New Books In Science

Genome sequencing is one of the most exciting scientific breakthroughs of the past thirty years. But what precisely does it involve and how is it developing? In Genomics: How Genome Sequencing Will Change Healthcare (Random House, 2022), Rachael Pells explains the science behind genomics. She analyses its practical applications in medical diagnosis and the treatment of conditions that range from cancer to severe allergic reactions to cystic fibrosis. She considers its potential to help with advances in agriculture and environmental science. She explores the ethics of genetic modification and the dangers involved when humans 'play God'. And she addresses the fundamental question: to what extent will future advances transform human longevity and the quality of life. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by beco

For many philosophers, the fact that scientists take different perspectives on the world is an obstacle to being a realist about the world. In Perspectival Realism (Oxford University Press, 2022), Michela Massimi argues that to the contrary the plurality of perspectives is the driving force behind realism. On her view, the scientific realism that emerges out of the perspectival nature of scientific representation takes perspectival models as inferential blueprints for exploring what is possible. The realist’s primitives are not essential properties, but the stable lawlike dependencies that are identified again and again from different perspectives. Massimi, who is professor of philosophy at the University of Edinburgh, also shows how scientific communities develop “natural kinds with a human face”: evolving groupings of modally robust phenomena that result from historically and culturally situated systems of scientific practices. Massimi’s book constructs a new vision of what scientific realism can be that wi

The last few years have brought to the fore the brilliant work of scientists as they worked to find a vaccine for Covid-19. But have you ever stopped to think about the role of biological materials in this and other science- and health-related research? In this episode of SSEAC Stories, Dr Natali Pearson is joined by Associate Professor Sonja van Wichelen to take a close look at the complex world of global health governance, with a particular focus on biotechnology and bioscience governance in Indonesia. They discuss the crucial role of biological materials exchange for scientific research, what rules govern their use, and the history of inequality that has underpinned scientific use of biological materials. Taking Indonesia’s recent efforts to gain leverage in the uneven space of the global bioeconomy, they explore how bioscience governance mechanisms can perpetuate, or sometimes help address, global power inequalities in the way biological material is used. About Sonja van Wichelen: Sonja van Wichelen is As

On July 4, 2012, the announcement came that one of the longest-running mysteries in physics had been solved: the Higgs boson, the missing piece in understanding why particles have mass, had finally been discovered. On the rostrum, surrounded by jostling physicists and media, was the particle's retiring namesake--the only person in history to have an existing single particle named for them. Why Peter Higgs? Drawing on years of conversations with Higgs and others, Close illuminates how an unprolific man became one of the world's most famous scientists. Close finds that scientific competition between people, institutions, and states played as much of a role in making Higgs famous as Higgs's work did. A revelatory study of both a scientist and his era, Elusive: How Peter Higgs Solved the Mystery of Mass (Basic Book, 2022) will remake our understanding of modern physics. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL

Imagine knowing years in advance whether you are likely to get cancer or having a personalized understanding of your individual genes, organs, and cells. Imagine being able to monitor your body's well-being, or have a diet tailored to your microbiome. The Secret Body reveals how these and other stunning breakthroughs and technologies are transforming our understanding of how the human body works, what it is capable of, how to protect it from disease, and how we might manipulate it in the future. Taking readers to the cutting edge of research, Daniel Davis shows how radical new possibilities are becoming realities thanks to the visionary efforts of scientists who are revealing the invisible and secret universe within each of us. Focusing on six important frontiers, Davis describes what we are learning about cells, the development of the fetus, the body's immune system, the brain, the microbiome, and the genome--areas of human biology that are usually understood in isolation. Bringing them together here for the

