Synopsis
Periodic audiocasts from Science Signaling, the signal transduction knowledge environment.
Episodes
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How countries could recover from coronavirus, lessons from an ancient drought, and feeling tactile waves in the hand
16/04/2020 Duration: 34minContributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about countries planning a comeback from a coronavirus crisis. What can they do once cases have slowed down to go back to some sort of normal without a second wave of infection? See all of our News coverage of the pandemic here. See all of our Research and Editorials here. As part of a drought special issue of Science, Contributing Correspondent Lizzie Wade joins Sarah to talk about water management and the downfall of the ancient Wari state. Sometimes called the first South American empire, the Wari culture successfully expanded throughout the Peruvian Andes 1400 years ago. Also this week, Yon Visell of the University of California, Santa Barbara, talks with Sarah about his Science Advances paper on the biomechanics of human hands. Our skin’s ability to propagate waves along the surface of the hand may help us sense the world around us. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the
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Does coronavirus spread through the air, and the biology of anorexia
09/04/2020 Duration: 25minOn this week’s show, Staff Writer Robert Service talks with host Sarah Crespi about a new National Academy of Sciences report that suggests the novel coronavirus can go airborne, the evidence for this idea, and what this means for the mask-wearing debate. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Staff Writer Jennifer Couzin-Frankel joins Sarah to talk about a burgeoning understanding of the biological roots of anorexia nervosa—an eating disorder that affects about 1% of people in the United States. From genetic links to brain scans, scientists are finding a lot more biology behind what was once thought of as a culturally driven disorder. This week’s episode was produced with help from Podigy. Episode page: https://www.sciencemag.org/podcast/does-coronavirus-spread-through-air-and-biology-anorexia Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).
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How COVID-19 disease models shape shutdowns, and detecting emotions in mice
02/04/2020 Duration: 31minOn this week’s show, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about modeling coronavirus spread and the role of forecasts in national lockdowns and other pandemic policies. They also talk about the launch of a global trial of promising treatments. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Nadine Gogolla, research group leader at the Max Planck Institute of Neurobiology, talks with Sarah about linking the facial expressions of mice to their emotional states using machine learning. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF) [Image: Damien Roué/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Kai Kupferschmidt
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Why some diseases come and go with the seasons, and how to develop smarter, safer chemicals
26/03/2020 Duration: 31minOn this week’s show, host Joel Goldberg gets an update on the coronavirus pandemic from Senior Correspondent Jon Cohen. In addition, Cohen gives a rundown of his latest feature, which highlights the relationship between diseases and changing seasons—and how this relationship relates to a potential coronavirus vaccine. Also this week, from a recording made at this year’s AAAS annual meeting in Seattle, host Meagan Cantwell speaks with Alexandra Maertens, director of the Green Toxicology initiative at Johns Hopkins University, Baltimore, about the importance of incorporating nonanimal testing methods to study the adverse effects of chemicals. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast ++ [Image: Let Ideas Compete/Flickr; Music: Jeffrey Cook] Authors: Joel Goldberg; Jon Cohen; Meagan Cantwell Listen to previous podcasts http://www.sciencemag.org/podcasts About the Science Podcast http://www.sciencemag.org/about/
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Ancient artifacts on the beaches of Northern Europe, and how we remember music
19/03/2020 Duration: 24minOn this week’s show, host Joel Goldberg talks with science journalist Andrew Curry about recent archaeological finds along the shores of Northern Europe. Curry outlines the rich history of the region that scientists, citizen scientists, and energy companies have helped dredge up. Also this week, from a recording made at this year’s AAAS annual meeting, host Meagan Cantwell speaks with Elizabeth Margulis, a professor at Princeton University, about musical memory. Margulis dives into several music cognition studies, as well as her own study on how Western and non-western audiences interpret the same song differently. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts About the Science Podcast [Image: Sebastian Reinecke/Flickr; Music: Jeffrey Cook] Authors: Meagan Cantwell, Joel Goldberg, Andrew Curry
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Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin
12/03/2020 Duration: 33minOn this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation i
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Dog noses detect heat, the world faces coronavirus, and scientists search for extraterrestrial life
05/03/2020 Duration: 33minOn this week’s show, Online News Editor David Grimm joins host Sarah Crespi to discuss how dogs’ cold noses may be able to sense warm bodies. Read the research. International News Editor Martin Enserink shares the latest from our reporters covering coronavirus. And finally, from a recording made at this year’s AAAS annual meeting, host Meagan Cantwell talks with Jill Tarter, chair emeritus at the SETI Institute, about the newest technologies being used to search for alien life, what a positive signal would look like, and how to inform the public if extraterrestrial life ever were detected. Episode page: https://www.sciencemag.org/podcast/dog-noses-detect-heat-world-faces-coronavirus-and-scientists-search-extraterrestrial-life This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).
