Synopsis
Every Friday at 3:00ET / 12PT, CXOTalk brings together top business leaders to discuss leadership, innovation, and disruption. Go to http://cxotalk.com to participate LIVE.
Episodes
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AI Inequality EXPOSED: When Algorithms Fail | CXOTalk #882
09/06/2025 Duration: 56minIn episode 882 of CXOTalk, Michael Krigsman sits down with Kevin De Liban, founder of TechTonic Justice and former legal aid attorney, who reveals the shocking truth about AI's impact on vulnerable communities. De Liban shares how 92 million low-income Americans now have critical life decisions, such as healthcare, housing, employment, and government benefits, that are determined by algorithms that often fail catastrophically.Drawing from his groundbreaking 2016 legal victory in Arkansas, where he successfully challenged an algorithm that devastated the lives of disabled Medicaid recipients, De Liban exposes the myth of AI neutrality and demonstrates how these systems reflect the biases and incentives of their creators. He explains why self-regulation and "ethical AI" initiatives often fail when they conflict with business interests, and why effective regulation is crucial.What you'll learn: The real scale of AI harm affecting 92 million Americans Why AI systems aren't neutral decision-m
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Are You Making These COMMON AI Organization Mistakes? | CXOTalk #881
26/05/2025 Duration: 53minHow do you transform a tech giant into an AI-first (or AI-native) organization? In CXOTalk episode 881, Cisco's President and Chief Product Officer, Jeetu Patel, reveals the blueprint for building AI-native companies in 2025.Discover why AI won't replace your job – but someone using AI better than you will. Learn how Cisco is revolutionizing its entire operation, from engineering to customer support, with artificial intelligence at the core.Key topics covered:Building an AI-first culture and overcoming employee resistanceManaging non-deterministic AI systems and security challengesThe global AI race and why speed matters more than perfectionAutonomous agents and the future of workEthical AI implementation across international bordersReal-world AI applications transforming enterprise operationsPatel shares candid insights about jailbreaking AI models, the importance of "market-in" thinking, and why he spends 2-3 hours nightly learning with AI. Plus, hear his perspective on global AI partnerships and why regula
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What Big Changes Are Coming to AI in 2025? | CXOTalk #880
21/05/2025 Duration: 53minAI strategist and TikTok commentator Nate B. Jones joins CXOTalk host Michael Krigsman to explain the high-stakes race among OpenAI, Google, Meta, and others to advance large language models. The discussion explores token economics, model specialization, and hands-on prompting skills every executive needs to translate AI progress into business results. Watch Episode 880 now and subscribe for weekly conversations with top tech leaders.
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Will AI Change Customer Service Forever in 2025? | CXOTalk #879
08/05/2025 Duration: 22minJoin GoTo and CXOTalk for a deep dive into the world of AI and the virtual workforce. Learn about AI receptionists, agentic AI, and how AI agents dramatically improve customer service for small and mid-sized companies.Our guest is Damon Covey, General Manager of UCC at GoTo.Learn more at: www.goto.com
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AI Agents for Small Business: What You Need to Know | CXOTalk #878
06/05/2025 Duration: 23minJoin Andrew Wesbecher (Powered_By) and Michael Krigsman on CXOTalk episode 878 to discuss how AI agents can help small businesses succeed in 2025. Learn from industry experts and discover the benefits of using AI technology for your SMB to stay ahead of the competition!Learn more from www.poweredby.agency===================
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What If AI Could SPEED UP Clinical Trials by 90%? | CXOTalk #877
01/05/2025 Duration: 53minLearn about the impact of AI in healthcare in CXOTalk episode 877 on AI in clinical trials. Discover how artificial intelligence is revolutionizing clinical trials and the potential benefits for the healthcare industry.AI promises faster, safer clinical trials and better patient experiences. Clario's EVP & Chief Information Technology & Product Officer, Jay Ferro, joins CXOTalk host Michael Krigsman to explain how his team unifies IT, product, data, security, and marketing under one roof, giving sponsors, sites, and patients a single, seamless platform. He outlines responsible AI governance with legal, medical, privacy, and security leaders. He shows how predictive tools speed recruitment, sharpen protocol design, cut dropout risk, and support image interpretation while physicians keep the final judgment.Watch to learn• How a unified tech-product structure cuts cost and removes friction• Steps for enterprise-wide AI oversight in a regulated environment• Real use cases for AI in recruitment, imagin
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Will AI Agents Replace Your Entire Workforce in 2025? | CXOTalk #876
17/04/2025 Duration: 52minJoin this deep dive into Agentic AI with Phil Fersht of HFS Research on CXOTalk episode #876. Learn about the future of AI and how it impacts business strategies.