Today I talked to Michael Hannah about his book Extinctions: Living and Dying in the Margin of Error (Cambridge UP, 2021). Are we now entering a mass extinction event? What can mass extinctions in Earth's history tell us about the Anthropocene? What do mass extinction events look like and how does life on Earth recover from them? The fossil record reveals periods when biodiversity exploded, and short intervals when much of life was wiped out in mass extinction events. In comparison with these ancient events, today's biotic crisis hasn't (yet) reached the level of extinction to be called a mass extinction. But we are certainly in crisis, and current parallels with ancient mass extinction events are profound and deeply worrying. Humanity's actions are applying the same sorts of pressures - on similar scales - that in the past pushed the Earth system out of equilibrium and triggered mass extinction events. Analysis of the fossil record suggests that we still have some time to avert this disaster: but we must act

Taking over the world is a lot of work. Any supervillain is bound to have questions: What's the perfect location for a floating secret base? What zany heist will fund my wildly ambitious plans? How do I control the weather, destroy the internet, and never, ever die? Bestselling author and award-winning comics writer Ryan North has the answers. In How to Take Over the World: Practical Schemes and Scientific Solutions for the Aspiring Supervillain (Riverhead Books, 2022), he details a number of outlandish villainous schemes that harness the potential of today's most advanced technologies. Picking up where How to Invent Everything left off, his explanations are as fun and elucidating as they are completely absurd. You don't have to be a criminal mastermind to share a supervillain's interest in cutting-edge science and technology. This book doesn't just reveal how to take over the world--it also shows how you could save it. This sly guide to some of the greatest threats facing humanity accessibly explores emergin

In Different: Gender Through the Eyes of a Primatologist (W. W. Norton, 2022), world-renowned primatologist Frans de Waal draws on decades of observation and studies of both human and animal behavior to argue that despite the linkage between gender and biological sex, biology does not automatically support the traditional gender roles in human societies. While humans and other primates do share some behavioral differences, biology offers no justification for existing gender inequalities. Using chimpanzees and bonobos to illustrate this point--two ape relatives that are genetically equally close to humans--de Waal challenges widely held beliefs about masculinity and femininity, and common assumptions about authority, leadership, cooperation, competition, filial bonds, and sexual behavior. Chimpanzees are male-dominated and violent, while bonobos are female-dominated and peaceful. In both species, political power needs to be distinguished from physical dominance. Power is not limited to the males, and both sexe

Inequality is an urgent global concern, with pundits, politicians, academics, and best-selling books all taking up its causes and consequences. In Inequality: A Genetic History (MIT Press, 2022), Carles Lalueza-Fox offers an entirely new perspective on the subject, examining the genetic marks left by inequality on humans throughout history. Lalueza-Fox describes genetic studies, made possible by novel DNA sequencing technologies, that reveal layers of inequality in past societies, manifested in patterns of migration, social structures, and funerary practices. Through their DNA, ancient skeletons have much to tell us, yielding anonymous stories of inequality, bias, and suffering. Lalueza-Fox, a leader in paleogenomics, offers the deep history of inequality. He explores the ancestral shifts associated with migration and describes the gender bias unearthed in these migrations--the brutal sexual asymmetries, for example, between male European explorers and the women of Latin America that are revealed by DNA analy

There are three major myths of human nature: humans are divided into biological races; humans are naturally aggressive; and men and women are wholly different in behavior, desires, and wiring. Race, Monogamy, and Other Lies They Told You: Busting Myths about Human Nature (Second Edition) (U California Press, 2022) counters these pervasive and pernicious myths about human behavior. Agustín Fuentes tackles misconceptions about what race, aggression, and sex really mean for humans, and incorporates an accessible understanding of culture, genetics, and evolution that requires us to dispose of notions of "nature or nurture." Presenting scientific evidence from diverse fields, including anthropology, biology, and psychology, Fuentes devises a myth-busting toolkit to dismantle persistent fallacies about the validity of biological races, the innateness of aggression and violence, and the nature of monogamy, sex, and gender. This revised and expanded edition provides up-to-date references, data, and analyses, and addr

