Science In Action

Researchers have developed a medical imaging technique which reveals where in the body HIV lies hidden, even when people have their infection well controlled by antiviral drugs. The team at the University of California, San Francisco hope this will lead to better treatments and even cures for HIV. As Timothy Henrich told us, they are also going to use the technique to investigate the notion that Long Covid is caused by the coronavirus persisting deep in the body's tissues.Also in the programme, Roland Pease reports from the vast particle accelerator in Switzerland where the famous Higgs particle was discovered ten years ago. The scientists there are preparing to begin experiments with an upgraded Large Hadron Collider to learn more about the particle and the fundamental nature of the Universe. Roland also talks to Frank Close, physicist and author of 'Elusive' - a new biography of Peter Higgs, a scientist as elusive as the particle named after him.Finally an international team of archaeologists have re

Should we worry about the most recent Omicron subvariants, BA 4 and BA5? They are the subtypes of the Covid-19 virus now dominant in southern Africa and spreading elsewhere. New research suggests that they are better at evading our antibody defences than other forms of the virus. Columbia University virologist David Ho explains the findings and what they means for us. Also, reducing air pollution makes agricultural crops grow better, how large wildfires warm the upper atmosphere, and the dolphins in the Red Sea which use secretions from corals and sponges as preventative medicines. Image Description: Coronavirus COVID-19 virus Credit: Getty ImagesPresenter: Roland Pease Producer: Andrew Luck-Baker

Science in Action this week comes from a vast gathering of earth scientists in Vienna, at the general assembly of the European Geosciences Union. Roland Pease hears the latest insights into the cataclysmic eruption of Hunga Tonga in the Pacific ocean from volcanologist Shane Cronin of the University of Auckland. He also talks to NASA's Michael Way about how the planet Venus might have acquired its hellish super-greenhouse atmosphere, and how the same thing could happen to planet Earth. There’s intriguing research from geologist John Tarduno of the University of Rochester that hints of a link between the ups and downs of the Earth’s magnetic field and the evolutionary history of animals. Fraser Lott of the UK's Hadley Centre explains his ideas for calculating an individual person's responsibility for climate change-driven extreme weather events.Image: Multi-beam sonar map of Hunga Tonga volcano post-eruption Credit: Shane Cronin/Uni of Auckland/Tonga Geological ServicesPresenter: Roland Pease Producer: Andr

Tree mortality in tropical moist forests in Australia has been increasing since the mid 1980s. The death rate of trees appears to have doubled over that time period. According to an international team of researchers, the primary cause is drier air in these forests, the consequence of human-induced climate change. According to ecologist David Bauman, a similar process is likely underway in tropical forests on other continents. Also in the programme: the outbreaks of monkeypox in Europe and North America… Could SARS-CoV-2 infection lingering in the gut be a cause of Long Covid? News of a vaccine against Epstein Barr virus, the cause of mononucleosis, various cancers and multiple sclerosis. Image: Credit: Getty ImagesPresenter: Roland Pease Producer: Andrew Luck-Baker

The heaviest thing in the Galaxy has now been imaged by the biggest telescope on Earth. This is Sagittarius A*, the supermassive black hole at the centre of our Galaxy – a gas and star-consuming object, a 4 million times the mass of the Sun. The Event Horizon Telescope is not one device but a consortium of radio telescopes ranging from the South Pole to the Arctic Circle. Their combined data allowed astronomers to focus in on this extreme object for the first time. Astronomer Ziri Younsi from University College London talks to Roland Pease about the orange doughnut image causing all the excitement.Also in the programme…Climatologist Chris Funk talks about the role of La Niña and climate change in the record-breaking two year drought that continues to threaten the lives and livelihoods of millions of people in East Africa.Was a pig virus to blame for the death of the first patient to receive a pig heart transplant? We talk to the surgeon and scientist at the University of Maryland School of Medicine who led

The Mekong Delta is home to 17 million people and is Vietnam’s most productive agricultural region. An international group of scientists warn this week that almost all of the low lying delta will have sunk beneath the sea within 80 years without international action. Its disappearance is the result of both sea level rise and developments such as dams and sand mining.Also in the programme: using the rumbling of traffic in Mexico City to monitor earthquake hazard, record-breaking quakes on Mars and a record-breaking high jumping robot.Photo: Mekong River in Kampong Cham, Cambodia Credit: Muaz Jaffar/EyeEm/Getty ImagesPresenter: Roland Pease Producer: Andrew Luck-Baker

Deadly heat has been building over the Indian sub-continent for weeks and this week reached crisis levels. India experienced its hottest March on record and temperatures over 40 degrees Celsius (and in some places approaching 50 degrees) are making it almost impossible for 1.4 billion people to work. It’s damaging crops and it’s just what climate scientists have been warning about. Roland Pease talks to Vimal Mishra of the Indian Institute of Technology in Gandhinagar about the impact and causes of the unprecedented heatwave.What could be behind the incidence of hepatitis in young children around the world in recent months? Ordinarily, liver disease in childhood is extremely rare. Could a virus normally associated with colds be responsible or is the Covid virus involved? Roland Pease talks to virologist William Irving of Nottingham University.Also in the programme: how climate change is increasing the likelihood of animal viruses jumping the species barrier to humans with global change modeller Colin Ca

As a series of UN climate reports have warned recently, drastic reductions in greenhouse gas emissions – a halving over the next decade – are needed if we are to keep global warming down to manageable levels. No sign of that happening. An emergency measure to buy time that’s sometimes discussed is solar geoengineering – creating an atmospheric sunscreen that reduces incoming solar heat. Sulphate compounds in volcanic gases or in industrial fumes attract water vapour to make a fine haze and have that effect. The difference would be starting a deliberate programme of injecting sulphate particles into the stratosphere. There are a host of arguments against it, including a revulsion against adding another pollutant to the atmosphere to offset the one, carbon dioxide, that’s giving us problems in the first place. Another objection, outlined this week, is that it could set back the global fight against malaria - a major killer in its own right. University of Cape Town ecologist Chris Trisos tells Roland Pease what

Brain scanning experiments reveal how psilocybin works to relieve severe depression. Psilocybin is the psychedelic substance in 'magic mushrooms'. The psychoactive chemical is currently in clinical trials in the UK and US as a potential treatment for depression and other mental illnesses. Professor David Nutt of Imperial College London tells Roland about the research Also in the show, worrying findings about the increase in premature deaths because of air pollution in growing cities in tropical Africa and Asia. An international group of climatologists has found that the tropical storms which struck Mozambique, Malawi and Madagascar in early 2022 had been made more intense by human-induced climate change. And astronomer David Jewitt used the Hubble telescope to measure the largest known comet in the solar system - it's huge at about 120 kilometres across.(Image: Mexican Psilocybe Cubensis. An adult mushroom raining spores. Credit: Getty Images)Presenter: Roland Pease Producer: Andrew Luck-Baker

Just over two months ago, the undersea volcano of Hunga Tonga erupted catastrophically, generating huge tsunamis and covering the islands of Tonga in ash. University of Auckland geologist Shane Cronin is now in Tonga, trying to piece together the sequence of violent events. Edinburgh University palaeontologist Ornella Bertrand tells us about her studies of the ancient mammals that inherited the Earth after the dinosaurs were wiped out. To her surprise, in the first 10 million years after the giant meteorite struck, natural selection favoured larger-bodied mammals, not smarter ones.At the University of Bristol, a team of engineers are developing skin for robots, designed to give future bots a fine sense of touch. Roland shakes hands with a prototype.A global satellite survey of the world’s largest coastal cities finds that most of them contain areas that are subsiding faster than the rate that the sea level is rising. Some cities are sinking more than ten times faster, putting many millions of people at

Russian forces in the forested exclusion zone around the Chernobyl nuclear site may be receiving potentially dangerous levels of radiation. After the nuclear accident trees were felled and radioactive material was buried across the site. As the forest regrew its took up much of that radiation - making it the most radioactive forest in the world according to Tom Scott from Bristol University who studies radiation levels in the region. The troop's activities, from digging trenches to lighting fires as missiles are fired, may be releasing radiation. Its unclear how dangerous this is, but those with the greatest and most immediate exposure risk are the troops themselves.Australia’s iconic Great Barrier Reef has suffered a mass bleaching event – where coral can be killed by rising temperatures. This is the latest in a series of such events which also affect other reefs. Kate Quigley from The Australian Institute of Marine Science is working to breed corals that can be more heat tolerant. However, she says this is

Unseasonably high temperatures have been recorded in both polar regions. Glaciologist Ruth Mottram discusses why they might be occurring now and the potential impact on her own work measuring climate change in Greenland.Erica Ollmann Saphire from the La Jolla Institute for Immunology tells us about her work developing new treatments for Ebola, she is looking to develop drugs which work not just on Ebola but also a range of related Viruses. And Eugene Koonin from the United States National Institutes of Health shows us how his computer modelling of the mutations of Sars Cov -2 suggest some good news - that the virus might not be able to mutate into further dangerous forms – at least not with its current set of genetic tools. Eugene is originally from Russia and both he and President Obama’s science advisor John Holdren are keen to keep up ties with scientists in Russia despite the international sanctions now being applied over the war in Ukraine. Both point out that many Russian scientists have opposed the w

Analysis of wastewater from sewage systems has provided an early warning system for the presence of Covid-19 in communities – showing up in the water samples before people test positive. It’s also possible to identify the variants and even specific genetic mutations. Davida Smyth of Texas A&M University has been using this technique in New York and found intriguing results - forms of the virus not present in humans. The suggestion is that mutated forms may be infecting other animals, possibly those present in the sewers. An analysis of long Covid, symptoms of fatigue, and ‘brain fog’ which occur long after initial infection, show that around a quarter of those infected develop these symptoms. Lucy Cheke of Cambridge University discusses the implications.The war in Ukraine has highlighted the importance of the region in supplying raw materials and energy to other countries, gas, cereal crops, and fertilisers in particular. As crop scientist John Hammond from Reading University explains, the stopping of fer

Hong Kong had been very successful at preventing the spread of Covid-19. Testing and isolation measures were very effective. However, vaccine uptake was low amongst elderly people and that says virologist Malik Peiris has now left them vulnerable to the highly infectious Omicron variant. The bombing of a scientific institute in the Ukrainian city of Kharkiv has echoes of the Stalinist purges says physicist and historical Mikhail Shifman. He tells us how the institute developed as a leading centre for physics in the 1930s, but scientists there fled or were murdered after being targeted by Stalin’s regime.Economic sanctions and other measures designed to isolate Russia are likely to have an impact on Russian participation in international scientific collaborations. Nikolay Voronin from the BBC’s Russian Service gives us his assessment of the immediate impact and, if the conflict continues long term, the potential for Russian science to retreat the kind of isolation last seen during the cold war.Presenter: Rolan

Wuhan's Huanan Seafood Market is associated with many of the first cases or Covid- 19, but data on precisely how and from where the virus might have first spread has been difficult to find. However a re-examination of the earliest samples collected from the market seem to pinpoint where the virus first showed itself. Sydney University virologist Eddie Holmes says this evidence will be crucial in determining which animals may have initially passed the virus to humans. Humans are known to have passed the Sars-Cov-2 virus to other animals, including cats, mink and deer. Canadian researchers have recorded the first incident of a modified form of the virus passing back from deer to humans. Virologist Samira Mubareka from the University of Toronto explains the implications. Chernobyl, the site of the worlds worst nuclear accident is back in the news as the Russian invasion of Ukraine led to a stirring up of nuclear material when troops entered the site. Ukraine has a number of nuclear reactors, Claire Corkhill, pr