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AI Regulation & Innovation: Insights from the UK House of Lords | CXOTalk #875
07/04/2025 Duration: 57minHow do top policymakers balance fostering technological advancement with necessary oversight? Join Michael Krigsman as he speaks with Lord Chris Holmes and Lord Tim Clement-Jones, members of the UK House of Lords, for a deep dive into the critical intersection of technology policy, innovation, and public trust.In this conversation, explore:-- The drive for "right-sized" AI regulation that supports innovators, businesses, and citizens.-- Strategies for effective AI governance principles: transparency, accountability, and interoperability.-- The importance of international collaboration and standards in a global tech ecosystem.-- Protecting intellectual property and creators' rights in the age of AI training data.-- Managing the risks associated with automated decision-making in both public and private sectors.-- The push for legal clarity around digital assets, tokenization, and open finance initiatives.-- Building and maintaining public trust as new technologies become more integrated into socie
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AI in Healthcare: Reality, ROI, and Patient Outcomes | CXOTalk #874
03/04/2025 Duration: 54minWhat's genuinely working with AI in healthcare? Join Michael Krigsman with experts Dr. David Bray (Stimson Center), Teresa Carlson (General Catalyst Institute), and Dr. David Reich (Mount Sinai Health System) as they cut through the hype.Discover practical insights on:-- Integrating AI into clinical workflows-- Calculating the real ROI of AI investments-- Overcoming data interoperability challenges-- The impact of policy and regulation-- Shifting towards value-based care with AILearn how artificial intelligence impacts decisions, data, and the future of patient care.
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Mastering 5G Network Security (AI, Zero Trust, and SASE) with Palo Alto Networks | CXOTalk #873
18/03/2025 Duration: 21minIn episode 873, we dive deep into 5G security with Anand Oswald, Sr. VP and GM of Network Security at Palo Alto Networks. Explore the transformative impact of 5G on industries and how the convergence of technologies like AI and IoT drives 5G digital transformations. Learn about managing sophisticated threats, the importance of a zero-trust approach, and the difference between public and private 5G network security. Discover real-world examples of 5G technologies in action and get key advice for securing your enterprise-grade 5G infrastructure from the ground up.
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Ex Apple Engineers: The AI Future of Photography | CXOTalk #872
17/03/2025 Duration: 59minIn episode 872 of CXOTalk, we explore the capabilities of AI-powered smartphones in professional photography. Joining us are two former Apple engineers, Ziv Atar and Tom Bishop. They are the minds behind the iconic portrait mode on iPhones and are now the founders of GLASS Imaging. They discuss how neural networks are revolutionizing smartphone cameras, aiming to drive hardware changes resulting in smaller, cheaper, and higher-quality cameras. The discussion covers computational photography, the evolution and potential of AI in image processing, and whether smartphones can match or surpass traditional cameras. The episode includes insightful comparisons and examples demonstrating AI's incredible improvements to digital photography.
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Building an AI Startup: What's Different in 2025? | #871
06/03/2025 Duration: 57minDiscover the future of AI startups and enterprise adoption with Arvind Jain, Founder and CEO of Glean, in CXOTalk episode 871. Arvind explains:How AI startups differ from traditional software companiesStrategies for rapid revenue scaling in AI-native businessesKey considerations for CIOs evaluating AI solutionsManaging AI ethics, security, and transparency risksPractical advice for entrepreneurs starting AI venturesThe evolving landscape of AI integration in enterprise workflowsLearn why centralizing AI strategy, focusing on small wins, and prioritizing security are crucial for successful AI implementation. Arvind emphasizes the importance of solving real business problems and adapting to the rapidly changing AI landscape.Whether you're a CIO, entrepreneur, or business leader interested in AI's transformative potential, this episode offers actionable insights to guide your AI journey.
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Telecom industry: Disruption, transformation, and customer experience with AT&T | #870
26/02/2025 Duration: 52minIn CXOTalk episode 870, we present an exclusive interview with Jenifer Robertson, the Executive Vice President of Mass Markets at AT&T. With oversight of $100 billion in revenue and 60,000 employees, Jenifer recounts her journey from systems analytics and coding to her current leadership position. The discussion emphasizes AT&T's customer-centric strategies, advancements in AI, and the company's response to disruptions in telecom. Jenifer also discusses the significance of convergence between fiber and wireless technologies, the customer demands shaping the telecom industry, and how to balance technological innovation with customer needs. Additionally, the episode offers insights into female leadership in technology and the philosophy of 'humble confidence' in leadership roles.
