American Journal Of Psychiatry Audio

This audio program discusses public perceptions of mental illness, research on the neural circuitry of postpartum depression, the genetics of autism, and psychotherapy for older adults with major depression and executive dysfunction. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses delirium in infants in critical care settings; a study of suicidal women with borderline personality disorder comparing subgroups with and without PTSD; subthreshold hypomania in major depressive disorder patients; effect of hypertension and body mass index on cognition in schizophrenia; and the relationship of antidepressant step therapy to overall medical utilization and spending. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses psychiatric manifestations of paraneoplastic disorders; prenatal and neonatal brain structure in children at high risk for schizophrenia; prediction of psychosis by negative and disorganized symptoms in adolescents and young adults; and how histamine-related genes influence the effects of food additives on children’s ADHD symptoms. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses two-phase psychotherapy for PTSD related to childhood abuse, rapid versus gradual discontinuation of antidepressants, augmentation of antidepressants with SAMe, and endogenous opioid function in borderline personality disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the clinical case of a patient with both psychotic and obsessive-compulsive symptoms; the treatment of adolescent depression including 24-week outcomes of the TORDIA study; use of long-term fluoxetine versus lithium for relapse prevention in bipolar II disorder patients; the rationale and features of the Research Domain Criteria, a proposed framework for research on pathophysiology to inform future schemes for classification of mental disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the use of medications for three different types of alcohol dependence; a clinical trial of treatment for comorbid alcohol dependence and depression in which the combination of sertraline and naltrexone was compared with the individual drugs and placebo; a trial of risperidone for maintenance treatment of schizophrenia; recommendations for antipsychotic dosing based on international expert consensus; a 10-year prospective study that tracked remission and recovery from borderline personality disorder in a group of hospitalized patients; a review of the evidence for a dissociative subtype of posttraumatic stress disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a long-term study examining how the depressive state affects the assessment of personality disorder; the pharmacogenetics of antidepressant response; the association between depression and incident diabetes; how brain activity of patients with generalized anxiety disorder reacts to emotional conflict; and the neuropsychiatric aspects of lupus in a patient case that also involved erotomania and the Geschwind syndrome. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a study on structural abnormalities of the thalamus in youth with ADHD, along with an editorial about neuroanatomic findings for the disorder; an 11-year longitudinal study of adult outcomes for girls with ADHD; a study demonstrating that variation in a proto-oncogene is associated with schizophrenia and general cognitive ability; the relationship between neurocognitive functioning and schizophrenia in African Americans. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a case in which a patient attacked a resident to illustrate diagnostic, assessment, and treatment considerations in dealing with violent patients; a clinical trial that compared fluoxetine monotherapy and three combinations of mirtazapine and other antidepressants; recovery from bipolar depression, specifically the impact of substance use disorders; the effect of modafinil on sleep in chronic cocaine users; psychiatric conditions following traumatic injury. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the case of a young woman with catatonia who was treated with ECT; the results of a clinical trial that examined an intervention designed to improve provision of primary medical care for patients in community mental health settings; the results of a clinical trial that compared several doses of long-acting injectable olanzapine for maintenance treatment of patients with schizophrenia; a 30-year prospective study of a New Zealand birth cohort that was able to create a timeline of cognitive deficits during the childhood and early adolescence of subjects who later developed schizophrenia; a long-term study that compared the suicide rates of people with HIV in the years before and after the introduction of highly active antiretroviral therapy; a genetic study that found a relationship between suicidal events and two polymorphisms of a gene affecting the HPA axis in adolescents being treated for depression. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the successful treatment of persistent methamphetamine-induced psychosis with electroconvulsive therapy; using functional MRI to differentiate activation of the amygdala in children with ADHD, bipolar disorder, and severe mood dysregulation; a longitudinal study finding criminality at age 23 to be related to poor fear conditioning at age 3; a long-term study showing that having a mother who experienced depressed mood during pregnancy increases the risk of schizophrenia in offspring with a family history of psychosis; and a clinical trial of integrated treatment for PTSD and substance use that tracked the temporal relationship of improvement in the two conditions. