Synopsis
The Neurology podcast is introduced by Editor-in-Chief Robert A. Gross, MD, PhD, who discusses several highlighted articles in the current issue of Neurology®. The podcast regularly features content from Neurology® Clinical Practice, Neurology® Genetics, and Neurology® Neuroimmunology & Neuroinflammation. Opening segments include interviews with authors who summarize a current article and discuss the main findings and clinical implications for neurologists. Regular features also include the Lesson of the Week, Delayed Recall, Whats Trending, and selected content from Neurology® Today. Podcast listeners can earn 0.5 AMA PRA Category 1 CME Credits by answering the multiple-choice questions related to Neurology content in the online Podcast Quiz. (Delayed Recall, Neurology® Clinical Practice, Neurology® Genetics, and Neurology® Neuroimmunology & Neuroinflammation contents are excluded from the CME program). The exams are posted weekly on Tuesday.
Episodes
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Stability and Accuracy of a Diagnosis of Parkinson Disease Over 10 Years
25/08/2025 Duration: 18minDr. Jeff Ratliff talks with Dr. Valtteri Kaasinen about the clinical challenges of diagnosing Parkinson disease and how that diagnosis can evolve over time. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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FDG-PET-Based Machine Learning Framework to Support Neurologic Decision-Making
21/08/2025 Duration: 13minDr. Trey Bateman talks with Dr. David T. Jones about how the StateViewer system leverages FDG-PET imaging and machine learning to improve diagnostic accuracy and clinical decision-making for Alzheimer disease and related disorders. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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Optimal Timing of Anticoagulation After Ischemic Stroke and Atrial Fibrillation
18/08/2025 Duration: 18minDr. Dan Ackerman talks with Dr. Urs Fischer about the optimal timing of anticoagulation after ischemic stroke in patients with atrial fibrillation. Read the related article in The Lancet. Disclosures can be found at Neurology.org.
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Implications for Diagnostic Criteria for Primary Lateral Sclerosis
14/08/2025 Duration: 22minDr. Jeff Ratliff talks with Drs. Michael A. Van Es and Eva de Boer about the current diagnostic criteria for PLS, the role of genetic testing, and the clinical implications for patient management. Read the related article in Neurology®. Read the additional related article mentioned in this episode. Disclosures can be found at Neurology.org.
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Long-Term Fatigue Following Transient Ischemic Attack
11/08/2025 Duration: 08minDr. BJ Hicks talks with Drs. Birgitte Hede Ebbesen and Boris Modrau about the study's methodology, findings, and implications for clinical practice, emphasizing the need for better awareness and support for TIA patients. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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Time Course and Severity of Cognitive Changes as a Function of Aβ Positivity and APOE Genotype in Alzheimer Disease
07/08/2025 Duration: 09minDr. Stacey Clardy talks with Casey R. Vanderlip about whether the accelerated decline in episodic memory among APOE4 carriers is due to increased Aβ deposition or heightened susceptibility to Aβ-related effects. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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The Effect of Epilepsy Surgery on Tonic–Clonic Seizures
04/08/2025 Duration: 19minDr. Halley Alexander talks with Dr. Juan Luis Alcala-Zermeno about the outcomes of epilepsy surgery, specifically for patients with tonic-clonic seizures. Read the related article in Epilepsia. Read the additional related article in Epilepsia. Listen to the previous podcast episode mentioned in this episode. Disclosures can be found at Neurology.org.
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August 2025 Recall: Topics on Dementia Diagnosis
01/08/2025 Duration: 01h43minThe August 2025 recall spotlights four previously released episodes on topics related to dementia diagnosis. The episode begins with Dr. Amy Brodtmann discussing the complexities of diagnosing frontotemporal dementia in clinical practice. Next, Dr. Joseph Therriault delves into the use of plasma biomarkers in diagnosing Alzheimer disease. In the third episode, Dr. Trey Bateman discusses the growing significance of blood-based biomarkers in Alzheimer disease. The episode concludes with Dr. Gregg Day discussing the clinical implications of using plasma biomarkers in real-world patient care. Podcast links: Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer Disease Using Plasma Biomarkers Understanding Blood-Based Biomarkers in Alzheimer Disease Diagnostic Performance of Plasma Biomarkers in the Outpatient Memory Clinic Article links: Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer’s Disease Using Plasma Biomarkers Adjusted to Cl
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Medical Student Perspectives on Stigma in FND
31/07/2025 Duration: 20minDr. Kathryn Krulisky talks with Dr. Jordan Garris about educational gaps in understanding FND, the impact of stigma on patient care, and the importance of empathy in medical training. Read the related article in Neurology® Education. Disclosures can be found at Neurology.org.