Niels Bohr was a central figure in quantum physics, well known for his work on atomic structure and his contributions to the Copenhagen interpretation of quantum mechanics. In From Data to Quanta: Niels Bohr’s Vision of Physics (U Chicago Press, 2021), philosopher of science Slobodan Perović explores the way Bohr practiced and understood physics, and analyzes its implications for our understanding of modern science. Perović develops a novel approach to Bohr’s understanding of physics and his method of inquiry, presenting an exploratory symbiosis of historical and philosophical analysis that uncovers the key aspects of Bohr’s philosophical vision of physics within a given historical context. Ana Georgescu studied astrophysics and physics at Harvard University and is now a science consultant and writer based in New York City. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Plan S: the open access initiative that changed the face of global research.  Robert-Jan Smits and Rachael Pells's book Plan S for Shock: Science. Shock. Solution. Speed. (Ubiquity Press, 2022) tells the story of open access publishing - why it matters now, and for the future. In a world where information has never been so accessible, and answers are available at the touch of a fingertip, we are hungrier for the facts than ever before - something the Covid-19 crisis has brought to light. And yet, paywalls put in place by multi-billion dollar publishing houses are still preventing millions from accessing quality, scientific knowledge - and public trust in science is under threat. On 4 September 2018, a bold new initiative known as 'Plan S' was unveiled, kickstarting a world-wide shift in attitudes towards open access research. For the first time, funding agencies across continents joined forces to impose new rules on the publication of research, with the aim of one day making all research free and available to

Insects are seldom mentioned in discussions surrounding human history, yet they have dramatically impacted today's societies. The Silken Thread: Five Insects and Their Impacts on Human History (Oxford UP, 2021) places them front and center, offering a multidisciplinary view of their significance. Diseases vectored by insects have killed more people than all weapons of war. Fleas are common pests, but some can transmit illnesses such as the bubonic plague. In fact, three pandemics can be traced back to them. Epidemics of typhus have been caused by lice. Conversely, humans have also benefitted from insects for millennia. Silk comes from silkworms and honey comes from bees. Despite the undeniably powerful effects of insects on humans, their stories are typically left out of our history books. In The Silken Thread, entomologists Robert. N. Wiedenmann and J. Ray Fisher link the history of insects to the history of empires, cultural exchanges, and warfare. The book narrows its focus to just five insects: a moth, a

Coral reefs are a microcosm of our planet: extraordinarily diverse, deeply interconnected, and full of wonders. When they're thriving, these fairy gardens hidden beneath the ocean's surface burst with color and life. They sustain bountiful ecosystems and protect vulnerable coasts. Corals themselves are evolutionary marvels that build elaborate limestone formations from their collective skeletons, broker symbiotic relationships with algae, and manufacture their own fluorescent sunblock. But corals across the planet are in the middle of an unprecedented die-off, beset by warming oceans, pollution, damage by humans, and a devastating pandemic. Juli Berwald fell in love with coral reefs as a marine biology student, entranced by their beauty and complexity. Alarmed by their peril, she traveled the world to discover how to prevent their loss. She met scientists and activists operating in emergency mode, doing everything they can think of to prevent coral reefs from disappearing forever. She was so amazed by the ing

Debates about science and religion are rarely out of the news. Whether it concerns what's being taught in schools, clashes between religious values and medical recommendations, or questions about how to address our changing global environment, emotions often run high and answers seem intractable. Yet there is much more to science and religion than the clash of extremes.  As Thomas Dixon and Adam Shapiro show in Science and Religion: A Very Short Introduction (Oxford UP, 2022), a whole range of views, subtle arguments, and fascinating perspectives can be found on this complex and centuries-old subject. They explore the key philosophical questions that underlie the debate, but also highlight the social, political, and ethical contexts that have made the tensions between science and religion such a fraught and interesting topic in the modern world. In this new edition, Dixon and Shapiro connect historical concepts such as evolution, the heliocentric solar system, and the problem of evil to present-day issues in

