Synopsis
Summary of highlights and key articles from each issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association.
Episodes
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January 2020: Maternal Bacterial Infection and Offspring Psychosis Risk
01/01/2020 Duration: 23minExecutive Editor Michael Roy speaks with Younga H. Lee, Ph.D., and Stephen L. Buka, Sc.D., about their research on the association between maternal bacterial infection during pregnancy and risk for psychotic disorders in offspring. The New England Family Study [2:50] Study design [7:21] How information about exposure to bacterial infection was collected, and how offspring who developed mental health problems were evaluated [8:07] Main findings with regard to the connection between exposure to bacterial infection in utero and the development of illness among offspring [11:37] Whether the findings have any bearing on the use of medication to treat infections in pregnancy [12:27] Did any results surprise the researchers? [13:41] What further studies should explore [16:56] Implications of the work [18:12] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Play, Stitcher, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to ot
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December 2019: Dimensions of Psychopathology and Brain Structure
01/12/2019 Duration: 17minExecutive Editor Michael Roy speaks with Antonia Kaczkurkin, Ph.D., and Theodore Satterthwaite, M.D., about their research on how different measures of brain structure (cortical thickness and volume) in youths are associated with various dimensions of psychopathology. What this study aimed to achieve [3:19] Dimensions of psychopathology identified in the study [6:33] Description of a novel method to identify structural brain networks [8:17] Main findings of the research [9:53] Whether information about psychopathology can be gleaned from structural networks in the brain [11:09] What further studies should explore [12:20] Implications of the work [13:11] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Play, Stitcher, Spotify, or wherever you listen to it. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel
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November 2019: CBD for the Reduction of Craving and Anxiety in Heroin Use Disorder
01/11/2019 Duration: 16minExecutive Editor Michael Roy speaks with Yasmin Hurd, Ph.D., about her research on the potential of cannabidiol (CBD) to reduce cue-induced craving and anxiety, two critical features of addiction that often contribute to relapse and continued drug use, in drug-abstinent individuals with heroin use disorder. What has past research with CBD shown in terms of its function as a treatment for mental illness? [2:29] Why the present study examined the potential of CBD to moderate craving and anxiety, and how these reactions were triggered among participants [4:14] How did the study team decide to evaluate CBD at two different doses? [5:54] Main findings of the study [7:42] Discussion of secondary outcomes and adverse events [9:02] Take-home messages for mental health professionals and the general public [11:37] Thoughts on how the medical use of CBD will fit in to the broader trend of the relaxation of marijuana laws throughout the United States [13:28] Be sure to let your colleagues know about the podcast, and p
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September 2019: Sexual Harassment and Gender Discrimination in Health Care
01/09/2019 Duration: 24minGuest host Ann Thomas speaks with Jessica A. Gold, M.D., M.S., and Christina Mangurian, M.D., M.A.S., about their commentary on sexual harassment and gender discrimination in the health care workplace and on how mental health professionals can help remedy these inequities. How pervasive is this problem in health care? [3:13] What are the goals of TIME'S UP Healthcare? [6:57] How are mental health professionals uniquely qualified to develop system-level efforts to promote change? [11:12] What are some key steps mental health care providers can take to raise awareness? [14:12] What progress has been made? [17:23] What does the future hold? [20:10] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Play, Stitcher, Spotify, or wherever you listen to it. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine,
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August 2019: Youth Mental Health Development
01/08/2019 Duration: 23minExecutive Editor Michael Roy speaks with Thorhildur Halldorsdottir, Ph.D., and Elisabeth Binder, M.D., Ph.D., about their research on predicting depression outcomes in youths and how the interaction between FKBP5, a gene involved in regulating the stress system, and early-life exposure to intimate partner violence affects the physiological response to stress early in life, with consequences for emotional and cognitive development. How polygenic risk scores may be used to identify risk for and symptoms of depression in young people [3:32] The interaction between exposure to stress in early life and emotional and cognitive development [8:05] Key points from each study [10:26] Applying gene-by-environment research to real-world work [14:27] What lies ahead in the study of how genes and the environment interact to influence mental health [16:34] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Sp
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July 2019: Treating Negative Symptoms in Schizophrenia
01/07/2019 Duration: 30minExecutive Editor Michael Roy speaks with Roscoe O. Brady, Jr., M.D., Ph.D., and Mark A. Halko, Ph.D., about their research on identifying and treating a network of connectivity in the brain corresponding to negative symptom severity in schizophrenia. The difference between positive and negative symptoms in psychosis, and why the symptoms are important [2:39] Identifying the treating the underlying circuitry of negative symptoms in the brain [6:25] Discussion of the results of the study [10:20] Symptom severity and the link between the prefrontal cortex and cerebellum [12:27] Aspects of the study that are relevant for researchers, clinicians, and other mental health professionals [20:40] What's next in this line of research and clinical care [25:40] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Listen to other podcasts produced by the American Psychiatric Association. Browse articl
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June 2019: Treating Adults With Anorexia Nervosa
