American Journal Of Psychiatry Audio

This month, Deputy Editor Susan K. Schultz, M.D., discusses the diagnosis and treatment of trichotillomania, combining antidepressants with antipsychotics in schizophrenia, outcomes of the FDA reduction in the citalopram maximum dosage, heritable and nonheritable pathways to early callous and unemotional behaviors, and the effect of marriage on the risk for alcohol use disorder. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses accelerometers in diagnosis and treatment of late-life depression, concomitant use of SSRIs and statins, treatment of cognitive impairment in schizophrenia with an alpha-7 nicotinic receptor agonist, the relation of adolescent marijuana use to subclinical psychotic symptoms and to mortality at age 60, and the effect of nicotine exposure during pregnancy to development of schizophrenia in offspring. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses how psychiatrists can extend their role to treatment of general health conditions, how to evaluate randomized clinical trials, interpersonal psychotherapy for mental health problems, fluidity of symptoms in borderline personality disorder, predictors of bipolar illness in offspring of bipolar parents, and the relation of prenatal maternal distress to fetal behavior and to DNA changes in glucocorticoid-related genes in the placenta. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Executive Editor Michael Roy discusses nutrient-based treatments as adjuncts to antidepressants, the prevalence and characteristics of cannabis use disorder as defined in DSM-5, long-term mortality rates in women with severe postpartum psychiatric disorders, a program for children in foster care and their biological parents designed to prevent repetition of childhood maltreatment, whether the relationship between preschool poverty and school-age depression is mediated by functional brain connectivity, and the NIMH Research Domain Criteria project. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Executive Editor Michael Roy discusses a generalist model for treatment of borderline personality disorder, citalopram treatment for agitated patients with Alzheimer’s dementia, buprenorphine for severe suicidal ideation and as an adjunctive treatment in cases of antidepressant nonresponse, effects of prenatal choline supplementation on early-childhood behavior problems, and mechanisms of executive system dysfunction across psychiatric disorders in youths. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses lurasidone for major depression with mixed features, bitemporal ECT compared with high-dose unilateral ECT given twice a week, neurocircuitry of depression with increased versus decreased appetite, attenuated psychosis syndrome, identification of distinct psychosis biotypes, and comprehensive community care for first-episode psychosis. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses depression following stroke; cerebral abnormalities in patients with first-episode schizophrenia; risks of poorly monitored ketamine use for depression; long-term outcomes of light therapy versus CBT for seasonal affective disorder; the reproductive safety of second-generation antipsychotics; and the effects of antipsychotic review and nonpharmacological interventions on antipsychotic use, symptoms, and mortality in nursing home residents. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Executive Editor Michael Roy discusses the risk of postpartum relapse in bipolar disorder and postpartum psychosis, the relation of pregnant women’s defense mechanisms to later behavior in their toddlers, sequential integration of pharmacotherapy and psychotherapy for depression, the dose-response relationship of SSRIs, the effectiveness of clozapine versus standard antipsychotic treatment for schizophrenia, and the relation of prenatal maternal depression, SSRIs, and benzodiazepines to infant neurobehavioral functioning. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses a request for abortion by a woman with major depression and psychosis, an update on prescription opioid abuse, and a consideration of questions about MRI findings of neuropathology underlying psychiatric illness. There also is discussion of predicting response to antipsychotic drugs from baseline striatal functional connectivity, the association between obesity and ADHD, and amygdala hyperactivity during autobiographical recall as a possible trait marker of depression. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses management of alcohol use disorder in patients requiring liver transplant, adding ziprasidone to escitalopram for treatment of depression, attention training for reducing PTSD symptoms, extended-release guanfacine for hyperactivity in autism spectrum disorder, a program for preventing anxiety disorders in offspring of anxious parents, and pregnancy complications following prenatal exposure to SSRIs or maternal psychiatric disorders. Articles may be viewed online at ajp.psychiatryonline.org.