Today I talked to astronomer Charlotte Christensen of Grinnell College. She studies (among other things) dwarf galaxies.  Dwarf galaxies, galaxies with masses about 10% that of the Milky Way or smaller, such as the Magellanic Clouds, are perfect laboratories for studying galaxy evolution. The small gravitational potentials of dwarf galaxies make them uniquely sensitive environments for understanding the physics of galaxy formation, including the processes that drive gas accretion, gas loss, and star formation. Dwarf satellites of the Milky Way or similar nearby galaxies may help constrain these processes, but only if the effect of the large halo environment the dwarf galaxies exist in can be well understood.  Marshall Poe is the founder and editor of the New Books Network. He can be reached at marshallpoe@newbooksnetwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Hidden from view, microfluidics underlies a variety of devices that are essential to our lives, from inkjet printers to glucometers for the monitoring of diabetes. Microfluidics--which refers to the technology of miniature fluidic devices and the study of fluids at submillimeter levels--is invisible to most of us because it is hidden beneath ingenious user interfaces. In this book, Albert Folch, a leading researcher in microfluidics, describes the development and use of key microfluidic devices. He explains not only the technology but also the efforts, teams, places, and circumstances that enabled these inventions. Folch reports, for example, that the inkjet printer was one of the first microfluidic devices invented, and traces its roots back to nineteenth-century discoveries in the behavior of fluid jets. He also describes how rapid speed microfluidic DNA sequencers have enabled the sequencing of animal, plant, and microbial species genomes; organs on chips facilitate direct tests of drugs on human tissue, l

As a trainee doctor, A. J. Lees was enthralled by his mentors: esteemed neurologists who combined the precision of mathematicians, the scrupulosity of entomologists, and the solemnity of undertakers in their diagnoses and treatments. For them, there was no such thing as an unexplained symptom or psychosomatic problem--no difficult cases, just interesting ones--and it was only a matter of time before all disorders of the brain would be understood in terms of anatomical, electrical, and chemical connections. Today, this kind of "holistic neurology" is on the brink of extinction as a slavish adherence to protocols and algorithms--plus a worship of machines--runs the risk of destroying the key foundational clinical skills of listening, observation, and imagination that have been at the heart of the discipline for more than 150 years. In Brainspotting: Adventures in Neurology (Notting Hill Editions, 2022), Lees takes us on a kind of Sherlock Holmes tour of neurology, giving the reader insight into--and a defense o

Madagascar is a place of change. A biodiversity hotspot and the fourth largest island on the planet, it has been home to a spectacular parade of animals, from giant flightless birds and giant tortoises on the ground to agile lemurs leaping through the treetops. Some species live on; many have vanished in the distant or recent past. Over vast stretches of time, Madagascar's forests have expanded and contracted in response to shifting climates, and the hand of people is clear in changes during the last thousand years or so. Today, Madagascar is a microcosm of global trends. What happens there in the decades ahead can, perhaps, suggest ways to help turn the tide on the environmental crisis now sweeping the world. Sloth Lemur's Song: Madagascar from the Deep Past to the Uncertain Present (U Chicago Press, 2022) is a far-reaching account of Madagascar's past and present, led by an expert guide who has immersed herself in research and conservation activities with village communities on the island for nearly fifty y

The puzzling lack of evidence for the peculiar but widespread belief that birds have no sense of smell irked evolutionary biologist Danielle Whittaker. Exploring the science behind the myth led her on an unexpected quest investigating mysteries from how juncos win a fight to why cowbirds smell like cookies. In The Secret Perfume of Birds: Uncovering the Science of Avian Scent (Johns Hopkins UP, 2022)--part science, part intellectual history, and part memoir--Whittaker blends humor, clear writing, and a compelling narrative to describe how scent is important not just for birds but for all animals, including humans. Whittaker engagingly describes how emerging research has uncovered birds' ability to produce complex chemical signals that influence their behavior, including where they build nests, when they pick a fight, and why they fly away. Mate choice, or sexual selection--a still enigmatic aspect of many animals' lives--appears to be particularly influenced by smell. Whittaker's pioneering studies suggest th