01/06/2019 Duration: 20minExecutive Editor Michael Roy speaks with Evelyn Attia, M.D., about her research evaluating the benefits of olanzapine compared with placebo for adult outpatients with anorexia nervosa. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the issue. Follow the Journal on Twitter. E-mail us at ajp@psych.org
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May 2019: The Clinical Utility of Irritability in Major Depressive Disorder
01/05/2019 Duration: 21minExecutive Editor Michael Roy speaks with Madhukar H. Trivedi, M.D., about his research evaluating the clinical utility of adding irritability to the current paradigm of measuring depressive symptom severity during the course of antidepressant treatment. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the issue. Follow the Journal on Twitter. E-mail us at ajp@psych.org
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April 2019: Patient Treatment Preference for PTSD
01/04/2019 Duration: 13minExecutive Editor Michael Roy speaks with Lori A. Zoellner, Ph.D., about her research on how patient treatment preference affects outcomes in the treatment of posttraumatic stress disorder (PTSD). In a doubly randomized preference trial, 200 patients with PTSD viewed standardized treatment rationales prior to randomization. Patients were first randomized to choice of treatment or no choice. Those assigned to no choice were then randomized to prolonged exposure or sertraline. Acute treatment was 10 weeks, with 24-month follow-up. Interviewer-rated PTSD symptom severity was the main outcome measure, and depression, anxiety, and functioning were assessed as additional outcomes. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the is
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March 2019: Self-Harm and Violent Crime
01/03/2019 Duration: 12minExecutive Editor Michael Roy speaks with Leah S. Richmond-Rakerd, Ph.D., about her research on the antecedents, clinical features, and life characteristics of adolescents who engage in both self-harming and violent criminal behaviors. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the issue. Follow the Journal on Twitter. E-mail us at ajp@psych.org
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February 2019 Highlights
01/02/2019 Duration: 24minExecutive Editor Michael Roy speaks with Patricia J. Conrod, Ph.D., about her research on the relationship between substance use and adolescent cognitive development. Deputy Editor Kathleen T. Brady, M.D., Ph.D., discusses her editorial on improving our understanding of substance use disorders. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the issue. Follow the Journal on Twitter.
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January 2019 Highlights
01/01/2019 Duration: 11minThis month, Ned H. Kalin, M.D., begins his term as Editor-in-Chief of the Journal. Speaking with Executive Editor Michael Roy, Dr. Kalin outlines his vision for his tenure and discusses the kinds of research that will appear in the Journal.
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December 2018 Highlights
01/12/2018 Duration: 31minOutgoing Editor-in-Chief Robert Freedman, M.D., reflects on his tenure as Editor of the Journal. Executive Editor Michael Roy reviews research on the management of vascular depression, the use of prazosin for alcohol use disorder, and how maternal severe mental illness and exposure to obstetric complications are associated with intellectual disability and psychotic disorders in children.
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November 2018 Highlights
01/11/2018 Duration: 14minThis month, host Ann Thomas talks with Alan S. Brown, M.D., M.P.H., about his research on the association of maternal insecticide levels with autism, and on maternal immune activation and neuropsychiatric illness. Executive Editor Michael Roy reviews research on how smoking affects cognitive functioning, a randomized controlled trial of parent-child psychotherapy, and challenges in managing mental health problems in transgender individuals.
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October 2018 Highlights
01/10/2018 Duration: 25minThis month, Executive Editor Michael Roy talks with Jill E. Bormann, Ph.D., R.N., about her research on "mantram" repetition therapy to treat PTSD in veterans. Other highlights: how insight affects outcome in psychotherapy, how medications for addictive behaviors affect crime and suicide, how electronic health records can be used to predict suicide attempts, and the mental health impact of violence toward targeted populations.
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September 2018 Highlights
01/09/2018 Duration: 22minThis month, Executive Editor Michael Roy talks with Betsy D. Kennard, Psy.D., about her research on an inpatient intervention and smartphone app to reduce adolescent suicide attempts following hospital discharge. Other highlights: care of patients with nonepileptic seizures; how sudden parental death affects depression in children; computerized CBT for addiction treatment; and the relationship between abortion and suicidal ideation.
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August 2018 Highlights
01/08/2018 Duration: 21minThis month, Executive Editor Michael Roy talks with Wilson M. Compton, M.D., M.P.E., about his research on patterns of misuse of prescription stimulant medication in the United States. Other highlights: burnout among physicians, whether depression causes premature aging, discontinuation of antipsychotic treatment in schizophrenia, and risk of postpartum psychiatric episodes.
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July 2018 Highlights
01/07/2018 Duration: 27minThis month, Executive Editor Michael Roy talks with M. Camille Hoffman, M.D., about her research on the use of nutritional supplements in pregnancy. Michael Roy also speaks with Daniel S. Pine, M.D., Deputy Editor of the Journal, about a clinical trial involving ketamine and whether a framework can be established for the safe use of ketamine. Other highlights: how physical activity can affect depression, and treatment of alcohol-dependent adults who are involved with the criminal justice system.
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June 2018 Highlights
01/06/2018 Duration: 26minThis month, Avshalom Caspi, Ph.D., talks about his research on the relationship between early-life stress and later changes in DNA methylation. Executive Editor Michael Roy reviews a unique form of episodic psychosis, health care use before an opioid-related death, new genetic markers for depression, and the effect of antipsychotic medication on the risk for diabetes in pregnancy.