This month, Deputy Editor Susan K. Schultz, M.D., discusses psychiatric symptoms in Wilson's disease, interactions between inflammation and depression, circulating miRNA levels in schizophrenia, the relation of smoking status to later schizophrenia, development of posttraumatic stress disorder in Army servicemembers following traumatic brain injury, and working in the Amish culture. Articles may be viewed online at ajp.psychiatryonline.org.

This audio program explores the role of ketamine and other NMDA antagonists as treatments for depression, and a replication study of a gene-environment interaction affecting depression risk. A study lasting four decades looked at whether ADHD in adults is a childhood-onset disorder, and another longitudinal study followed up adolescents at clinical high risk of psychosis, to see how many of them actually developed psychosis over the follow-up period. There also is discussion of a clinical trial of citicoline for cocaine dependence in bipolar I disorder. Articles may be viewed online at ajp.psychiatryonline.org.

This audio program features a discussion of differential diagnosis of frontotemporal dementia, autoimmune encephalitis in postpartum psychosis, the role of oxytocin in borderline personality disorder, neural correlates of error processing in young people exposed to severe childhood abuse, light therapy versus cognitive-behavioral therapy for seasonal affective disorder, and cognitive enhancement treatment for people with mental illness who do not respond to supported employment. Articles may be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of the role of the psychiatrist in the collaborative care model, pharmacological management of Lewy body dementia, the relationship of depression subtype to antidepressant response, amygdala activity at rest in paranoid individuals with schizophrenia, and the use of clonidine in opioid abstinence to prolong abstinence and decouple stress from craving in daily life. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program explores the diagnostic precursors of bipolar disorder in offspring of bipolar parents, as well as a study examining the intergenerational transmission of anxiety, by looking at the children of twins, and another focusing on separation anxiety disorder in children and adults. Various diagnoses are characterized by impaired response inhibition, and a study is presented of how it relates to neural activation in adolescents with ADHD. Irritability also is a common phenotype, and a longitudinal study tracked the stability of genetic and environmental influences on irritability from childhood to young adulthood. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program features a discussion on a pair of research articles on teenage drinking and on a review article on cognitive-behavioral therapy for anxiety disorders in adolescents. There also is discussion regarding psychiatric care during hepatitis C treatment with direct-acting antivirals, the effects of clozapine on working memory, and the combination of citalopram and methylphenidate for geriatric depression. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program presents a discussion of diagnostic and clinical challenges of narcissistic personality disorder and of two clinical trials of psychotherapy. One examined interpersonal psychotherapy for PTSD, and the other tested the use of brief cognitive-behavioral therapy to reduce suicide attempts in military personnel with a previous history. An additional article compared the effects of different antidepressants on depressed women and looked at outcomes in the women’s children, while another study examined whether the neuroanatomical aspects of autism spectrum disorder lie on a continuum in the general population. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of a study that used an algorithm to search electronic health records for clinical information relevant to the Research Domain Criteria; an article on predicting the transition from mild cognitive impairment to dementia; a trial on reducing reactivity to alcohol cues in patients with alcohol dependence; a study of the relationship between C-reactive protein and symptoms of PTSD; a trial examining the influences of health coaching for overweight persons with serious mental illness; and an intriguing short essay about correspondence between Charles Darwin and the head gardener at an English mental institution. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of adjustment disorder in a health care worker with Ebola, a case of psychotic symptoms that improved with a gluten-free diet, medication prescribing for first-episode schizophrenia, outcomes for young people at ultra-high risk for psychosis who do not transition to psychotic disorders, possible mechanisms in perimenopausal depression, and change during adolescence in reactivity of the amygdala in relation to stressful life events and family history of depression. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a study of postpartum psychosis and mania, a home-visiting intervention for pregnant teenage American Indian mothers, brain patterns underlying learning deficits in autism spectrum disorders, the clusters of genetic variants and clinical features of schizophrenia, the Affordable Care Act and its expansion of insurance for young adults. Articles can be viewed online at ajp.psychiatryonline.org.