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses cultural aspects of pathological gambling treatment for a woman whose beliefs about gambling are tied to her Haitian background; a longitudinal study of mortality rates for eating disorders that in addition to anorexia nervosa also included bulimia nervosa and diagnoses of “eating disorders not otherwise specified,” which are sometimes considered less severe; predicting depression in the elderly through analyses that identified high-risk individuals for whom prevention was likely to have the greatest health benefit with the lowest implementation burden; a randomized, placebo-controlled clinical treatment trial of adjunctive divalproex for persistent aggressive behavior in children with ADHD following an initial optimized stimulant regimen. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses bipolar II postpartum depression; whether a collaborative care program for veterans with bipolar disorder increased adherence to treatment guidelines over 3 years; how the design of the CATIE study affects the clinical interpretations that can be made; the relationship between neighborhood characteristics and outcomes for dually diagnosed patients; a clinical trial of vigabatrin for cocaine dependence and the ethical issues encountered in the trial. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses take-home messages from the Treatment for Adolescents with Depression Study; change in negative affective bias in depressed patients after one subtherapeutic dose of an antidepressant; association between the familial aggregation of suicide and cluster B personality traits; associations among suicide attempts, gender, and sexual abuse; and a national survey of at-risk and binge drinking among middle-aged and elderly adults. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the treatment of depression in preschool children; the relationship between sudden death and use of stimulant medications in youths; long-term benefits from a short-term quality improvement intervention for depressed youth in primary care; identifying genes that may be relevant to major depression via an overlap between two species in altered gene expression in the anterior cingulate cortex and amygdala; the interaction between family history and prenatal exposure to infection in the causation of schizophrenia; association of substance use disorders with childhood trauma, but not with African genetic heritage, in an African American cohort. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a successful repeat trial of ECT 2 months after an earlier ECT series induced left ventricle cardiomyopathy; manualized short-term psychodynamic psychotherapy versus CBT in the treatment of generalized anxiety disorder; a long-term study differentiating youths with persistent conduct problems from those whose disorder is limited to childhood; an intervention for reducing suicidal ideation and depression in older primary care patients; the relationship between autistic traits in neurotypical adults and functional connectivity in a brain region commonly implicated in social cognition. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses compulsive checking as part of PTSD in veterans of the Iraq and Afghanistan wars; a new foster care network in Bucharest, Romania; the effects of bereavement 21 months after the sudden death of a parent; the 4-year course of bipolar disorder in children and adolescents; an auditory training program designed to improve verbal memory in patients with schizophrenia; and a postmortem analysis differentiating the expression of type 2 and type 3 metabotropic glutamate receptors in the brain to clarify an agonist’s antipsychotic action. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses cognitive complaints and depression following mild traumatic brain injury; cognitive effects of antipsychotic drugs in first-episode patients; the relationship between prenatal infection and executive dysfunction in adults with schizophrenia; activity in the basal ganglia of depressed patients during the anticipatory and consummatory phases of reward processing; whether inhibitory control can be used as a trait marker of ADHD; and a comparison of extended-release paliperidone with quetiapine and placebo for schizophrenia patients requiring hospitalization. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses dynamic psychotherapy for borderline personality disorder; how both major depression and antidepressant treatment affect pregnancy and neonatal outcomes; delusions in the general population; the effect of second-generation antipsychotics on patients with Alzheimer’s disease; and the risk of diabetes mellitus after long-term use of antidepressants. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses treatment of postpartum psychosis; predictors of suicidal events among depressed adolescents receiving antidepressant treatment after an unsuccessful trial of an SSRI; whether clinicians can recognize DSM-IV personality disorders from case descriptions based on the Five-Factor Model of personality; a genome-wide scan of families with Mexican or Central American ancestry that identified two new loci likely to harbor genes that carry a predisposition for schizophrenia and schizoaffective disorder; the isolation of a risk allele associated with schizophrenia; and the relationship between neural habituation in the amygdala and social impairments in autism spectrum disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.