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An ancient empire hiding in plain sight, and the billion-dollar cost of illegal fishing
27/02/2020 Duration: 47minThis week on the podcast, Contributing Correspondent Lizzie Wade joins host Sarah Crespi to discuss a turning point for one ancient Mesoamerican city: Tikal. On 16 January 378 C.E., the Maya city lost its leader and the replacement may have been a stranger. We know from writings that the new leader wore the garb of another culture—the Teotihuacan—who lived in a giant city 1000 kilometers away. But was this new ruler of a Maya city really from a separate culture? New techniques being used at the Tikal and Teotihuacan sites have revealed conflicting evidence as to whether Teotihuacan really held sway over a much larger region than previously estimated. Sarah also talks with Rashid Sumaila, professor and Canada research chair in interdisciplinary ocean and fisheries economics at the University of British Columbia, Vancouver’s Institute for the Oceans and Fisheries. You may have heard of illegal fishing being bad for the environment or bad for maintaining fisheries—but as Sumaila and colleagues report this we
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Brickmaking bacteria and solar cells that turn ‘waste’ heat into electricity
20/02/2020 Duration: 33minOn this week’s show, staff writer Robert F. Service talks with host Sarah Crespi about manipulating microbes to make them produce building materials like bricks—and walls that can take toxins out of the air. Sarah also talks with Paul Davids, principal member of the technical staff in applied photonics & microsystems at Sandia National Laboratories, about an innovation in converting waste heat to electricity that uses similar materials to solar cells but depends on quantum tunneling. And in a bonus segment, producer Meagan Cantwell talks with online news editor David Grimm on stage at the AAAS annual meeting in Seattle. They discuss how wildfires can harm your lungs, crime rates in so-called sanctuary states, and how factors such as your gender and country of origin influence how much trust you put in science. This week’s episode was edited by Podigy. Listen to previous podcasts About the Science Podcast Download a transcript (PDF)
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NIH’s new diversity hiring program, and the role of memory suppression in resilience to trauma
13/02/2020 Duration: 26minOn this week’s show, senior correspondent Jeffrey Mervis joins host Sarah Crespi to discuss a new National Institutes of Health (NIH) grant program that aims to encourage diversity at the level of university faculty with the long-range goal of increasing the diversity of NIH-grant recipients. Sarah also talks with Pierre Gagnepain, a cognitive neuroscientist at INSERM, the French biomedical research agency, about the role of memory suppression in post-traumatic stress disorder. Could people that are better at suppressing memories be more resilient to the aftermath of trauma? This week’s episode was edited by Podigy. Listen to previous podcasts About the Science Podcast Download a transcript (PDF)
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Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
06/02/2020 Duration: 27minOn this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research-link—CRISPR gene editing and immunotherapy for cancer—and tests it in patients. Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. Episode page This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).
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A cryo–electron microscope accessible to the masses, and tracing the genetics of schizophrenia
30/01/2020 Duration: 21minStructural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative. Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast
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Getting BPA out of food containers, and tracing minute chemical mixtures in the environment
23/01/2020 Duration: 26minAs part of a special issue on chemicals for tomorrow’s Earth, we’ve got two green chemistry stories. First, host Sarah Crespi talks with contributing correspondent Warren Cornwell about how a company came up with a replacement for the popular can lining material bisphenol A and then recruited knowledgeable critics to test its safety. Sarah is also joined by Beate Escher of the Helmholtz Centre for Environmental Research and the University of Tübingen to discuss ways to trace complex mixtures of humanmade chemicals in the environment. They talk about how new technologies can help detect these mixtures, understand their toxicity, and eventually connect their effects on the environment, wildlife, and people. Read more in the special issue on chemicals for tomorrow’s Earth. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF)
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Researchers flouting clinical reporting rules, and linking gut microbes to heart disease and diabetes
16/01/2020 Duration: 29minThough a U.S. law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement. Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes? This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: stu_spivack/Flickr; Music: Jeffrey Cook]
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Squeezing two people into an MRI machine, and deciding between what’s reasonable and what’s rational
09/01/2020 Duration: 21minGetting into a magnetic resonance imaging (MRI) machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to squeeze a whole other person into the same tube, while taking functional MRI (fMRI) measurements. Staff news writer Kelly Servick joins host Sarah Crespi to talk about the kinds of questions simultaneous fMRIs might answer. Also this week, Sarah talks with Igor Grossman, the director of the Wisdom and Culture Lab at the University of Waterloo, about his group’s Science Advances paper on public perceptions of the difference between something being rational and something being reasonable. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo Listen to previous podcasts About the Science Podcast [Image: Amanda/Flickr; Music: Jeffrey Cook] Authors: Kelly Servick, Sarah Crespi Transcript link: https://www.sciencemag.org/sites/default/files/SciencePodcast_200110.pdf