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A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis
28/07/2025 Duration: 15minDr. Shuvro Roy talks with Dr. Daniel Blockmans about the efficacy and safety of upadacitinib as a treatment option for giant-cell arteritis. Read the related article in The New England Journal of Medicine. Disclosures can be found at Neurology.org.
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Clinical Approach to Dementia Risk in Patients with Parkinson Disease
24/07/2025 Duration: 23minDr. Jason Crowell talks with Dr. Daniel Weintraub about clinical considerations and strategies for effective communication when addressing cognitive concerns in patients with Parkinson disease. Read the related article in Neurology®. Listen to the related podcast episode with Dr. Jeff Ratliff. Disclosures can be found at Neurology.org.
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Embolic Stroke of Undetermined Source Treated With Antiplatelet Agents or Anticoagulation
21/07/2025 Duration: 24minDr. Dan Ackerman talks with Dr. James Ernest Siegler about the complexities of treating ESUS and emphasizes the importance of personalized treatment approaches based on individual patient factors. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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Diagnostic Performance of Plasma Biomarkers in the Outpatient Memory Clinic
17/07/2025 Duration: 26minDr. Trey Bateman talks with Dr. Gregg Day about the study design, findings, and clinical implications of using plasma biomarkers in real-world patient care. Read the related article in Alzheimer's & Dementia. Disclosures can be found at Neurology.org.
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Efficacy of Aerobic Exercise and Coaching on Physical Fitness in Neuromuscular Disease
14/07/2025 Duration: 15minDr. Justin Abbatemarco talks with Dr. Eric L. Voorn about the efficacy of combined personalized home-based aerobic exercise and coaching on physical fitness in people with neuromuscular diseases, compared with usual care. Read the related article in Neurology®. Read the additional article that was referenced. Disclosures can be found at Neurology.org.
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hES Cell-Derived Dopaminergic Neurons for Parkinson Disease
10/07/2025 Duration: 31minDr. Jeff Ratliff talks with Dr. Claire Henchcliffe about the study's key findings while emphasizing the importance of educating patients about stem cell therapies and the ongoing advancements in this field. Read the related article in Nature. Disclosures can be found at Neurology.org.
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Insights from the AAN's Resident Survey
07/07/2025 Duration: 12minDr. Jason Crowell talks with Dr. Brian E. Emmert about the results from the 2022 AAN Resident Survey and explore areas for future improvement. Read the related article in Neurology® Education. Disclosures can be found at Neurology.org.
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July 2025 Recall: Practice of Neurology
02/07/2025 Duration: 01h10minThe July 2025 recall features four episodes on systems and innovation in delivering neurologic care. The episode begins with Dr. Scott Friedenberg discussing challenges faced by neurologists in balancing financial productivity with optimal patient care. The episode leads into a conversation with Dr. Marisa Patryce McGinley discussing the utilization of telemedicine in neurology, particularly focusing on disparities in access among different demographic groups. The conversation transitions to Dr. Lidia Moura talking about the implications of large language models for neurologic care. The episode concludes with Dr. Ashish D. Patel discussing headache referrals and the implementation of a design thinking approach to improve access to headache care. Podcast links: Empowering Health Care Providers Disparities in Utilization of Outpatient Telemedicine for Neurologic Care Large Language Models for Quality and Efficiency of Neurologic Care Using Design Thinking to Understand the Reason for Headache Referrals Artic
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Prehospital Large-Vessel Occlusion Stroke Detection Scales
30/06/2025 Duration: 16minDr. Dan Ackerman talks with Drs. Luuk Dekker and Jasper D. Daems about analyzing various anterior-circulation large-vessel occlusion (aLVO) stroke detection scales to determine which one is the most useful for prehospital triage. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
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2025 European Stroke Organization Conference Highlights
26/06/2025 Duration: 22minDr. Andy Southerland talks with Dr. Seemant Chaturvedi about several studies presented at the 2025 European Stroke Organization Conference (ESOC). Disclosures can be found at Neurology.org.
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Role of Central Sensitization Syndrome in Patients With Autonomic Symptoms
23/06/2025 Duration: 15minDr. Elizabeth Coon talks with Dr. Peter Novak about how central sensitization plays a role in the autonomic symptoms-sings dichotomy and the importance of addressing both conditions for optimal treatment. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurology.org.