A scheme in the US designed to prevent industrial espionage and the theft of intellectual property, is to be refocused after it was accused of unfairly targeting Chinese American scientists. We speak to Gang Chen, a professor from MIT who was falsely accused of financial crimes, and Holden Thorp Editor in Chief of the Journal Science who tells us why the ‘China Initiative’ is at odds with the reality of international scientific collaboration. And a huge study of farmed animals in China, from raccoon dogs to porcupines and Asian badgers, reveals that they carry a wide range of pathogens, including forms of avian flu and coronaviruses. Virologist Eddie Holmes from the University of Sydney, who was involved in the analysis, says these viruses may have the potential to jump species and infect humans – possibly leading to another pandemic.(Image: Students. Credit: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

Messenger RNA-based vaccines have been used successfully to kick start the antibody production needed to fight Covid-19. Now the technology has been successfully used to encourage the growth of new bones to heal severe fractures. The technique seems to work far better than the current alternatives says Maastricht University’s Elizabeth Rosado Balmayor.Ivory smuggling continues to be a lucrative business for international criminal gangs, however, DNA techniques to trace where ivory seized by law enforcement authorities originates are now so accurate that individual animals can be pinpointed to within a few hundred miles. This says Samuel Wasser at the University of Washington, can be used as evidence against those ivory trafficking gangs.And we look at development in attempts to detect and weigh neutrinos, elusive subatomic particles essential to our understanding of the makeup of the universe. Physicist Diana Parno from Carnegie Mellon University takes us through the latest findings.Philologists have borrowed

The Wuhan Institute of Virology has been at the centre of a controversy surrounding the origins of the virus which caused the Covid-19 pandemic. The work of the lab's previously obscure division looking at bat coronaviruses has been the subject of massive speculation and misinformation campaigns. Journalist and former biomedical scientist Jane Qiu has gained unique access to the lab. She has interviewed the staff there extensively and tells us what she found on her visits.And Tyler Starr from the Fred Hutchinson Institute in Seattle, has looked at a range of bat coronaviruses from around the world, looking to see whether they might have the capability to jump to humans in the future. He found many more than previously thought that either have or are potentially just a few mutations away from developing this ability.Nuclear fusion researchers at the 40-year-old Joint European Torus facility near Oxford in the UK for just the 3rd time in its long history, put fully-fledged nuclear fuel, a mixture of hydrogen is

We’re 40 years into the AIDS pandemic, and even with massive public health campaigns, still, 1 ½ million become infected with HIV each year; about half that number die of its ravages. And a study just out shows that this well-understood virus can still take on more worrying forms as a new variant has been uncovered. Although the total number of cases involved is small, and the new variant is as treatable as earlier strains, the finding underlines that viruses can become more infectious and more virulent. Back in October 2020, before we had effective vaccines, 36 plucky volunteers agreed to be deliberately infected with SARS-CoV-2 in order to better understand the infection process and outcomes in what’s known as a human “challenge” trial. Dr. Chris Chiu from Imperial College reveals what they’ve learned now the results of the study are in. We’ll hear about a new plastic that’s stronger than steel and as many gardeners have long suspected, – spring-flowering has over many years been occurring earlier and ear

There are now a number of biological indicators for the potential development of long covid. Immunologist Onur Boyman of Zurich University Hospital and Claire Steves, Clinical Senior Lecturer at King’s College London strives to tell us how pinpointing these factors is now helping in the development of strategies to predict the syndrome and prepare treatment.The James Webb telescope has reached its final orbit. The years of planning, preparation and rehearsal seem to have paid off. The telescope is now ready to begin its mission of looking back into the early universe. BBC Science correspondent Jonathan Amos has followed the mission.The widely held view that human development was propelled by our ancestors developing a taste for meat is being questioned by a new analysis of the fossil record. Paleoanthropologist Andrew Barr of George Washington University suggests part of the reason for this assumption is the sampling method, actively looking for evidence to support the hypothesis.And Michael Boudoin of Lil