster in 2019, but the search wasn’t all it seemed to be… You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Loch Ness Monster & The Myths https://www.livescience.com/61111-unusual-creature-sightings.html https://www.britannica.com/place/Loch-Ness-lake-Scotland-United-Kingdom https://www.lochnessproject.org/ Gimmell & His Survey https://www.livescience.com/loch-ness-monster-dna-study.html?_gl=1*e5q5rq*_ga*YW1wLVBxOEh1MnFUNHpkcG9VNHEzWmkyZWxoaURiOF9TYkc3ZUZ2QS1uVmNTSjFCZDduOFhRS0dQcXlQWkJsUzB3N1E. https://www.bbc.co.uk/news/uk-scotland-highlands-islands-49495145 https://www.theguardian.com/science/2019/sep/05/loch-ness-monste

Sophia the Robot is one of the most famous robots in the world, outside of those in Sci-fi. Although, there may be more fiction than fact when it comes to her artificial intelligence… You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading What is a Robot? https://www.britannica.com/technology/robot-technology Sophia The Robot https://www.youtube.com/watch?v=78-1MlkxyqI https://www.cnbc.com/2018/06/05/hanson-robotics-sophia-the-robot-pr-stunt-artificial-intelligence.html https://www.youtube.com/watch?v=7fnCQC7bLs0 https://www.hansonrobotics.com/sophia/ https://www.nationalgeographic.com/photography/article/sophia-robot-artificial-intelligence-science https://www.businessinsider.com/mee

This week we get sneezy and wheezy, because the plants are being sleazy. Hay Fever is one of the most common allergies in the world & there’s a lot of science behind it that might surprise you... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading Hay Fever https://www.nhs.uk/conditions/hay-fever/ https://www.britannica.com/science/hay-fever-pathology https://www.britannica.com/science/pollen https://www.britannica.com/plant/timothy https://www.britannica.com/science/rhinitis https://www.allergyuk.org/information-and-advice/statistics Antihistamines https://www.nhs.uk/conditions/antihistamines/#:~:text=How%20antihistamines%20work,which%20helps%20protect%20the%20body. https:/

NoahFinnce joins us this week to talk about PTSD, our patron-voted topic for this month! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon! http://patreon.com/sciguys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References & Further Reading 1. https://www.nhs.uk/mental-health/conditions/post-traumatic-stress-disorder-ptsd/overview/#:~:text=Post%2Dtraumatic%20stress%20disorder%20(PTSD)%20is%20an%20anxiety%20disorder,stressful%2C%20frightening%20or%20distressing%20events. 2. https://www.mind.org.uk/information-support/types-of-mental-health-problems/post-traumatic-stress-disorder-ptsd-and-complex-ptsd/symptoms/ 3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181836/ 4. https://www.nhs.uk/mental-health/conditions/post-traumatic-stress-disorder-ptsd/complex/ 5. https://www.mind.org.u