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Building trust in AI: A CIO's perspective | CXOTalk #869
18/02/2025 Duration: 56minJoin Michael Krigsman on CXOTalk as leading CIO advisors Tim Crawford and Isaac Sacolick unpack actionable strategies for Chief Information Officers to thrive in the AI era. This episode dives into critical challenges and opportunities, offering insights on:Governance & Data Strategy: Prioritize robust AI governance frameworks and invest in clean, scalable data to drive reliable innovation. Sacolick stresses early integration of compliance and ethics, while Crawford underscores the need for a holistic data strategy to avoid “garbage in, garbage out” pitfalls.Change Management: Proactively educate teams and collaborate with HR (CHRO) to secure training budgets, empowering employees to adapt as AI reshapes workflows in IT, sales, and customer support.Innovation vs. Efficiency: Focus on AI initiatives that transform business models and customer experiences—not just productivity gains. Align pilots with clear OKRs, balancing agility with measurable outcomes to escape “pilot purgatory.”Collaboration & Risk
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An Advanced Look at AI Agents, Part 2 | #868
12/02/2025 Duration: 53minIn CXOTalk Episode 868, host Michael Krigsman interviews Praveen Akkiraju, Managing Director at Insight Partners, to explore the world of agentic AI.Praveen explains AI agents, their reliance on large language models (LLMs), and how they differ from traditional applications. He discusses AI agents' current state and reliability, explains the layered architecture involving user interfaces, reasoning, and dynamic querying, and highlights the importance of evaluation loops and human-in-the-loop systems for consistent output.The episode also discusses practical use cases in various sectors like coding, customer support, and IT operations. It explores the complex economics, security considerations, and future trajectory of AI agents in both startups and large enterprises.
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AI Snake Oil: Princeton Professor Exposes AI Truths | #867
28/01/2025 Duration: 57minIn CXOTalk episode 867, Princeton professor Arvind Narayanan, co-author of AI Snake Oil, reveals why many AI products fail to deliver on their promises and how leaders can distinguish hype-driven solutions from those that create value. Exploring the landscape of AI advancements, deceptions, and limitations, Narayanan explains how to detect genuine AI innovations from overhyped and potentially harmful applications. We discuss real-world examples, ethical concerns, and the role of policy and regulation in mitigating AI snake oil. Tune in to learn actionable insights for consumers and businesses and explore how AI reshapes industries while posing unique challenges and opportunities. #enterpriseai #cxotalk #aihype #aiethics
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Enterprise AI: A Board of Directors Perspective | CXOTalk #866
17/01/2025 Duration: 56minHow are boards of directors navigating the complex world of enterprise AI and AI adoption? Join Michael Krigsman in conversation with independent board member Adriana Karaboutis (former technology leader at Dell, Biogen, National Grid) as they dissect the current state of AI adoption across industries. Discover the key drivers and roadblocks, the tension between innovation and risk, and what to do when board members lack tech understanding. This is a must-watch for CEOs, CIOs, and anyone who shapes their organization's AI strategy.
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AI Ethics and Trustworthy AI: Navigating Truth and Deception | #864
27/12/2024 Duration: 57minArtificial intelligence is reshaping the world, but how can we trust it and build ethical AI? In this episode of CXOTalk, we explore the dual nature of AI—its potential to build trust and its risks of enabling deception. Join host Michael Krigsman and our expert guests:
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Securing Critical Infrastructure: Precision AI for OT Environments | #865
17/12/2024 Duration: 16minHow can AI protect critical infrastructure from cyberattacks? Discover practical solutions for securing operational technology (OT) and IT systems in this insightful conversation with Anand Oswal, SVP and GM of Network Security at Palo Alto Networks. Learn why over 70% of industrial organizations faced cyber-attacks last year and how precision AI is revolutionizing OT security. Oswal reveals strategies for: • Protecting legacy industrial systems • Managing remote access securely • Implementing zero trust in OT environments • Using AI-driven threat detection • Meeting new compliance requirements Essential viewing for technology leaders responsible for securing manufacturing facilities, utilities, oil & gas operations, and other critical infrastructure. Learn how AI-powered security solutions can protect your operations while enabling digital transformation. CXOTalk Website: www.cxotalk.com Subscribe to Our Newsletter: www.cxotalk.com/subscribe Read the full transcript and episode summary: www.cxota
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AI Ethics, Governance, Responsible AI: Views from the CIA's Deputy Privacy Officer | CXOTalk #863
16/12/2024 Duration: 53minAre you navigating the complex landscape of AI ethics and governance?