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Areas to watch in 2020, and how carnivorous plants evolved impressive traps
02/01/2020 Duration: 26minWe start our first episode of the new year looking at future trends in policy and research with host Joel Goldberg and several Science News writers. Jeffrey Mervis discusses upcoming policy changes, Kelly Servick gives a rundown of areas to watch in the life sciences, and Ann Gibbons talks about potential advances in ancient proteins and DNA. In research news, host Meagan Cantwell talks with Beatriz Pinto-Goncalves, a post-doctoral researcher at the John Innes Centre, about carnivorous plant traps. Through understanding the mechanisms that create these traps, Pinto-Goncalves and colleagues elucidate what this could mean for how they emerged in the evolutionary history of plants. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo Listen to previous podcasts About the Science Podcast [Image: Eleanor/Flickr] ++ Authors: Joel Goldberg, Jeffrey Mervis, Kelly Servick, Ann Gibbons, Meagan Cantwell
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Breakthrough of the Year, our favorite online news stories, and the year in books
19/12/2019 Duration: 42minAs the year comes to a close, we review the best science, the best stories, and the best books from 2019. Our end-of-the-year episode kicks off with Host Sarah Crespi and Online News Editor David Grimm talking about the top online stories on things like human self-domestication, the “wood wide web,” and more. News Editor Tim Appenzeller joins Sarah to discuss Science’s 2019 Breakthrough of the Year, some of the contenders for breakthrough, also known as runners-up, and the breakdowns—when science and politics just didn’t seem to mix this year. Finally, Science books editor Valerie Thompson brings her favorites from the world of science-inflected media. She and Sarah talk about some of the best books reviewed in Science this year, a food extinction book we should have reviewed, a pair of science-centric films, and even an award-winning birding board game. For more science books, films, and games, visit the books et al blog at blogs.sciencemag.org/books. This week’s episode was edited by Podigy.
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Hunting for new epilepsy drugs, and capturing lightning from space
13/12/2019 Duration: 29minAbout one-third of people with epilepsy are treatment resistant. Up until now, epilepsy treatments have focused on taming seizures rather than the source of the disease and for good reason—so many roads lead to epilepsy: traumatic brain injury, extreme fever and infection, and genetic disorders, to name a few. Staff Writer Jennifer Couzin-Frankel talks with host Sarah Crespi about researchers that are turning back the pages on epilepsy, trying to get to the beginning of the story where new treatments might work. And Sarah also talks with Torsten Neurbert at the Technical University of Denmark’s National Space Institute in Kongens Lyngby about capturing high-altitude “transient luminous events” from the International Space Station (ISS). These lightning-induced bursts of light, color, and occasionally gamma rays were first reported in the 1990s but had only been recorded from the ground or aircraft. With new measurements from the ISS come new insights into the anatomy of lightning. This week’s episode
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Debating lab monkey retirement, and visiting a near-Earth asteroid
05/12/2019 Duration: 31minAfter their life as research subjects, what happens to lab monkeys? Some are euthanized to complete the research, others switch to new research projects, and some retire from lab life. Should they retire in place—in the same lab under the care of the same custodians—or should they be sent to retirement home–like sanctuaries? Online News Editor David Grimm joins host Sarah Crespi to discuss recently penned legislation that pushes for monkey retirements and a new collaboration between universities and sanctuaries to create a retirement pipeline for these primates. Sarah also talks with Dante Lauretta, principal investigator for NASA’s Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REx) and a professor at the University of Arizona in Tucson, about the latest news from the asteroid Bennu. Within 1 week of beginning its orbit of the asteroid, OSIRIS-REx was able to send back surprising images of the asteroid ejecting material. It’s extremely rocky surface also took
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Double dipping in an NIH loan repayment program, and using undersea cables as seismic sensors
28/11/2019 Duration: 39minThe National Institutes of Health’s largest loan repayment program was conceived to help scientists pay off school debts without relying on industry funding. But a close examination of the program by investigative correspondent Charles Piller has revealed that many participants are taking money from the government to repay their loans, while at the same time taking payments from pharmaceutical companies. Piller joins Host Sarah Crespi to talk about the steps he took to uncover this double dipping and why ethicists say this a conflict of interest. Sarah also talks with Nate Lindsey, a Ph.D. candidate at the University of California, Berkeley, about turning a 50-meter undersea fiber optic cable designed to move data into a sensor for activity in the ocean and the land underneath. During a 4-day test in Monterey Bay, California, the cable detected earthquakes, faults, waves, and even ocean-going storms. For this month’s books segment, Kiki Sandford talks with Dan Hooper about his book At the Edge of Time: