Future Science Group

In this podcast, Mark Wrona (Principal Scientist at Waters Corporation; MA, USA) discusses his experience with HRMS and the current trends in the field of drug metabolism and pharmacokinetics (DMPK). He discusses the role HRMS plays in the analysis of biopharmaceuticals and compares the advantages of HRMS compared to triple quad.

Szabolcs Szarka (LGC) discusses the challenges, benefits and what the future may hold for HRMS in this podcast, exclusive to the Bioanalysis Zone Spotlight on HRMS in DMPK. You can find many more resources on HRMS via the HRMS in DMPK Spotlight pages on Bioanalysis Zone.

Hans Kierstead, CEO and founder of Aivita Biomedical, Speaks to Tristan Free, Digital Editor of BioTechniqes. Hans delves into his company's exciting new precision immunotherapy, currently undergoing phase II trials and discusses his 2018 run for US Congress, explaining why he is passionate about the need for scientists in politics.

In this podcast, senior scientists from Alturas Analytics (ID, USA), Katherine Yahvah, Chad Christianson and Michael Williams discuss some of the challenges they have faced and some of the solutions they have successfully implemented.

Joanne Hackett, Chief Commercial Officer at Genomics England, discusses their goals, completing major milestones in genomics research and approaching precision medicine.

Jade Parker, Senior Editor of Oncology Central is joined by Patrick Connor from AstraZeneca to discuss the Lung Ambition Alliance to find out how the Lung Ambition Alliance is looking to one day eliminate lung cancer as a cause of death and double the 5-year survival rate for the disease by 2025. Date of preparation: July 2019 Date of expiry: July 2020 Document ID: Z4-18671

In this interview, we talk to Mary Lame, Principal Applications Scientist who supports discovery bioanalysis for both large and small molecules, providing application development and support with Waters Corporation (Milford, MA, USA). Mary will discuss the key challenges scientists face developing robust peptide bioanalytical assays and introduces Waters approach for large molecule bioanalytical quantification method development including: pre-analytical sample preparation, as well as offering tips & tricks to help avoid the most common pitfalls working with peptides to help improve peptide assay performance and to streamline assay development. She also discusses how to enable highly sensitive and robust quantification of biomolecules from complex biomatrices.

Georgi Makin, Editor of 3DMedNet, is joined by Jacob Koffler (University of California San Diego; CA, USA) as they discuss how 3D printing is being used in spinal cord injury research. As part of 3DMedNet’s special feature - 3D in focus: applications in neuro R&D – Georgi and Jacob explore 3D printing in neurology and neuroscience. Find out more: Georgi Makin is the Editor of 3DMedNet (www.3dmednet.com), a community website that unites the diverse and multifaceted world of medical 3D printing with the aim of advancing the field, together. Jacob Koffler is a Bioengineer Neuroscientist working at the Center for Neural Repair within the School of Medicine at the University of California San Diego. Find out more about his work in the full interview on 3DMedNet: http://bit.ly/2LeBTLF Find out more about the neuro applications of 3D printing via 3DMedNet (http://bit.ly/2UhRRJc) and discover more about neurology, neuroscience and regenerative medicine via our supporting sister sites, Neuro Central (www.neuro-ce

BioTechniques Digital and Assistant Editors Abigail Sawyer and Tristan Free talk to Greg Mitchelotti of Metabolon about metabolomics, its potential applications in precision medicine and the new $4 million research collaboration with the Canadian Longitudinal Study of Aging and other Canadian institutions to identify biomarkers for frailty.

In this interview, hear from Catharina Brandsten, Head of Tissue Establishment and Kristina Runeberg, Site Head, at Takara Bio Europe, about deriving ethical and GMP-grade embryonic stem cells.

Hear more about the recent mass spectrometry product launches from SCIEX announced at ASMS 2019, including the new Acoustic Ejection Mass Spectrometry technology, in this interview with Neil Walsh (SCIEX; MA, USA).

Understanding automation in cell therapy manufacturing: an interview with Markus Gershater by Future Science Group

BioTechniques Digital and Assistant Editors Abigail Sawyer and Tristan Free talk to Theo Roth from the University of California San Francisco Marson Lab (CA, USA). Having recently made headlines for his work in T-cell engineering, Theo takes us through his groundbreaking CRISPR research, its potential impacts in CAR-T cell therapy and further afield, whilst also tackling the evolving ethics in gene editing and the potential benefits of using ssDNA over dsDNA for CRISPR techniques.

In this interview, David Harris (Charles River Laboratories; NC, USA) discusses the current global landscape for cell therapy, associated safety concerns and challenges, and preclinical animal models that are used to evaluate cellular therapies.

Discover more about the development of CAR-T cell therapies, their bioanalytical challenges and specialized antibody reagents that can be ustilized to overcome these in this interview with Michael Schwenkert (Bio-Rad Laboratories).

Abigail Sawyer and Tristan Free, from the BioTechniques digital team, speak to Head of Open Access Publishing at Future Science Group, Francesca Lake about antibodies: their advantages and flaws, pitfalls in their use and selecting the right antibodies for an experiment.

Eric Bonner (Eurofins) discusses the techniques he uses for assessing immunogenicity, key challenges and what the future may hold for the field in this podcast, exclusive to the Bioanalysis Zone Spotlight on immunogenicity. You can find many more resources on immunogenicity via the immunogenicity Spotlight pages on Bioanalysis Zone: http://bit.ly/2J6w15F

Georgi Makin, Editor of 3DMedNet, is joined by Jade Parker (Oncology Central) and Shana Cook (Milwaukee School of Engineering) as they discuss how patient experience with surgery can be improved with 3D printing, drawing from Shana’s personal experience 3D printing her own tumor from MRI data, following surgical resection of retroperitoneal leiomyosarcoma. Note: > At 5:11, Cook left Benedictine University in May of 2013, rather than March as quoted. > At 5:43, the MRI scan revealing the tumor was conducted in 2015, rather than 2013 as quoted. Find out more: Georgi Makin is the Editor of 3DMedNet (www.3dmednet.com), a community website that unites the diverse and multifaceted world of medical 3D printing with the aim of advancing the field, together. Jade Parker is the Senior Editor of Oncology Central (www.oncology-central.com), a free online platform that unites all aspects of oncology to support a multidisciplinary approach to progression of the field. Shana Cook is a Biomedical Engineering Student

Find out more about the role of exosomes in flow cytometry studies in this interview Joyce Slusser (KCAS; KS, USA).

Find out more about current challenges and recent developments in seen in the field of flow cytometry in this interview with Clara Brando and Ted Baginski (Eurofins; MO, USA).