Neurology Minute

Dr. Jeff Lambe talks about progressive multiple sclerosis.  Show references: https://journals.lww.com/co-neurology/abstract/2025/06000/re_defining_progression_in_multiple_sclerosis.4.aspx  https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00281-8/abstract  https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(14)70256-X/abstract  https://www.tandfonline.com/doi/full/10.1080/14737175.2022.2143265  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0288967  https://jamanetwork.com/journals/jamaneurology/article-abstract/2809772  https://www.nejm.org/doi/full/10.1056/NEJMoa2415988   

Dr. Justin Abbatemarco discuss autoimmune encephalitis with a focus on outcomes.  Show reference:  https://www.neurology.org/doi/10.1212/WNL.0000000000210109  https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00463-5/abstract 

In part two of this two-part series, Dr. Dan Ackerman and Dr. Trey Bateman discuss handling patient requests for blood-based biomarkers for Alzheimer disease and interpreting test results.

Dr. Jessica Ailani and Dr. Kathleen Digre discuss the evolution of spontaneous intracranial hypotension (SIH) diagnosis and treatment over the past decade.

In part one of this two-part series, Dr. Dan Ackerman and Dr. Trey Bateman discuss current biomarkers for Alzheimer disease and how do you use them in clinic. 

Dr. Justin Abbatemarco discusses updates around MOGAD treatments.  Show references: https://jamanetwork.com/journals/jamaneurology/article-abstract/2822964  https://jnnp.bmj.com/content/95/11/1054 

Dr. Justin Abbatemarco discusses autoimmune encephalitis with a focus on outcomes. Show references: https://www.neurology.org/doi/10.1212/WNL.0000000000210109  https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00463-5/abstract 

Dr. Halley Alexander discusses the Neurology Today article, “The AAN Updates Its Position Statement on Seizures, Driver Licensure, and Medical Reporting,” by Gina Shaw, available in the latest issue of Neurology Today or at neurologytoday.com.  Show reference: The AAN Updates Its Position Statement on Seizures, Driver Licensure, and Medical Reporting

Dr. Greg Cooper and Dr. Joseph Therriault discuss the use of plasma biomarkers in diagnosing Alzheimer disease. Show reference: https://doi.org/10.1038/s43587-024-00731-y 

Dr. Halley Alexander and Dr. Paula Marques discuss sex differences in genetically determined epilepsies. Show reference:  https://www.neurology.org/doi/10.1212/NXG.0000000000200233 

Dr. Justin Abbatemarco discusses updates around treatments in AQP4+ NMOSD.  Show references: https://pubmed.ncbi.nlm.nih.gov/38760098/ https://www.neurology.org/doi/10.1212/NXI.0000000000200071  

In the final part of this three-part series, Dr. Justin Abbatemarco and Dr. Jiwon Oh discuss how to address questions related to BTK Inhibitors with patients. Show reference: https://www.nejm.org/doi/full/10.1056/NEJMoa2415985   https://www.nejm.org/doi/full/10.1056/NEJMoa2415988  

In part two of this three-part series, Dr. Justin Abbatemarco and Dr. Jiwon Oh discuss the clinical trial data available in both the relapsing and progressive cohorts. Show reference: https://www.nejm.org/doi/full/10.1056/NEJMoa2415985  https://www.nejm.org/doi/full/10.1056/NEJMoa2415988 

In part one of this three-part series, Dr. Justin Abbatemarco and Dr. Jiwon Oh discuss how Bruton Tyrosine Kinase (BTK) Inhibitors work and how they vary from other disease-modifying therapies.  Show reference: https://www.nejm.org/doi/full/10.1056/NEJMoa2415985  https://www.nejm.org/doi/full/10.1056/NEJMoa2415988 

Dr. Justin Abbatemarco provides an update on autologous hematopoietic stem cell transplantation in multiple sclerosis. Show reference: https://www.nature.com/articles/s41582-024-01050-x

In this women's history minute, Dr. Alison Christy discusses the life and legacy of Mary A. B. Brazier.

In part two of this two-part series, Dr. Jeff Ratliff and Dr. Harry Sutherland discuss the diverse strategies that residency programs implement to ensure residents can continue their education in a protected and supportive environment.  Show reference: https://www.neurology.org/doi/10.1212/NE9.0000000000200205 

In part one of this two-part series, Dr. Jeff Ratliff and Dr. Harry Sutherland discuss how neurology residency programs are incorporating didactic teaching methods to enhance learning outside the clinical environment. Show reference: https://www.neurology.org/doi/10.1212/NE9.0000000000200205 

Dr. Jessica Ailani and Dr. Richard B. Lipton discuss the significance of recognizing prodromal symptoms, the findings from the PRODROME trial, and the implications for clinical practice.  Show reference: https://www.neurology.org/doi/10.1212/CPJ.0000000000200359 

Dr. Tesha Monteith discusses an abstract that was presented at the AAN Annual Meeting titled, “Estrogen Exposure from Modern Hormonal Contraceptives and Vascular Risk in Women with Migraine: A Nationwide Electronic Health Record Database Study.” Show reference:  https://index.mirasmart.com/AAN2025/PDFfiles/AAN2025-002306.html